-
2
-
-
79851472312
-
The in vivo kinetics of RNA polymerase II elongation during co-transcriptional splicing
-
Brody Y, Neufeld N, Bieberstein N, Causse SZ, Bohnlein EM, Neugebauer KM, Darzacq X, Shav-Tal Y. 2011. The in vivo kinetics of RNA polymerase II elongation during co-transcriptional splicing. PLoS Biol 9: e1000573.
-
(2011)
Plos Biol
, vol.9
-
-
Brody, Y.1
Neufeld, N.2
Bieberstein, N.3
Causse, S.Z.4
Bohnlein, E.M.5
Neugebauer, K.M.6
Darzacq, X.7
Shav-Tal, Y.8
-
3
-
-
24044489892
-
The interaction of LEDGF/p75 with integrase is lentivirus-specific and promotes DNA binding
-
Busschots K, Vercammen J, Emiliani S, Benarous R, Engelborghs Y, Christ F, Debyser Z. 2005. The interaction of LEDGF/p75 with integrase is lentivirus-specific and promotes DNA binding. J Biol Chem 280: 17841-17847.
-
(2005)
J Biol Chem
, vol.280
, pp. 17841-17847
-
-
Busschots, K.1
Vercammen, J.2
Emiliani, S.3
Benarous, R.4
Engelborghs, Y.5
Christ, F.6
Debyser, Z.7
-
4
-
-
0346036088
-
HIV-1 integrase forms stable tetramers and associates with LEDGF/p75 protein in human cells
-
Cherepanov P, Maertens G, Proost P, Devreese B, Van Beeumen J, Engelborghs Y, De Clercq E, Debyser Z. 2003. HIV-1 integrase forms stable tetramers and associates with LEDGF/p75 protein in human cells. J Biol Chem 278: 372-381.
-
(2003)
J Biol Chem
, vol.278
, pp. 372-381
-
-
Cherepanov, P.1
Maertens, G.2
Proost, P.3
Devreese, B.4
Van Beeumen, J.5
Engelborghs, Y.6
De Clercq, E.7
Debyser, Z.8
-
5
-
-
10344221084
-
Identification of an evolutionarily conserved domain in human lens epithelium-derived growth factor/transcriptional co-activator p75 (LEDGF/p75) that binds HIV-1 integrase
-
Cherepanov P, Devroe E, Silver PA, Engelman A. 2004. Identification of an evolutionarily conserved domain in human lens epithelium-derived growth factor/transcriptional co-activator p75 (LEDGF/p75) that binds HIV-1 integrase. J Biol Chem 279: 48883-48892.
-
(2004)
J Biol Chem
, vol.279
, pp. 48883-48892
-
-
Cherepanov, P.1
Devroe, E.2
Silver, P.A.3
Engelman, A.4
-
6
-
-
28444445583
-
Structural basis for the recognition between HIV-1 integrase and transcriptional coactivator p75
-
Cherepanov P, Ambrosio AL, Rahman S, Ellenberger T, Engelman A. 2005. Structural basis for the recognition between HIV-1 integrase and transcriptional coactivator p75. Proc Natl Acad Sci 102: 17308-17313.
-
(2005)
Proc Natl Acad Sci
, vol.102
, pp. 17308-17313
-
-
Cherepanov, P.1
Ambrosio, A.L.2
Rahman, S.3
Ellenberger, T.4
Engelman, A.5
-
7
-
-
28644443483
-
A role for LEDGF/p75 in targeting HIV DNA integration
-
Ciuffi A, Llano M, Poeschla E, Hoffmann C, Leipzig J, Shinn P, Ecker JR, Bushman F. 2005. A role for LEDGF/p75 in targeting HIV DNA integration. Nat Med 11: 1287-1289.
-
(2005)
Nat Med
, vol.11
, pp. 1287-1289
-
-
Ciuffi, A.1
Llano, M.2
Poeschla, E.3
Hoffmann, C.4
Leipzig, J.5
Shinn, P.6
Ecker, J.R.7
Bushman, F.8
-
8
-
-
84922249841
-
HIV-1 integration landscape during latent and active infection
-
Cohn LB, Silva IT, Oliveira TY, Rosales RA, Parrish EH, Learn GH, Hahn BH, Czartoski JL, McElrath MJ, Lehmann C, et al. 2015. HIV-1 integration landscape during latent and active infection. Cell 160: 420-432.
