메뉴 건너뛰기




Volumn 3, Issue 12, 2015, Pages

Altered intrinsic and network properties of neocortical neurons in the Ts65Dn mouse model of down syndrome

Author keywords

Down syndrome; Electrophysiology; Neocortex; Network; Sensory; Trisomy; Ts65Dn; Up states

Indexed keywords

ANIMAL MODEL; ARTICLE; BRAIN DEPTH STIMULATION; BRAIN ELECTROPHYSIOLOGY; CONTROLLED STUDY; DOWN SYNDROME; EXCITATORY POSTSYNAPTIC POTENTIAL; GENOTYPE; INHIBITORY POSTSYNAPTIC POTENTIAL; LATENT PERIOD; MOUSE; NEOCORTEX; NERVE CELL NETWORK; NONHUMAN; OLIGODENDROGLIA; PLOIDY; SOMATOSENSORY CORTEX; SYNAPTIC TRANSMISSION; THALAMUS VENTRAL NUCLEUS; TRISOMY;

EID: 85005995805     PISSN: None     EISSN: 2051817X     Source Type: Journal    
DOI: 10.14814/phy2.12655     Document Type: Article
Times cited : (18)

References (74)
  • 1
    • 0025829803 scopus 로고
    • Thalamocortical responses of mouse somatosensory (Barrel) cortexin vitro
    • Agmon, A., and B. W. Connors. 1991. Thalamocortical responses of mouse somatosensory (barrel) cortexin vitro. Neuroscience 41:365–379.
    • (1991) Neuroscience , vol.41 , pp. 365-379
    • Agmon, A.1    Connors, B.W.2
  • 2
    • 0029952615 scopus 로고    scopus 로고
    • Functional GABAergic synaptic connection in neonatal mouse barrel cortex
    • Agmon, A., G. Hollrigel, and D. K. O’Dowd. 1996. Functional GABAergic synaptic connection in neonatal mouse barrel cortex. J. Neurosci. 16:4684–4695.
    • (1996) J. Neurosci , vol.16 , pp. 4684-4695
    • Agmon, A.1    Hollrigel, G.2    O’Dowd, D.K.3
  • 3
    • 69749110020 scopus 로고    scopus 로고
    • Inter-hemispheric functional coupling of eyes-closed resting EEG rhythms in adolescents with Down syndrome
    • Babiloni, C., G. Albertini, P. Onorati, F. Vecchio, P. Buffo, M. Sará, et al. 2009. Inter-hemispheric functional coupling of eyes-closed resting EEG rhythms in adolescents with Down syndrome. Clin. Neurophysiol. 120:1619–1627.
    • (2009) Neurophysiol , vol.120 , pp. 1619-1627
    • Babiloni, C.1    Albertini, G.2    Onorati, P.3    Vecchio, F.4    Buffo, P.5    Sará, M.6
  • 4
    • 84892607439 scopus 로고    scopus 로고
    • Does stimulus complexity determine whether working memory storage relies on prefrontal or sensory cortex?
    • Bancroft, T. D., W. E. Hockley, and P. Servos. 2014. Does stimulus complexity determine whether working memory storage relies on prefrontal or sensory cortex? Atten Percept Psychophys 76:1954–1961.
    • (2014) Atten Percept Psychophys , vol.76 , pp. 1954-1961
    • Bancroft, T.D.1    Hockley, W.E.2    Servos, P.3
  • 6
    • 34548795562 scopus 로고    scopus 로고
    • Synaptic and cognitive abnormalities in mouse models of Down syndrome: Exploring genotype-phenotype relationships
    • Belichenko, P. V., A. M. Kleschevnikov, A. Salehi, C. J. Epstein, and W. C. Mobley. 2007. Synaptic and cognitive abnormalities in mouse models of Down syndrome: exploring genotype-phenotype relationships. J. Comp. Neurol. 504:329–345.
