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Volumn 120, Issue 14, 2012, Pages 2899-2908

Heparan sulfate, an endogenous TLR4 agonist, promotes acute GVHD after allogeneic stem cell transplantation

Author keywords

[No Author keywords available]

Indexed keywords

B7 ANTIGEN; CD40 ANTIGEN; FIBRINOGEN; FIBRONECTIN; GAMMA INTERFERON; HEAT SHOCK PROTEIN 70; HEPARAN SULFATE; HIGH MOBILITY GROUP B1 PROTEIN; INTERLEUKIN 12; INTERLEUKIN 6; INTERLEUKIN 8; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TRYPSIN INHIBITOR;

EID: 84867316465     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2011-07-368720     Document Type: Article
Times cited : (98)

References (48)
  • 1
    • 33646119401 scopus 로고    scopus 로고
    • Hematopoietic stem-cell transplantation
    • Copelan EA. Hematopoietic stem-cell transplantation. N Engl J Med. 2006;354(17):1813-1826.
    • (2006) N Engl J Med , vol.354 , Issue.17 , pp. 1813-1826
    • Copelan, E.A.1
  • 3
    • 34247867901 scopus 로고    scopus 로고
    • Immunobiology of allogeneic hematopoietic stem cell transplantation
    • DOI 10.1146/annurev.immunol.25.022106.141606
    • Welniak LA, Blazar BR, Murphy WJ. Immunobiology of allogeneic hematopoietic stem cell transplantation. Annu Rev Immunol. 2007;25:139-170. (Pubitemid 46697905)
    • (2007) Annual Review of Immunology , vol.25 , pp. 139-170
    • Welniak, L.A.1    Blazar, B.R.2    Murphy, W.J.3
  • 4
    • 79960270124 scopus 로고    scopus 로고
    • Low risk of chronic graft-versus-host disease and relapse associated with T cell-depleted peripheral blood stem cell transplantation for acute myelogenous leukemia in first remission: Results of the Blood and Marrow Transplant Clinical Trials Network Protocol 0303
    • Devine SM, Carter S, Soiffer RJ, et al. Low risk of chronic graft-versus-host disease and relapse associated with T cell-depleted peripheral blood stem cell transplantation for acute myelogenous leukemia in first remission: results of the Blood and Marrow Transplant Clinical Trials Network Protocol 0303. Biol Blood Marrow Transplant. 2011;17(9):1343-1351.
    • (2011) Biol Blood Marrow Transplant , vol.17 , Issue.9 , pp. 1343-1351
    • Devine, S.M.1    Carter, S.2    Soiffer, R.J.3
  • 5
    • 0028208561 scopus 로고
    • Control of graft-versus-host disease and graft rejection by T cell depletion of donor and recipient with Campath-1 antibodies. Results of matched sibling transplants for malignant diseases
    • Hale G, Waldmann H. Control of graft-versus-host disease and graft rejection by T cell depletion of donor and recipient with Campath-1 antibodies. Results of matched sibling transplants for malignant diseases. Bone Marrow Transplant. 1994;13(5):597-611. (Pubitemid 24141188)
    • (1994) Bone Marrow Transplantation , vol.13 , Issue.5 , pp. 597-611
    • Hale, G.1    Waldmann, H.2
  • 6
    • 36048953433 scopus 로고    scopus 로고
    • Higher Risk of Cytomegalovirus and Aspergillus Infections in Recipients of T Cell-Depleted Unrelated Bone Marrow: Analysis of Infectious Complications in Patients Treated with T Cell Depletion Versus Immunosuppressive Therapy to Prevent Graft-versus-Host Disease
    • DOI 10.1016/j.bbmt.2007.08.049, PII S1083879107004405
    • van Burik JA, Carter SL, Freifeld AG, et al. Higher risk of cytomegalovirus and aspergillus infections in recipients of T cell-depleted unrelated bone marrow: analysis of infectious complications in patients treated with T cell depletion versus immunosuppressive therapy to prevent graft-versus-host disease. Biol Blood Marrow Transplant. 2007;13(12):1487-1498. (Pubitemid 350091387)
    • (2007) Biology of Blood and Marrow Transplantation , vol.13 , Issue.12 , pp. 1487-1498
    • Van Burik, J.-A.H.1    Carter, S.L.2    Freifeld, A.G.3    High, K.P.4    Godder, K.T.5    Papanicolaou, G.A.6    Mendizabal, A.M.7    Wagner, J.E.8    Yanovich, S.9    Kernan, N.A.10
  • 7
    • 79952696140 scopus 로고    scopus 로고
    • Prevention of GVHD without losing GVL effect: Windows of opportunity
    • Zhang P, Chen BJ, Chao NJ. Prevention of GVHD without losing GVL effect: windows of opportunity. Immunol Res. 2011;49(1-3):49-55.