-
(2015)
Cell
, vol.160
, pp. 420-432
-
-
Cohn, L.B.1
Silva, I.T.2
Oliveira, T.Y.3
Rosales, R.A.4
Parrish, E.H.5
Learn, G.H.6
Hahn, B.H.7
Czartoski, J.L.8
McElrath, M.J.9
Lehmann, C.10
-
10
-
-
0033180615
-
Coupling of transcription with alternative splicing: RNA Pol II promoters modulate SF2/ASF and 9G8 effects on an exonic splicing enhancer
-
Cramer P, Caceres JF, Cazalla D, Kadener S, Muro AF, Baralle FE, Kornblihtt AR. 1999. Coupling of transcription with alternative splicing: RNA Pol II promoters modulate SF2/ASF and 9G8 effects on an exonic splicing enhancer. Mol Cell 4: 251-258.
-
(1999)
Mol Cell
, vol.4
, pp. 251-258
-
-
Cramer, P.1
Caceres, J.F.2
Cazalla, D.3
Kadener, S.4
Muro, A.F.5
Baralle, F.E.6
Kornblihtt, A.R.7
-
11
-
-
85044706565
-
The RNA polymerase C-terminal domain: A new role in spliceosome assembly
-
David CJ, Manley JL. 2011. The RNA polymerase C-terminal domain: a new role in spliceosome assembly. Transcription 2: 221-225.
-
(2011)
Transcription
, vol.2
, pp. 221-225
-
-
David, C.J.1
Manley, J.L.2
-
12
-
-
0141888375
-
A slow RNA polymerase II affects alternative splicing in vivo
-
de la Mata M, Alonso CR, Kadener S, Fededa JP, Blaustein M, Pelisch F, Cramer P, Bentley D, Kornblihtt AR. 2003. A slow RNA polymerase II affects alternative splicing in vivo. Mol Cell 12: 525-532.
-
(2003)
Mol Cell
, vol.12
, pp. 525-532
-
-
De La Mata, M.1
Alonso, C.R.2
Kadener, S.3
Fededa, J.P.4
Blaustein, M.5
Pelisch, F.6
Cramer, P.7
Bentley, D.8
Kornblihtt, A.R.9
-
13
-
-
84896982583
-
Enhancers are major targets for murine leukemia virus vector integration
-
De Ravin SS, Su L, Theobald N, Choi U, Macpherson JL, Poidinger M, Symonds G, Pond SM, Ferris AL, Hughes SH, et al. 2014. Enhancers are major targets for murine leukemia virus vector integration. J Virol 88: 4504-4513.
-
(2014)
J Virol
, vol.88
, pp. 4504-4513
-
-
De Ravin, S.S.1
Su, L.2
Theobald, N.3
Choi, U.4
Macpherson, J.L.5
Poidinger, M.6
Symonds, G.7
Pond, S.M.8
Ferris, A.L.9
Hughes, S.H.10
-
14
-
-
84888437641
-
The BET family of proteins targets moloney murine leukemia virus integration near transcription start sites
-
De Rijck J, de Kogel C, Demeulemeester J, Vets S, El Ashkar S, Malani N, Bushman FD, Landuyt B, Husson SJ, Busschots K, et al. 2013. The BET family of proteins targets moloney murine leukemia virus integration near transcription start sites. Cell Rep 5: 886-894.
-
(2013)
Cell Rep
, vol.5
, pp. 886-894
-
-
De Rijck, J.1
De Kogel, C.2
Demeulemeester, J.3
Vets, S.4
El Ashkar, S.5
Malani, N.6
Bushman, F.D.7
Landuyt, B.8
Husson, S.J.9
Busschots, K.10
-
15
-
-
84876027348
-
Structural basis for high-affinity binding of LEDGF PWWP to mononucleosomes
-
Eidahl JO, Crowe BL, North JA, McKee CJ, Shkriabai N, Feng L, Plumb M, Graham RL, Gorelick RJ, Hess S, et al. 2013. Structural basis for high-affinity binding of LEDGF PWWP to mononucleosomes. Nucleic Acids Res 41: 3924-3936.