    • (2007) J. Comp. Neurol , vol.504 , pp. 329-345
    • Belichenko, P.V.1    Kleschevnikov, A.M.2    Salehi, A.3    Epstein, C.J.4    Mobley, W.C.5
  • 7
    • 65949098892 scopus 로고    scopus 로고
    • The “Down syndrome critical region” is sufficient in the mouse model to confer behavioral, neurophysiological, and synaptic phenotypes characteristic of Down syndrome
    • Belichenko, N. P., P. V. Belichenko, A. M. Kleschevnikov, A. Salehi, R. H. Reeves, and W. C. Mobley. 2009a. The “Down syndrome critical region” is sufficient in the mouse model to confer behavioral, neurophysiological, and synaptic phenotypes characteristic of Down syndrome. J. Neurosci. 29:5938–5948.
    • (2009) J. Neurosci , vol.29 , pp. 5938-5948
    • Belichenko, N.P.1    Belichenko, P.V.2    Kleschevnikov, A.M.3    Salehi, A.4    Reeves, R.H.5    Mobley, W.C.6
  • 8
  • 9
    • 33846404179 scopus 로고    scopus 로고
    • Ts65Dn, a mouse model of Down syndrome, exhibits increased GABAB-induced potassium current
    • Best, T. K., R. J. Siarey, and Z. Galdzicki. 2007. Ts65Dn, a mouse model of Down syndrome, exhibits increased GABAB-induced potassium current. J. Neurophysiol. 97:892–900.
    • (2007) J. Neurophysiol , vol.97 , pp. 892-900
    • Best, T.K.1    Siarey, R.J.2    Galdzicki, Z.3
  • 10
    • 84856535551 scopus 로고    scopus 로고
    • Dysfunctional hippocampal inhibition in the Ts65Dn mouse model of Down syndrome
    • Best, T. K., N. P. Cramer, L. Chakrabarti, T. F. Haydar, and Z. Galdzicki. 2012. Dysfunctional hippocampal inhibition in the Ts65Dn mouse model of Down syndrome. Exp. Neurol. 233:749–757.
    • (2012) Exp. Neurol , vol.233 , pp. 749-757
    • Best, T.K.1    Cramer, N.P.2    Chakrabarti, L.3    Haydar, T.F.4    Galdzicki, Z.5
  • 11
    • 77958044278 scopus 로고    scopus 로고
    • Reported sensory processing of children with Down syndrome
    • Bruni, M., D. Cameron, S. Dua, and S. Noy. 2010. Reported sensory processing of children with Down syndrome. Phys Occup Ther Pediatr 30:280–293.
    • (2010) Phys Occup Ther Pediatr , vol.30 , pp. 280-293
    • Bruni, M.1    Cameron, D.2    Dua, S.3    Noy, S.4
  • 13
    • 0031816057 scopus 로고    scopus 로고
    • Matching patterns of activity in primate prefrontal area 8a and parietal area 7ip neurons during a spatial working memory task
    • Chafee, M. V., and P. S. Goldman-Rakic. 1998. Matching patterns of activity in primate prefrontal area 8a and parietal area 7ip neurons during a spatial working memory task. J. Neurophysiol. 79:2919–2940.
    • (1998) J. Neurophysiol , vol.79 , pp. 2919-2940
    • Chafee, M.V.1    Goldman-Rakic, P.S.2
  • 14
    • 77955037842 scopus 로고    scopus 로고
    • Olig1 and Olig2 triplication causes developmental brain defects in Down syndrome
    • Chakrabarti, L., T. K. Best, N. P. Cramer, R. S. E. Carney, J. T. R. Isaac, Z. Galdzicki, et al. 2010. Olig1 and Olig2 triplication causes developmental brain defects in Down syndrome. Nat. Neurosci. 13:927–934.
    • (2010) Neurosci , vol.13 , pp. 927-934
    • Chakrabarti, L.1    Best, T.K.2    Cramer, N.P.3    Carney, R.S.E.4    Isaac, J.T.R.5    Galdzicki, Z.6
  • 15
    • 0034051286 scopus 로고    scopus 로고
    • Behavioral phenotype of individuals with Down syndrome
    • Chapman, R. S., and L. J. Hesketh. 2000. Behavioral phenotype of individuals with Down syndrome. Ment Retard Dev Disabil Res Rev 6:84–95.
    • (2000) Ment Retard Dev Disabil Res Rev , vol.6 , pp. 84-95
    • Chapman, R.S.1    Hesketh, L.J.2
  • 16
    • 28744438296 scopus 로고    scopus 로고
    • Sensory evoked potentials in infants with Down syndrome
    • Chen, Y.-J., and P.-C. Fang. 2005. Sensory evoked potentials in infants with Down syndrome. Acta Paediatr. 94:1615–1618.