    • (2011) Immunol Res , vol.49 , Issue.1-3 , pp. 49-55
    • Zhang, P.1    Chen, B.J.2    Chao, N.J.3
  • 8
    • 77953500856 scopus 로고    scopus 로고
    • Allogeneic immunotherapy to optimize the graft-versus-tumor effect: Concepts and controversies
    • Goldstein SC, Porter DL. Allogeneic immunotherapy to optimize the graft-versus-tumor effect: concepts and controversies. Expert Rev Hematol. 2010;3(3):301-314.
    • (2010) Expert Rev Hematol , vol.3 , Issue.3 , pp. 301-314
    • Goldstein, S.C.1    Porter, D.L.2
  • 9
    • 32944464648 scopus 로고    scopus 로고
    • Pathogen recognition and innate immunity
    • DOI 10.1016/j.cell.2006.02.015, PII S0092867406001905
    • Akira S, Uematsu S, Takeuchi O. Pathogen recognition and innate immunity. Cell. 2006;124(4):783-801. (Pubitemid 43261452)
    • (2006) Cell , vol.124 , Issue.4 , pp. 783-801
    • Akira, S.1    Uematsu, S.2    Takeuchi, O.3
  • 10
    • 0036839577 scopus 로고    scopus 로고
    • Endogenous ligands of Toll-like receptors: Implications for regulating inflammatory and immune responses
    • DOI 10.1016/S1471-4906(02)02317-7, PII S1471490602023177
    • Beg AA. Endogenous ligands of Toll-like receptors: implications for regulating inflammatory and immune responses. Trends Immunol. 2002;23(11):509-512. (Pubitemid 35223541)
    • (2002) Trends in Immunology , vol.23 , Issue.11 , pp. 509-512
    • Beg, A.A.1
  • 11
    • 4344627821 scopus 로고    scopus 로고
    • Endogenous ligands of Toll-like receptors
    • DOI 10.1189/jlb.0304127
    • Tsan MF, Gao B. Endogenous ligands of Toll-like receptors. J Leukoc Biol. 2004;76(3):514-519. (Pubitemid 39129081)
    • (2004) Journal of Leukocyte Biology , vol.76 , Issue.3 , pp. 514-519
    • Tsan, M.-F.1    Gao, B.2
  • 12
    • 77951260924 scopus 로고    scopus 로고
    • The role of patternrecognition receptors in innate immunity: Update on Toll-like receptors
    • Kawai T, Akira S. The role of patternrecognition receptors in innate immunity: update on Toll-like receptors. Nat Immunol. 2010;11(5):373-384.
    • (2010) Nat Immunol , vol.11 , Issue.5 , pp. 373-384
    • Kawai, T.1    Akira, S.2
  • 13
    • 77954809558 scopus 로고    scopus 로고
    • Targeting the TLR9-MyD88 pathway in the regulation of adaptive immune responses
    • Huang X, Yang Y. Targeting the TLR9-MyD88 pathway in the regulation of adaptive immune responses. Expert Opin Ther Targets. 2010;14(8):787-796.
