Use and abuse of RNAi to study mammalian gene function

Science

Volumn 337, Issue 6093, 2012, Pages 421-422

  Kaelin, William G ^a  

^a DANA FARBER CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SHORT HAIRPIN RNA; SMALL INTERFERING RNA;

EXPERIMENTAL STUDY; MAMMAL; RNA;

ALGORITHM; AMPLICON; BACTERIAL ARTIFICIAL CHROMOSOME; CELL PROLIFERATION; CELL VIABILITY; DRUG TARGETING; GENE FUNCTION; GENE OVEREXPRESSION; GENE SILENCING; GENE TARGETING; GENETIC ANALYSIS; GENETIC SCREENING; HOMOLOGOUS RECOMBINATION; MAMMAL; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; REVIEW; RNA INTERFERENCE; SOMATIC CELL; ANIMAL; ARTICLE; GENE; GENETICS; HIGH THROUGHPUT SCREENING; HUMAN; METHODOLOGY; PHYSIOLOGY; STANDARD;

MAMMALIA;

ALGORITHMS; ANIMALS; GENE KNOCKDOWN TECHNIQUES; GENE TARGETING; GENES; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; MAMMALS; PHENOTYPE; RNA INTERFERENCE; RNA, SMALL INTERFERING;

EID: 84864326893     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1225787     Document Type: Review

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