    • (2005) Acta Paediatr , vol.94 , pp. 1615-1618
    • Chen, Y.-J.1    Fang, P.-C.2
  • 17
    • 34548102066 scopus 로고    scopus 로고
    • Cell cycle alteration and decreased cell proliferation in the hippocampal dentate gyrus and in the neocortical germinal matrix of fetuses with Down syndrome and in Ts65Dn mice
    • Contestabile, A., T. Fila, C. Ceccarelli, P. Bonasoni, L. Bonapace, D. Santini, et al. 2007. Cell cycle alteration and decreased cell proliferation in the hippocampal dentate gyrus and in the neocortical germinal matrix of fetuses with Down syndrome and in Ts65Dn mice. Hippocampus 17:665–678.
    • (2007) Hippocampus , vol.17 , pp. 665-678
    • Contestabile, A.1    Fila, T.2    Ceccarelli, C.3    Bonasoni, P.4    Bonapace, L.5    Santini, D.6
  • 18
    • 19544393555 scopus 로고    scopus 로고
    • Deficits in hippocampal CA1 LTP induced by TBS but not HFS in the Ts65Dn mouse: A model of Down syndrome
    • Costa, A. C. S., and M. J. Grybko. 2005. Deficits in hippocampal CA1 LTP induced by TBS but not HFS in the Ts65Dn mouse: a model of Down syndrome. Neurosci. Lett. 382:317–322.
    • (2005) Neurosci. Lett , vol.382 , pp. 317-322
    • Costa, A.C.S.1    Grybko, M.J.2
  • 19
    • 84864932030 scopus 로고    scopus 로고
    • From abnormal hippocampal synaptic plasticity in Down syndrome mouse models to cognitive disability in Down syndrome
    • Cramer, N., and Z. Galdzicki. 2012. From abnormal hippocampal synaptic plasticity in Down syndrome mouse models to cognitive disability in Down syndrome. Neural. Plast. 1–12:2012.
    • (2012) Neural. Plast , vol.2012 , pp. 1-12
    • Cramer, N.1    Galdzicki, Z.2
  • 21
    • 84255182652 scopus 로고    scopus 로고
    • Theta oscillations reflect a putative neural mechanism for human sensorimotor integration
    • Cruikshank, L. C., A. Singhal, M. Hueppelsheuser, and J. B. Caplan. 2012. Theta oscillations reflect a putative neural mechanism for human sensorimotor integration. J. Neurophysiol. 107:65–77.
    • (2012) J. Neurophysiol , vol.107 , pp. 65-77
    • Cruikshank, L.C.1    Singhal, A.2    Hueppelsheuser, M.3    Caplan, J.B.4
  • 22
    • 0033151585 scopus 로고    scopus 로고
    • Spatiotemporal analysis of local field potentials and unit discharges in cat cerebral cortex during natural wake and sleep states
    • Destexhe, A., D. Contreras, and M. Steriade. 1999. Spatiotemporal analysis of local field potentials and unit discharges in cat cerebral cortex during natural wake and sleep states. J. Neurosci. 19:4595–4608.
    • (1999) J. Neurosci , vol.19 , pp. 4595-4608
    • Destexhe, A.1    Contreras, D.2    Steriade, M.3
  • 23
    • 0037662885 scopus 로고    scopus 로고
    • Alterations of neocortical pyramidal cell phenotype in the Ts65Dn mouse model of Down syndrome: Effects of Environmental Enrichment. Cereb
    • Dierssen, M., R. Benavides-Piccione, C. Marténez-Cué, X. Estivill, J. Fl_orez, G. N. Elston, et al. 2003. Alterations of neocortical pyramidal cell phenotype in the Ts65Dn mouse model of Down syndrome: effects of Environmental Enrichment. Cereb. Cortex 13:758–764.
    • (2003) Cortex , vol.13 , pp. 758-764
    • Dierssen, M.1    Benavides-Piccione, R.2    Marténez-Cué, C.3    Estivill, X.4    Fl-Orez, J.5    Elston, G.N.6
  • 24
  • 25
    • 0025296344 scopus 로고
    • Down’s syndrome and Alzheimer’s disease: Dendritic spine counts in the hippocampus
    • Ferrer, I., and F. Gullotta. 1990. Down’s syndrome and Alzheimer’s disease: dendritic spine counts in the hippocampus. Acta Neuropathol. 79:680–685.