-
(2013)
Nucleic Acids Res
, vol.41
, pp. 3924-3936
-
-
Eidahl, J.O.1
Crowe, B.L.2
North, J.A.3
McKee, C.J.4
Shkriabai, N.5
Feng, L.6
Plumb, M.7
Graham, R.L.8
Gorelick, R.J.9
Hess, S.10
-
16
-
-
84907224797
-
TALEN knockout of the PSIP1 gene in human cells: Analyses of HIV-1 replication and allosteric integrase inhibitor mechanism
-
Fadel HJ, Morrison JH, Saenz DT, Fuchs JR, Kvaratskhelia M, Ekker SC, Poeschla EM. 2014. TALEN knockout of the PSIP1 gene in human cells: analyses of HIV-1 replication and allosteric integrase inhibitor mechanism. J Virol 88: 9704-9717.
-
(2014)
J Virol
, vol.88
, pp. 9704-9717
-
-
Fadel, H.J.1
Morrison, J.H.2
Saenz, D.T.3
Fuchs, J.R.4
Kvaratskhelia, M.5
Ekker, S.C.6
Poeschla, E.M.7
-
17
-
-
77649259825
-
Lens epithelium-derived growth factor fusion proteins redirect HIV-1 DNA integration
-
Ferris AL, Wu X, Hughes CM, Stewart C, Smith SJ, Milne TA, Wang GG, Shun MC, Allis CD, Engelman A, et al. 2010. Lens epithelium-derived growth factor fusion proteins redirect HIV-1 DNA integration. Proc Natl Acad Sci 107: 3135-3140.
-
(2010)
Proc Natl Acad Sci
, vol.107
, pp. 3135-3140
-
-
Ferris, A.L.1
Wu, X.2
Hughes, C.M.3
Stewart, C.4
Smith, S.J.5
Milne, T.A.6
Wang, G.G.7
Shun, M.C.8
Allis, C.D.9
Engelman, A.10
-
18
-
-
84946040120
-
COSMIC: Exploring the world’s knowledge of somatic mutations in human cancer
-
Forbes SA, Beare D, Gunasekaran P, Leung K, Bindal N, Boutselakis H, Ding M, Bamford S, Cole C, Ward S, et al. 2014. COSMIC: exploring the world’s knowledge of somatic mutations in human cancer. Nucleic Acids Res 43: D805-D811.
-
(2014)
Nucleic Acids Res
, vol.43
, pp. D805-D811
-
-
Forbes, S.A.1
Beare, D.2
Gunasekaran, P.3
Leung, K.4
Bindal, N.5
Boutselakis, H.6
Ding, M.7
Bamford, S.8
Cole, C.9
Ward, S.10
-
19
-
-
1542515338
-
A census of human cancer genes
-
Futreal PA, Coin L, Marshall M, Down T, Hubbard T, Wooster R, Rahman N, Stratton MR. 2004. A census of human cancer genes. Nat Rev Cancer 4: 177-183.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 177-183
-
-
Futreal, P.A.1
Coin, L.2
Marshall, M.3
Down, T.4
Hubbard, T.5
Wooster, R.6
Rahman, N.7
Stratton, M.R.8
-
20
-
-
0032239750
-
A novel transcriptional coactivator, p52, functionally interacts with the essential splicing factor ASF/SF2
-
Ge H, Si Y, Wolffe AP. 1998. A novel transcriptional coactivator, p52, functionally interacts with the essential splicing factor ASF/SF2. Mol Cell 2: 751-759.
-
(1998)
Mol Cell
, vol.2
, pp. 751-759
-
-
Ge, H.1
Si, Y.2
Wolffe, A.P.3
-
21
-
-
77649250416
-
LEDGF hybrids efficiently retarget lentiviral integration into heterochromatin
-
Gijsbers R, Ronen K, Vets S, Malani N, De Rijck J, McNeely M, Bushman FD, Debyser Z. 2010. LEDGF hybrids efficiently retarget lentiviral integration into heterochromatin. Mol Ther 18: 552-560.
-
(2010)
Mol Ther
, vol.18
, pp. 552-560
-
-
Gijsbers, R.1
Ronen, K.2
Vets, S.3
Malani, N.4
De Rijck, J.5
McNeely, M.6
Bushman, F.D.7
Debyser, Z.8
-
22
-
-
82355171876
-
Role of the PWWP domain of lens epithelium-derived growth factor (LEDGF)/p75 cofactor in lentiviral integration targeting
-
Gijsbers R, Vets S, De Rijck J, Ocwieja KE, Ronen K, Malani N, Bushman FD, Debyser Z. 2011. Role of the PWWP domain of lens epithelium-derived growth factor (LEDGF)/p75 cofactor in lentiviral integration targeting. J Biol Chem 286: 41812-41825.