    • (2010) Expert Opin Ther Targets , vol.14 , Issue.8 , pp. 787-796
    • Huang, X.1    Yang, Y.2
  • 15
    • 0037974914 scopus 로고    scopus 로고
    • Critical role of the Toll-like receptor signal adaptor protein MyD88 in acute allograft rejection
    • DOI 10.1172/JCI200317573
    • Goldstein DR, Tesar BM, Akira S, Lakkis FG. Critical role of the Toll-like receptor signal adaptor protein MyD88 in acute allograft rejection. J Clin Invest. 2003;111(10):1571-1578. (Pubitemid 38063290)
    • (2003) Journal of Clinical Investigation , vol.111 , Issue.10 , pp. 1571-1578
    • Goldstein, D.R.1    Tesar, B.M.2    Akira, S.3    Lakkis, F.G.4
  • 17
    • 54049153247 scopus 로고    scopus 로고
    • TLR agonists regulate alloresponses and uncover a critical role for donor APCs in allogeneic bone marrow rejection
    • Taylor PA, Ehrhardt MJ, Lees CJ, et al. TLR agonists regulate alloresponses and uncover a critical role for donor APCs in allogeneic bone marrow rejection. Blood. 2008;112(8):3508-3516.
    • (2008) Blood , vol.112 , Issue.8 , pp. 3508-3516
    • Taylor, P.A.1    Ehrhardt, M.J.2    Lees, C.J.3
  • 18
    • 66449113934 scopus 로고    scopus 로고
    • Hyaluronan mediates ozone-induced airway hyperresponsiveness in mice
    • Garantziotis S, Li Z, Potts EN, et al. Hyaluronan mediates ozone-induced airway hyperresponsiveness in mice. J Biol Chem. 2009;284(17):11309-11317.
    • (2009) J Biol Chem , vol.284 , Issue.17 , pp. 11309-11317
    • Garantziotis, S.1    Li, Z.2    Potts, E.N.3
  • 19
    • 2442655250 scopus 로고    scopus 로고
    • Persistent Toll-like receptor signals are required for reversal of regulatory T cell-mediated CD8 tolerance
    • DOI 10.1038/ni1059
    • Yang Y, Huang CT, Huang X, Pardoll DM. Persistent Toll-like receptor signals are required for reversal of regulatory T cell-mediated CD8 tolerance. Nat Immunol. 2004;5(5):508-515. (Pubitemid 38660463)
    • (2004) Nature Immunology , vol.5 , Issue.5 , pp. 508-515
    • Yang, Y.1    Huang, C.-T.2    Huang, X.3    Pardoll, D.M.4
  • 20
    • 0029909099 scopus 로고    scopus 로고
    • An experimental model of idiopathic pneumonia syndrome after bone marrow transplantation: 1. The roles of minor H antigens and endotoxin
    • Cooke KR, Kobzik L, Martin TR, et al. An experimental model of idiopathic pneumonia syndrome after bone marrow transplantation: I. The roles of minor H antigens and endotoxin. Blood. 1996;88(8):3230-3239. (Pubitemid 26357409)
    • (1996) Blood , vol.88 , Issue.8 , pp. 3230-3239
    • Cooke, K.R.1    Kobzik, L.2    Martin, T.R.3    Brewer, J.4    Delmonte Jr., J.5    Crawford, J.M.6    Ferrara, J.L.M.7
  • 22
    • 38549140009 scopus 로고    scopus 로고
    • + direct pathway: Level of priming determines acute versus chronic rejection
    • DOI 10.1097/TP.0b013e31815e883e, PII 0000789020080127000013