    • (1990) Acta Neuropathol , vol.79 , pp. 680-685
    • Ferrer, I.1    Gullotta, F.2
  • 26
    • 67650264268 scopus 로고    scopus 로고
    • Neuronal gamma-band synchronization as a fundamental process in cortical computation
    • Fries, P. 2009. Neuronal gamma-band synchronization as a fundamental process in cortical computation. Annu. Rev. Neurosci. 32:209–224.
    • (2009) Annu. Rev. Neurosci , vol.32 , pp. 209-224
    • Fries, P.1
  • 27
    • 53849100522 scopus 로고    scopus 로고
    • Imbalance of neocortical excitation and inhibition and altered UP states reflect network hyperexcitability in the mouse model of fragile X syndrome
    • Gibson, J. R., A. F. Bartley, S. A. Hays, and K. M. Huber. 2008. Imbalance of neocortical excitation and inhibition and altered UP states reflect network hyperexcitability in the mouse model of fragile X syndrome. J. Neurophysiol. 100:2615–2626.
    • (2008) J. Neurophysiol , vol.100 , pp. 2615-2626
    • Gibson, J.R.1    Bartley, A.F.2    Hays, S.A.3    Huber, K.M.4
  • 28
    • 0028070918 scopus 로고
    • Development of the superior temporal neocortex is anomalous in trisomy 21
    • Golden, J. A., and B. T. Hyman. 1994. Development of the superior temporal neocortex is anomalous in trisomy 21. J. Neuropathol. Exp. Neurol. 53:513–520.
    • (1994) J. Neuropathol. Exp. Neurol , vol.53 , pp. 513-520
    • Golden, J.A.1    Hyman, B.T.2
  • 29
    • 41149164894 scopus 로고    scopus 로고
    • Neurogenesis impairment and increased cell death reduce total neuron number in the hippocampal region of fetuses with Down syndrome
    • Guidi, S., P. Bonasoni, C. Ceccarelli, D. Santini, F. Gualtieri, E. Ciani, et al. 2008. Neurogenesis impairment and increased cell death reduce total neuron number in the hippocampal region of fetuses with Down syndrome. Brain Pathol. 18:180–197.
    • (2008) Brain Pathol , vol.18 , pp. 180-197
    • Guidi, S.1    Bonasoni, P.2    Ceccarelli, C.3    Santini, D.4    Gualtieri, F.5    Ciani, E.6
  • 30
    • 65249132270 scopus 로고    scopus 로고
    • Rapid Neocortical Dynamics: Cellular and Network Mechanisms
    • Haider, B., and D. A. McCormick. 2009. Rapid Neocortical Dynamics: cellular and Network Mechanisms. Neuron 62:171–189.
    • (2009) Neuron , vol.62 , pp. 171-189
    • Haider, B.1    McCormick, D.A.2
  • 31
    • 33646833761 scopus 로고    scopus 로고
    • Neocortical network activity in vivo is generated through a dynamic balance of excitation and inhibition
    • Haider, B., A. Duque, A. R. Hasenstaub, and D. A. McCormick. 2006. Neocortical network activity in vivo is generated through a dynamic balance of excitation and inhibition. J. Neurosci. 26:4535–4545.
    • (2006) J. Neurosci , vol.26 , pp. 4535-4545
    • Haider, B.1    Duque, A.2    Hasenstaub, A.R.3    McCormick, D.A.4
  • 32
    • 34249651674 scopus 로고    scopus 로고
    • Elevated expression of the G-protein-activated inwardly rectifying potassium channel 2 (GIRK2) in cerebellar unipolar brush cells of a Down syndrome mouse model. Cell. Mol
    • Harashima, C., D. M. Jacobowitz, M. Stoffel, L. Chakrabarti, T. F. Haydar, R. J. Siarey, et al. 2006a. Elevated expression of the G-protein-activated inwardly rectifying potassium channel 2 (GIRK2) in cerebellar unipolar brush cells of a Down syndrome mouse model. Cell. Mol. Neurobiol. 26:719–734.