-
(2011)
J Biol Chem
, vol.286
, pp. 41812-41825
-
-
Gijsbers, R.1
Vets, S.2
De Rijck, J.3
Ocwieja, K.E.4
Ronen, K.5
Malani, N.6
Bushman, F.D.7
Debyser, Z.8
-
23
-
-
84887146788
-
Bromo and ET domain (BET) chromatin regulators serve as co-factors for murine leukemia virus integration
-
Gupta SS, Maetzig T, Maertens GN, Sharif A, Rothe M, Weidner-Glunde M, Galla M, Schambach A, Cherepanov P, Schulz TF. 2013. Bromo and ET domain (BET) chromatin regulators serve as co-factors for murine leukemia virus integration. J Virol 87: 12721-12736.
-
(2013)
J Virol
, vol.87
, pp. 12721-12736
-
-
Gupta, S.S.1
Maetzig, T.2
Maertens, G.N.3
Sharif, A.4
Rothe, M.5
Weidner-Glunde, M.6
Galla, M.7
Schambach, A.8
Cherepanov, P.9
Schulz, T.F.10
-
24
-
-
0142084745
-
LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1
-
Hacein-Bey-Abina S, Von Kalle C, Schmidt M, McCormack MP, Wulffraat N, Leboulch P, Lim A, Osborne CS, Pawliuk R, Morillon E, et al. 2003. LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1. Science 302: 415-419.
-
(2003)
Science
, vol.302
, pp. 415-419
-
-
Hacein Bey abina, S.1
Von Kalle, C.2
Schmidt, M.3
McCormack, M.P.4
Wulffraat, N.5
Leboulch, P.6
Lim, A.7
Osborne, C.S.8
Pawliuk, R.9
Morillon, E.10
-
25
-
-
77954833516
-
Efficacy of gene therapy for X-linked severe combined immunodeficiency
-
Hacein-Bey-Abina S, Hauer J, Lim A, Picard C, Wang GP, Berry CC, Martinache C, Rieux-Laucat F, Latour S, Belohradsky BH, et al. 2010. Efficacy of gene therapy for X-linked severe combined immunodeficiency. N Engl J Med 363: 355-364.
-
(2010)
N Engl J Med
, vol.363
, pp. 355-364
-
-
Hacein Bey abina, S.1
Hauer, J.2
Lim, A.3
Picard, C.4
Wang, G.P.5
Berry, C.C.6
Martinache, C.7
Rieux-Laucat, F.8
Latour, S.9
Belohradsky, B.H.10
-
26
-
-
61449172037
-
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
-
Huang DW, Sherman BT, Lempicki RA. 2009a. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc 4: 44-57.
-
(2009)
Nat Protoc
, vol.4
, pp. 44-57
-
-
Huang, D.W.1
Sherman, B.T.2
Lempicki, R.A.3
-
27
-
-
58549112996
-
Bioinformatics enrichment tools: Paths toward the comprehensive functional analysis of large gene lists
-
Huang DW, Sherman BT, Lempicki RA. 2009b. Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists. Nucleic Acids Res 37: 1-13.
-
(2009)
Nucleic Acids Res
, vol.37
, pp. 1-13
-
-
Huang, D.W.1
Sherman, B.T.2
Lempicki, R.A.3
-
28
-
-
84885735554
-
Mutational landscape and significance across 12 major cancer types
-
Kandoth C, McLellan MD, Vandin F, Ye K, Niu B, Lu C, Xie M, Zhang Q, McMichael JF, Wyczalkowski MA, et al. 2013. Mutational landscape and significance across 12 major cancer types. Nature 502: 333-339.
-
(2013)
Nature
, vol.502
, pp. 333-339
-
-
Kandoth, C.1
McLellan, M.D.2
Vandin, F.3
Ye, K.4
Niu, B.5
Lu, C.6
Xie, M.7
Zhang, Q.8
McMichael, J.F.9
Wyczalkowski, M.A.10
-
29
-
-
78649714014
-
Analysis and design of RNA sequencing experiments for identifying isoform regulation
-
Katz Y, Wang ET, Airoldi EM, Burge CB. 2010. Analysis and design of RNA sequencing experiments for identifying isoform regulation. Nat Methods 7: 1009-1015.