    • Brennan TV, Hoang V, Garrod KR, et al. A new T-cell receptor transgenic model of the CD4+ direct pathway: level of priming determines acute versus chronic rejection. Transplantation. 2008;85(2):247-255. (Pubitemid 351156855)
    • (2008) Transplantation , vol.85 , Issue.2 , pp. 247-255
    • Brennan, T.V.1    Hoang, V.2    Garrod, K.R.3    Liu, F.-C.4    Hayden, T.5    Kim, J.6    Kang, S.-M.7
  • 23
    • 0037094084 scopus 로고    scopus 로고
    • Receptor-mediated monitoring of tissue well-being via detection of soluble heparan sulfate by toll-like receptor 4
    • Johnson GB, Brunn GJ, Kodaira Y, Platt JL. Receptor-mediated monitoring of tissue well-being via detection of soluble heparan sulfate by Toll-like receptor 4. J Immunol. 2002;168(10):5233-5239. (Pubitemid 34495991)
    • (2002) Journal of Immunology , vol.168 , Issue.10 , pp. 5233-5239
    • Johnson, G.B.1    Brunn, G.J.2    Kodaira, Y.3    Platt, J.L.4
  • 24
    • 0347994943 scopus 로고    scopus 로고
    • Cutting Edge: An Endogenous Pathway to Systemic Inflammatory Response Syndrome (SIRS)-Like Reactions through Toll-Like Receptor 4
    • Johnson GB, Brunn GJ, Platt JL. Cutting edge: an endogenous pathway to systemic inflammatory response syndrome (SIRS)-like reactions through Toll-like receptor 4. J Immunol. 2004;172(1):20-24. (Pubitemid 38020450)
    • (2004) Journal of Immunology , vol.172 , Issue.1 , pp. 20-24
    • Johnson, G.B.1    Brunn, G.J.2    Platt, J.L.3
  • 26
    • 67649390890 scopus 로고    scopus 로고
    • Clinical practice. Alpha1-antitrypsin deficiency
    • Silverman EK, Sandhaus RA. Clinical practice. Alpha1-antitrypsin deficiency. N Engl J Med. 2009;360(26):2749-2757.
    • (2009) N Engl J Med , vol.360 , Issue.26 , pp. 2749-2757
    • Silverman, E.K.1    Sandhaus, R.A.2
  • 27
    • 55849101706 scopus 로고    scopus 로고
    • Alpha1-Antitrypsin monotherapy induces immune tolerance during islet allograft transplantation in mice
    • Lewis EC, Mizrahi M, Toledano M, et al. alpha1-Antitrypsin monotherapy induces immune tolerance during islet allograft transplantation in mice. Proc Natl Acad Sci U S A. 2008;105(42):16236-16241.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , Issue.42 , pp. 16236-16241
    • Lewis, E.C.1    Mizrahi, M.2    Toledano, M.3
  • 28
    • 79951676056 scopus 로고    scopus 로고
    • PG545, a dual heparanase and angiogenesis inhibitor, induces potent anti-tumour and anti-metastatic efficacy in preclinical models
    • Dredge K, Hammond E, Handley P, et al. PG545, a dual heparanase and angiogenesis inhibitor, induces potent anti-tumour and anti-metastatic efficacy in preclinical models. Br J Cancer. 2011;104(4):635-642.
    • (2011) Br J Cancer , vol.104 , Issue.4 , pp. 635-642
    • Dredge, K.1    Hammond, E.2    Handley, P.3
  • 29
    • 74549167783 scopus 로고    scopus 로고
    • Regulation of adaptive immunity by the innate immune system
    • Iwasaki A, Medzhitov R. Regulation of adaptive immunity by the innate immune system. Science. 2010;327(5963):291-295.
