A forward genetic screen identifies erythrocyte CD55 as essential for Plasmodium falciparum invasion

Science

Volumn 348, Issue 6235, 2015, Pages 711-714

  Egan, Elizabeth S ^a,b   Jiang, Rays H Y ^a,c   Moechtar, Mischka A ^a   Barteneva, Natasha S ^b   Weekes, Michael P ^d   Nobre, Luis V ^d   Gygi, Steven P ^e   Paulo, Joao A ^e   Frantzreb, Charles ^a   Tani, Yoshihiko ^f   Takahashi, Junko ^f   Watanabe, Seishi ^g   Goldberg, Jonathan ^a   Paul, Aditya S ^a   Brugnara, Carlo ^b   Root, David E ^h   Wiegand, Roger C ^h,i   Doench, John G ^h   Duraisingh, Manoj T ^a,h  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c UNIVERSITY OF SOUTH FLORIDA   (United States)

^d UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^e HARVARD MEDICAL SCHOOL   (United States)

^f Japanese Red Cross Kinki Block Blood Center   (Japan)

^g Japanese Red Cross Kyushu Block Blood Center   (Japan)

^h MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

ⁱ Preceres   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DECAY ACCELERATING FACTOR; HOST FACTOR; CD44 PROTEIN, HUMAN; HERMES ANTIGEN; SMALL INTERFERING RNA;

BLOOD; CYTOLOGY; INVASIVE SPECIES; MALARIA; PATHOGENICITY;

ARTICLE; CONTROLLED STUDY; ERYTHROCYTE; ERYTHROCYTE CULTURE; ERYTHROCYTE MEMBRANE; GENETIC MANIPULATION; GENETIC SCREENING; HEMATOPOIETIC STEM CELL; HOST; HUMAN; HUMAN CELL; MALARIA; PATHOGENESIS; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; ANIMAL; CELL CULTURE; CELL DIFFERENTIATION; CYTOLOGY; GENETICS; HOST PARASITE INTERACTION; MALARIA FALCIPARUM; METABOLISM; PARASITOLOGY; PATHOGENICITY;

PLASMODIUM FALCIPARUM;

ANIMALS; ANTIGENS, CD44; ANTIGENS, CD55; CELL DIFFERENTIATION; CELLS, CULTURED; ERYTHROCYTES; GENETIC TESTING; HEMATOPOIETIC STEM CELLS; HOST-PARASITE INTERACTIONS; HUMANS; MALARIA, FALCIPARUM; PLASMODIUM FALCIPARUM; RNA, SMALL INTERFERING;

EID: 84929207224     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aaa3526     Document Type: Article

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