-
(2010)
Nat Methods
, vol.7
, pp. 1009-1015
-
-
Katz, Y.1
Wang, E.T.2
Airoldi, E.M.3
Burge, C.B.4
-
30
-
-
84887030173
-
Gene therapy on the move
-
Kaufmann KB, Büning H, Galy A, Schambach A, Grez M. 2013. Gene therapy on the move. EMBO Mol Med 5: 1642-1661.
-
(2013)
EMBO Mol Med
, vol.5
, pp. 1642-1661
-
-
Kaufmann, K.B.1
Büning, H.2
Galy, A.3
Schambach, A.4
Grez, M.5
-
31
-
-
84871962937
-
Differential effects of human immunodeficiency virus type 1 capsid and cellular factors nucleoporin 153 and LEDGF/p75 on the efficiency and specificity of viral DNA integration
-
Koh Y, Wu X, Ferris AL, Matreyek KA, Smith SJ, Lee K, KewalRamani VN, Hughes SH, Engelman A. 2013. Differential effects of human immunodeficiency virus type 1 capsid and cellular factors nucleoporin 153 and LEDGF/p75 on the efficiency and specificity of viral DNA integration. J Virol 87: 648-658.
-
(2013)
J Virol
, vol.87
, pp. 648-658
-
-
Koh, Y.1
Wu, X.2
Ferris, A.L.3
Matreyek, K.A.4
Smith, S.J.5
Lee, K.6
Kewalramani, V.N.7
Hughes, S.H.8
Engelman, A.9
-
32
-
-
4644334742
-
Multiple links between transcription and splicing
-
Kornblihtt AR, de la Mata M, Fededa JP, Munoz MJ, Nogues G. 2004. Multiple links between transcription and splicing. RNA 10: 1489-1498.
-
(2004)
RNA
, vol.10
, pp. 1489-1498
-
-
Kornblihtt, A.R.1
De La Mata, M.2
Fededa, J.P.3
Munoz, M.J.4
Nogues, G.5
-
33
-
-
84898976913
-
MLV integration site selection is driven by strong enhancers and active promoters
-
LaFave MC, Varshney GK, Gildea DE, Wolfsberg TG, Baxevanis AD, Burgess SM. 2014. MLV integration site selection is driven by strong enhancers and active promoters. Nucleic Acids Res 42: 4257-4269.
-
(2014)
Nucleic Acids Res
, vol.42
, pp. 4257-4269
-
-
Lafave, M.C.1
Varshney, G.K.2
Gildea, D.E.3
Wolfsberg, T.G.4
Baxevanis, A.D.5
Burgess, S.M.6
-
34
-
-
33748351186
-
Cotranscriptional coupling of splicing factor recruitment and precursor messenger RNA splicing in mammalian cells
-
Listerman I, Sapra AK, Neugebauer KM. 2006. Cotranscriptional coupling of splicing factor recruitment and precursor messenger RNA splicing in mammalian cells. Nat Struct Mol Biol 13: 815-822.
-
(2006)
Nat Struct Mol Biol
, vol.13
, pp. 815-822
-
-
Listerman, I.1
Sapra, A.K.2
Neugebauer, K.M.3
-
35
-
-
4143092604
-
LEDGF/p75 determines cellular trafficking of diverse lentiviral but not murine oncoretroviral integrase proteins and is a component of functional lentiviral preintegration complexes
-
Llano M, Vanegas M, Fregoso O, Saenz D, Chung S, Peretz M, Poeschla EM. 2004. LEDGF/p75 determines cellular trafficking of diverse lentiviral but not murine oncoretroviral integrase proteins and is a component of functional lentiviral preintegration complexes. J Virol 78: 9524-9537.
-
(2004)
J Virol
, vol.78
, pp. 9524-9537
-
-
Llano, M.1
Vanegas, M.2
Fregoso, O.3
Saenz, D.4
Chung, S.5
Peretz, M.6
Poeschla, E.M.7
-
36
-
-
33750358735
-
An essential role for LEDGF/p75 in HIV integration
-
Llano M, Saenz DT, Meehan A, Wongthida P, Peretz M, Walker WH, Teo W, Poeschla EM. 2006a. An essential role for LEDGF/p75 in HIV integration. Science 314: 461-464.
