Gremlin inhibits UV-induced skin cell damages via activating VEGFR2-Nrf2 signaling

Oncotarget

Volumn 7, Issue 51, 2016, Pages 84748-84757

  Ji, Chao ^a   Huang, Jin wen ^a   Xu, Qiu yun ^a   Zhang, Jing ^a   Lin, Meng ting ^a   Tu, Ying ^b   He, Li ^b   Bi, Zhi gang ^c   Cheng, Bo ^a  

^a FUJIAN MEDICAL UNIVERSITY   (China)

^b KUNMING MEDICAL UNIVERSITY   (China)

^c NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Gremlin; Nrf2; Skin cell damage; Ultra violet (UV); VEGFR2

Indexed keywords

GREMLIN; REACTIVE OXYGEN METABOLITE; SHORT HAIRPIN RNA; SINGLE STRANDED DNA; SKIN PROTECTIVE AGENT; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG; VASCULOTROPIN RECEPTOR 2; GREM1 PROTEIN, HUMAN; KDR PROTEIN, HUMAN; NFE2L2 PROTEIN, HUMAN; SIGNAL PEPTIDE; SMALL INTERFERING RNA;

ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL DAMAGE; CELL DEATH; CELL PROTECTION; CONTROLLED STUDY; DNA STRAND BREAKAGE; DRUG MECHANISM; GENE MUTATION; GENE SILENCING; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; KERATINOCYTE; RADIATION INJURY; RADIATION PROTECTION; RECEPTOR BLOCKING; SKIN CELL; SKIN FIBROBLAST; SKIN PROTECTION; ULTRAVIOLET RADIATION; AGONISTS; CELL CULTURE; DNA DAMAGE; FIBROBLAST; GENETICS; METABOLISM; PATHOLOGY; RADIATION RESPONSE; SIGNAL TRANSDUCTION; SINGLE STRANDED DNA BREAK; SKIN;

CELLS, CULTURED; CYTOPROTECTION; DNA BREAKS, SINGLE-STRANDED; DNA DAMAGE; FIBROBLASTS; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; KERATINOCYTES; NF-E2-RELATED FACTOR 2; REACTIVE OXYGEN SPECIES; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SKIN; ULTRAVIOLET RAYS; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2;

EID: 85007480342     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.12454     Document Type: Article

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