Gremlin utilizes canonical and non-canonical TGFβ signaling to induce lysyl oxidase (LOX) genes in human trabecular meshwork cells

Experimental Eye Research

Volumn 113, Issue , 2013, Pages 117-127

  Sethi, Anirudh ^a,b   Wordinger, Robert J ^a   Clark, Abbot F ^a  

^a UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Extracellular matrix; Gremlin; Lysyl oxidase; Lysyl oxidase like; Primary open angle glaucoma; Trabecular meshwork; Transforming growth factor beta

Indexed keywords

BONE MORPHOGENETIC PROTEIN; GREMLIN; PROTEIN; PROTEIN LYSINE 6 OXIDASE; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ARTICLE; CELL CULTURE; CELL LYSATE; CONTROLLED STUDY; EXTRACELLULAR MATRIX; GENE EXPRESSION; GLAUCOMA; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; PATHOGENESIS; PHOSPHORYLATION; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRABECULAR MESHWORK; WESTERN BLOTTING;

EXTRACELLULAR MATRIX; GREMLIN; LYSYL OXIDASE; LYSYL OXIDASE LIKE; PRIMARY OPEN ANGLE GLAUCOMA; TRABECULAR MESHWORK; TRANSFORMING GROWTH FACTOR BETA;

BLOTTING, WESTERN; BONE MORPHOGENETIC PROTEINS; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; EXTRACELLULAR MATRIX; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; PHOSPHORYLATION; PROTEIN-LYSINE 6-OXIDASE; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; TIME FACTORS; TRABECULAR MESHWORK; TRANSFORMING GROWTH FACTOR BETA2;

EID: 84879590793     PISSN: 00144835     EISSN: 10960007     Source Type: Journal    
DOI: 10.1016/j.exer.2013.05.011     Document Type: Article

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