-
(2006)
Science
, vol.314
, pp. 461-464
-
-
Llano, M.1
Saenz, D.T.2
Meehan, A.3
Wongthida, P.4
Peretz, M.5
Walker, W.H.6
Teo, W.7
Poeschla, E.M.8
-
37
-
-
33745617039
-
Identification and characterization of the chromatin-binding domains of the HIV-1 integrase interactor LEDGF/p75
-
Llano M, Vanegas M, Hutchins N, Thompson D, Delgado S, Poeschla EM. 2006b. Identification and characterization of the chromatin-binding domains of the HIV-1 integrase interactor LEDGF/p75. J Mol Biol 360: 760-773.
-
(2006)
J Mol Biol
, vol.360
, pp. 760-773
-
-
Llano, M.1
Vanegas, M.2
Hutchins, N.3
Thompson, D.4
Delgado, S.5
Poeschla, E.M.6
-
38
-
-
0041856142
-
LEDGF/p75 is essential for nuclear and chromosomal targeting of HIV-1 integrase in human cells
-
Maertens G, Cherepanov P, Pluymers W, Busschots K, De Clercq E, Debyser Z, Engelborghs Y. 2003. LEDGF/p75 is essential for nuclear and chromosomal targeting of HIV-1 integrase in human cells. J Biol Chem 278: 33528-33539.
-
(2003)
J Biol Chem
, vol.278
, pp. 33528-33539
-
-
Maertens, G.1
Cherepanov, P.2
Pluymers, W.3
Busschots, K.4
De Clercq, E.5
Debyser, Z.6
Engelborghs, Y.7
-
39
-
-
78149434355
-
The mechanism of retroviral integration from X-ray structures of its key intermediates
-
Maertens GN, Hare S, Cherepanov P. 2010. The mechanism of retroviral integration from X-ray structures of its key intermediates. Nature 468: 326-329.
-
(2010)
Nature
, vol.468
, pp. 326-329
-
-
Maertens, G.N.1
Hare, S.2
Cherepanov, P.3
-
40
-
-
84904115855
-
HIV latency. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells
-
Maldarelli F, Wu X, Su L, Simonetti FR, Shao W, Hill S, Spindler J, Ferris AL, Mellors JW, Kearney MF, et al. 2014. HIV latency. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science 345: 179-183.
-
(2014)
Science
, vol.345
, pp. 179-183
-
-
Maldarelli, F.1
Wu, X.2
Su, L.3
Simonetti, F.R.4
Shao, W.5
Hill, S.6
Spindler, J.7
Ferris, A.L.8
Mellors, J.W.9
Kearney, M.F.10
-
41
-
-
70049090961
-
LEDGF/p75 proteins with alternative chromatin tethers are functional HIV-1 cofactors
-
Meehan AM, Saenz DT, Morrison JH, Garcia-Rivera JA, Peretz M, Llano M, Poeschla EM. 2009. LEDGF/p75 proteins with alternative chromatin tethers are functional HIV-1 cofactors. PLoS Pathog 57: e1000522.
-
(2009)
Plos Pathog
, vol.57
-
-
Meehan, A.M.1
Saenz, D.T.2
Morrison, J.H.3
Garcia-Rivera, J.A.4
Peretz, M.5
Llano, M.6
Poeschla, E.M.7
-
42
-
-
84901420191
-
Adventures in time and space: Splicing efficiency and RNA polymerase II elongation rate
-
Moehle EA, Braberg H, Krogan NJ, Guthrie C. 2014. Adventures in time and space: splicing efficiency and RNA polymerase II elongation rate. RNA Biol 11: 313-319.
-
(2014)
RNA Biol
, vol.11
, pp. 313-319
-
-
Moehle, E.A.1
Braberg, H.2
Krogan, N.J.3
Guthrie, C.4
-
43
-
-
84894259839
-
TOX4 and NOVA1 proteins are partners of the LEDGF PWWP domain and affect HIV-1 replication
-
Morchikh M, Naughtin M, Di Nunzio F, Xavier J, Charneau P, Jacob Y, Lavigne M. 2013. TOX4 and NOVA1 proteins are partners of the LEDGF PWWP domain and affect HIV-1 replication. PLoS One 8: e81217.