    • (2010) Science , vol.327 , Issue.5963 , pp. 291-295
    • Iwasaki, A.1    Medzhitov, R.2
  • 31
    • 0037080024 scopus 로고    scopus 로고
    • Tissue expression of human Toll-like receptors and differential regulation of Toll-like receptor mRNAs in leukocytes in response to microbes, their products, and cytokines
    • Zarember KA, Godowski PJ. Tissue expression of human Toll-like receptors and differential regulation of Toll-like receptor mRNAs in leukocytes in response to microbes, their products, and cytokines. J Immunol. 2002;168(2):554-561. (Pubitemid 34049553)
    • (2002) Journal of Immunology , vol.168 , Issue.2 , pp. 554-561
    • Zarember, K.A.1    Godowski, P.J.2
  • 32
    • 63849167957 scopus 로고    scopus 로고
    • A critical role for direct TLR2-MyD88 signaling in CD8 T-cell clonal expansion and memory formation following vaccinia viral infection
    • Quigley M, Martinez J, Huang X, Yang Y. A critical role for direct TLR2-MyD88 signaling in CD8 T-cell clonal expansion and memory formation following vaccinia viral infection. Blood. 2009;113(10):2256-2264.
    • (2009) Blood , vol.113 , Issue.10 , pp. 2256-2264
    • Quigley, M.1    Martinez, J.2    Huang, X.3    Yang, Y.4
  • 33
    • 33846122035 scopus 로고    scopus 로고
    • + T Cells and Enables CpG Oligodeoxynucleotide-Mediated Costimulation
    • DOI 10.1016/j.immuni.2006.08.023, PII S1074761306004420
    • Gelman AE, LaRosa DF, Zhang J, et al. The adaptor molecule MyD88 activates PI-3 kinase signaling in CD4+ T cells and enables CpG oligodeoxynucleotide-mediated costimulation. Immunity. 2006;25(5):783-793. (Pubitemid 46107281)
    • (2006) Immunity , vol.25 , Issue.5 , pp. 783-793
    • Gelman, A.E.1    LaRosa, D.F.2    Zhang, J.3    Walsh, P.T.4    Choi, Y.5    Sunyer, J.6    Turka, L.A.7
  • 34
    • 79251544215 scopus 로고    scopus 로고
    • Graft-versus-host disease is independent of innate signaling pathways triggered by pathogens in host hematopoietic cells
    • Li H, Matte-Martone C, Tan HS, et al. Graft-versus-host disease is independent of innate signaling pathways triggered by pathogens in host hematopoietic cells. J Immunol. 2011;186(1):230-241.
    • (2011) J Immunol , vol.186 , Issue.1 , pp. 230-241
    • Li, H.1    Matte-Martone, C.2    Tan, H.S.3
  • 36
  • 39
    • 68849119321 scopus 로고    scopus 로고
    • Mice that exclusively express TLR4 on endothelial cells can efficiently clear a lethal systemic Gram-negative bacterial infection
    • Andonegui G, Zhou H, Bullard D, et al. Mice that exclusively express TLR4 on endothelial cells can efficiently clear a lethal systemic Gram-negative bacterial infection. J Clin Invest. 2009;119(7):1921-1930.
    • (2009) J Clin Invest , vol.119 , Issue.7 , pp. 1921-1930
    • Andonegui, G.1    Zhou, H.2    Bullard, D.3
  • 40
    • 80052493237 scopus 로고    scopus 로고
    • Danger signals activating innate immunity in graft-versus-host disease
    • Zeiser R, Penack O, Holler E, Idzko M. Danger signals activating innate immunity in graft-versus-host disease. J Mol Med. 2011;89(9):833-845.