-
(2013)
Plos One
, vol.8
-
-
Morchikh, M.1
Naughtin, M.2
Di Nunzio, F.3
Xavier, J.4
Charneau, P.5
Jacob, Y.6
Lavigne, M.7
-
44
-
-
77956183151
-
The carboxy terminal domain of RNA polymerase II and alternative splicing
-
Munoz MJ, de la Mata M, Kornblihtt AR. 2010. The carboxy terminal domain of RNA polymerase II and alternative splicing. Trends Biochem Sci 35: 497-504.
-
(2010)
Trends Biochem Sci
, vol.35
, pp. 497-504
-
-
Munoz, M.J.1
De La Mata, M.2
Kornblihtt, A.R.3
-
45
-
-
84863654457
-
Psip1/Ledgf p52 binds methylated histone H3K36 and splicing factors and contributes to the regulation of alternative splicing
-
Pradeepa MM, Sutherland HG, Ule J, Grimes GR, Bickmore WA. 2012. Psip1/Ledgf p52 binds methylated histone H3K36 and splicing factors and contributes to the regulation of alternative splicing. PLoS Genet 8: e1002717.
-
(2012)
Plos Genet
, vol.8
-
-
Pradeepa, M.M.1
Sutherland, H.G.2
Ule, J.3
Grimes, G.R.4
Bickmore, W.A.5
-
46
-
-
0026696624
-
Nucleosomes, DNA-binding proteins, and DNA sequence modulate retroviral integration target site selection
-
Pryciak PM, Varmus HE. 1992. Nucleosomes, DNA-binding proteins, and DNA sequence modulate retroviral integration target site selection. Cell 69: 769-780.
-
(1992)
Cell
, vol.69
, pp. 769-780
-
-
Pryciak, P.M.1
Varmus, H.E.2
-
47
-
-
0038699144
-
Coupling transcription, splicing andmRNAexport
-
Reed R. 2003. Coupling transcription, splicing andmRNAexport. Curr Opin Cell Biol 15: 326-331.
-
(2003)
Curr Opin Cell Biol
, vol.15
, pp. 326-331
-
-
Reed, R.1
-
48
-
-
0037162715
-
HIV-1 integration in the human genome favors active genes and local hotspots
-
Schroder AR, Shinn P, Chen H, Berry C, Ecker JR, Bushman F. 2002. HIV-1 integration in the human genome favors active genes and local hotspots. Cell 110: 521-529.
-
(2002)
Cell
, vol.110
, pp. 521-529
-
-
Schroder, A.R.1
Shinn, P.2
Chen, H.3
Berry, C.4
Ecker, J.R.5
Bushman, F.6
-
49
-
-
84880392326
-
BET proteins promote efficient murine leukemia virus integration at transcription start sites
-
Sharma A, Larue RC, Plumb MR, Malani N, Male F, Slaughter A, Kessl JJ, Shkriabai N, Coward E, Aiyer SS, et al. 2013. BET proteins promote efficient murine leukemia virus integration at transcription start sites. Proc Natl Acad Sci 110: 12036-12041.
-
(2013)
Proc Natl Acad Sci
, vol.110
, pp. 12036-12041
-
-
Sharma, A.1
Larue, R.C.2
Plumb, M.R.3
Malani, N.4
Male, F.5
Slaughter, A.6
Kessl, J.J.7
Shkriabai, N.8
Coward, E.9
Aiyer, S.S.10
-
50
-
-
34447513231
-
LEDGF/p75 functions downstream from preintegration complex formation to effect gene-specific HIV-1 integration
-
Shun MC, Raghavendra NK, Vandegraaff N, Daigle JE, Hughes S, Kellam P, Cherepanov P, Engelman A. 2007. LEDGF/p75 functions downstream from preintegration complex formation to effect gene-specific HIV-1 integration. Genes Dev 21: 1767-1778.
-
(2007)
Genes Dev
, vol.21
, pp. 1767-1778
-
-
Shun, M.C.1
Raghavendra, N.K.2
Vandegraaff, N.3
Daigle, J.E.4
Hughes, S.5
Kellam, P.6
Cherepanov, P.7
Engelman, A.8
-
51
-
-
33645528413
-
A tripartite DNA-binding element, comprised of the nuclear localization signal and two AT-hook motifs, mediates the association of LEDGF/p75 with chromatin in vivo
-
Turlure F, Maertens G, Rahman S, Cherepanov P, Engelman A. 2006.A tripartite DNA-binding element, comprised of the nuclear localization signal and two AT-hook motifs, mediates the association of LEDGF/p75 with chromatin in vivo. Nucleic Acids Res 34: 1653-1665.
-
(2006)
Nucleic Acids Res
, vol.34
, pp. 1653-1665
-
-
Turlure, F.1
Maertens, G.2
Rahman, S.3
Cherepanov, P.4
Engelman, A.5
-
52
-
-
32444439020
-
Transient and stable knockdown of the integrase cofactor LEDGF/p75 reveals its role in the replication cycle of human immunodeficiency virus
-
Vandekerckhove L, Christ F, Van Maele B, De Rijck J, Gijsbers R, Van den Haute C, Witvrouw M, Debyser Z. 2006. Transient and stable knockdown of the integrase cofactor LEDGF/p75 reveals its role in the replication cycle of human immunodeficiency virus. J Virol 80: 1886-1896.
-
(2006)
J Virol
, vol.80
, pp. 1886-1896
-
-
Vandekerckhove, L.1
Christ, F.2
Van Maele, B.3
De Rijck, J.4
Gijsbers, R.5
Van Den Haute, C.6
Witvrouw, M.7
Debyser, Z.8
-
53
-
-
84875490185
-
Cancer genome landscapes
-
Vogelstein B, Papadopoulos N, Velculescu VE, Zhou S, Diaz LA Jr, Kinzler KW. 2013. Cancer genome landscapes. Science 339: 1546-1558.
-
(2013)
Science
, vol.339
, pp. 1546-1558
-
-
Vogelstein, B.1
Papadopoulos, N.2
Velculescu, V.E.3
Zhou, S.4
Diaz, L.A.5
Kinzler, K.W.6
-
54
-
-
84905917318
-
HIV latency. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection
-
Wagner TA, McLaughlin S, Garg K, Cheung CY, Larsen BB, Styrchak S, Huang HC, Edlefsen PT, Mullins JI, Frenkel LM. 2014. HIV latency. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science 345: 570-573.
-
(2014)
Science
, vol.345
, pp. 570-573
-
-
Wagner, T.A.1
McLaughlin, S.2
Garg, K.3
Cheung, C.Y.4
Larsen, B.B.5
Styrchak, S.6
Huang, H.C.7
Edlefsen, P.T.8
Mullins, J.I.9
Frenkel, L.M.10
-
55
-
-
34547635063
-
HIV integration site selection: Analysis by massively parallel pyrosequencing reveals association with epigenetic modifications
-
Wang GP, Ciuffi A, Leipzig J, Berry CC, Bushman FD. 2007. HIV integration site selection: analysis by massively parallel pyrosequencing reveals association with epigenetic modifications. Genome Res 17: 1186-1194.
-
(2007)
Genome Res
, vol.17
, pp. 1186-1194
-
-
Wang, G.P.1
Ciuffi, A.2
Leipzig, J.3
Berry, C.C.4
Bushman, F.D.5
-
56
-
-
84871220094
-
HRP2 determines the efficiency and specificity of HIV-1 integration in LEDGF/p75 knockout cells but does not contribute to the antiviral activity of a potent LEDGF/p75-binding site integrase inhibitor
-
Wang H, Jurado KA, Wu X, Shun MC, Li X, Ferris AL, Smith SJ, Patel PA, Fuchs JR, Cherepanov P, et al. 2012. HRP2 determines the efficiency and specificity of HIV-1 integration in LEDGF/p75 knockout cells but does not contribute to the antiviral activity of a potent LEDGF/p75-binding site integrase inhibitor. Nucleic Acids Res 40: 11518-11530.
-
(2012)
Nucleic Acids Res
, vol.40
, pp. 11518-11530
-
-
Wang, H.1
Jurado, K.A.2
Wu, X.3
Shun, M.C.4
Li, X.5
Ferris, A.L.6
Smith, S.J.7
Patel, P.A.8
Fuchs, J.R.9
Cherepanov, P.10
-
57
-
-
0037841763
-
Transcription start regions in the human genome are favored targets for MLV integration
-
Wu XL, Li Y, Crise B, Burgess SM. 2003. Transcription start regions in the human genome are favored targets for MLV integration. Science 300: 1749-1751.
-
(2003)
Science
, vol.300
, pp. 1749-1751
-
-
Wu, X.L.1
Li, Y.2
Crise, B.3
Burgess, S.M.4
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