    • (2011) J Mol Med , vol.89 , Issue.9 , pp. 833-845
    • Zeiser, R.1    Penack, O.2    Holler, E.3    Idzko, M.4
  • 41
    • 0042767994 scopus 로고    scopus 로고
    • Increased levels of Syndecan-1 in serum during acute graft-versus-host disease
    • DOI 10.1097/01.TP.0000074316.76104.A5
    • Seidel C, Ringden O, Remberger M. Increased levels of syndecan-1 in serum during acute graft-versus-host disease. Transplantation. 2003;76(2):423-426. (Pubitemid 36928010)
    • (2003) Transplantation , vol.76 , Issue.2 , pp. 423-426
    • Seidel, C.1    Ringden, O.2    Remberger, M.3
  • 42
    • 0021249299 scopus 로고
    • Activated T lymphocytes produce a matrix-degrading heparan sulphate endoglycosidase
    • Naparstek Y, Cohen IR, Fuks Z, Vlodavsky I. Activated T lymphocytes produce a matrix-degrading heparan sulphate endoglycosidase. Nature. 1984;310(5974):241-244. (Pubitemid 14090715)
    • (1984) Nature , vol.310 , Issue.5974 , pp. 241-244
    • Naparstek, Y.1    Cohen, I.R.2    Fuks, Z.3    Vlodavsky, I.4
  • 43
    • 77956336184 scopus 로고    scopus 로고
    • Heparanase promotes engraftment and prevents graft versus host disease in stem cell transplantation
    • Bitan M, Weiss L, Zeira M, et al. Heparanase promotes engraftment and prevents graft versus host disease in stem cell transplantation. PLoS One. 2010;5(4):e10135.
    • (2010) PLoS One , vol.5 , Issue.4
    • Bitan, M.1    Weiss, L.2    Zeira, M.3
  • 44
    • 77952546530 scopus 로고    scopus 로고
    • Heparanase upregulates Th2 cytokines, ameliorating experimental autoimmune encephalitis
    • Bitan M, Weiss L, Reibstein I, et al. Heparanase upregulates Th2 cytokines, ameliorating experimental autoimmune encephalitis. Mol Immunol. 2010;47(10):1890-1898.
    • (2010) Mol Immunol , vol.47 , Issue.10 , pp. 1890-1898
    • Bitan, M.1    Weiss, L.2    Reibstein, I.3
  • 45
    • 49449109114 scopus 로고    scopus 로고
    • Heparanase prevents the development of type 1 diabetes in nonobese diabetic mice by regulating T-cell activation and cytokines production
    • Bitan M, Weiss L, Zeira M, et al. Heparanase prevents the development of type 1 diabetes in nonobese diabetic mice by regulating T-cell activation and cytokines production. Diabetes Metab Res Rev. 2008;24(5):413-421.
    • (2008) Diabetes Metab Res Rev , vol.24 , Issue.5 , pp. 413-421
    • Bitan, M.1    Weiss, L.2    Zeira, M.3
  • 46
    • 55849136929 scopus 로고    scopus 로고
    • Curative and beta cell regenerative effects of alpha1-antitrypsin treatment in autoimmune diabetic NOD mice
    • Koulmanda M, Bhasin M, Hoffman L, et al. Curative and beta cell regenerative effects of alpha1-antitrypsin treatment in autoimmune diabetic NOD mice. Proc Natl Acad Sci U S A. 2008;105(42):16242-16247.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , Issue.42 , pp. 16242-16247
    • Koulmanda, M.1    Bhasin, M.2    Hoffman, L.3
  • 47
    • 80855128776 scopus 로고    scopus 로고
    • Inhibition of IL-32 activation by alpha-1 antitrypsin suppresses alloreactivity and increases survival in an allogeneic murine marrow transplantation model
    • Marcondes AM, Li X, Tabellini L, et al. Inhibition of IL-32 activation by alpha-1 antitrypsin suppresses alloreactivity and increases survival in an allogeneic murine marrow transplantation model. Blood. 2011;118(18):5031-5039.
    • (2011) Blood , vol.118 , Issue.18 , pp. 5031-5039
    • Marcondes, A.M.1    Li, X.2    Tabellini, L.3
  • 48
    • 84862908801 scopus 로고    scopus 로고
    • Alpha-1-antitrypsin monotherapy reduces graft-versus-host disease after experimental allogeneic bone marrow transplantation
    • Tawara I, Sun Y, Lewis EC, et al. Alpha-1-antitrypsin monotherapy reduces graft-versus-host disease after experimental allogeneic bone marrow transplantation. Proc Natl Acad Sci U S A. 2012;109(2):564-569.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , Issue.2 , pp. 564-569
    • Tawara, I.1    Sun, Y.2    Lewis, E.C.3


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