    • (2006) Neurobiol , vol.26 , pp. 719-734
    • Harashima, C.1    Jacobowitz, D.M.2    Stoffel, M.3    Chakrabarti, L.4    Haydar, T.F.5    Siarey, R.J.6
  • 33
    • 30144433373 scopus 로고    scopus 로고
    • Abnormal expression of the G-protein-activated inwardly rectifying potassium channel 2 (GIRK2) in hippocampus, frontal cortex, and substantia nigra of Ts65Dn mouse: A model of Down syndrome
    • Harashima, C., D. M. Jacobowitz, J. Witta, R. C. Borke, T. K. Best, R. J. Siarey, et al. 2006b. Abnormal expression of the G-protein-activated inwardly rectifying potassium channel 2 (GIRK2) in hippocampus, frontal cortex, and substantia nigra of Ts65Dn mouse: a model of Down syndrome. J. Comp. Neurol. 494:815–833.
    • (2006) J. Comp. Neurol , vol.494 , pp. 815-833
    • Harashima, C.1    Jacobowitz, D.M.2    Witta, J.3    Borke, R.C.4    Best, T.K.5    Siarey, R.J.6
  • 34
    • 84856508563 scopus 로고    scopus 로고
    • Trisomy 21 and early brain development
    • Haydar, T. F., and R. H. Reeves. 2012. Trisomy 21 and early brain development. Trends Neurosci. 35:81–91.
    • (2012) Trends Neurosci , vol.35 , pp. 81-91
    • Haydar, T.F.1    Reeves, R.H.2
  • 36
    • 4644250821 scopus 로고    scopus 로고
    • Hippocampal long-term potentiation suppressed by increased inhibition in the Ts65Dn mouse, a genetic model of Down syndrome
    • Kleschevnikov, A. M., P. V. Belichenko, A. J. Villar, C. J. Epstein, R. C. Malenka, and W. C. Mobley. 2004. Hippocampal long-term potentiation suppressed by increased inhibition in the Ts65Dn mouse, a genetic model of Down syndrome. J. Neurosci. 24:8153–8160.
    • (2004) J. Neurosci , vol.24 , pp. 8153-8160
    • Kleschevnikov, A.M.1    Belichenko, P.V.2    Villar, A.J.3    Epstein, C.J.4    Malenka, R.C.5    Mobley, W.C.6
  • 37
    • 84855791494 scopus 로고    scopus 로고
    • Increased efficiency of the GABAA and GABAB receptor-mediated neurotransmission in the Ts65Dn mouse model of Down syndrome. Neurobiol
    • Kleschevnikov, A. M., P. V. Belichenko, J. Gall, L. George, R. Nosheny, M. T. Maloney, et al. 2012. Increased efficiency of the GABAA and GABAB receptor-mediated neurotransmission in the Ts65Dn mouse model of Down syndrome. Neurobiol. Dis. 45:683–691.
    • (2012) Dis , vol.45 , pp. 683-691
    • Kleschevnikov, A.M.1    Belichenko, P.V.2    Gall, J.3    George, L.4    Nosheny, R.5    Maloney, M.T.6
  • 38
    • 84856935541 scopus 로고    scopus 로고
    • Auditory function in the Tc1 mouse model of down syndrome suggests a limited region of human chromosome 21 involved in otitis media
    • Kuhn, S., N. Ingham, S. Pearson, S. M. Gribble, S. Clayton, K. P. Steel, et al. 2012. Auditory function in the Tc1 mouse model of down syndrome suggests a limited region of human chromosome 21 involved in otitis media. PLoS ONE 7:e31433.
    • (2012) Plos ONE , vol.7
    • Kuhn, S.1    Ingham, N.2    Pearson, S.3    Gribble, S.M.4    Clayton, S.5    Steel, K.P.6
  • 39
    • 77449110704 scopus 로고    scopus 로고
    • PCR prescreen for genotyping the Ts65Dn mouse model of Down syndrome
    • Lorenzi, H., N. Duvall, S. M. Cherry, R. H. Reeves, and R. J. Roper. 2010. PCR prescreen for genotyping the Ts65Dn mouse model of Down syndrome. Biotechniques 48:35–38.
    • (2010) Biotechniques , vol.48 , pp. 35-38
    • Lorenzi, H.1    Duvall, N.2    Cherry, S.M.3    Reeves, R.H.4    Roper, R.J.5
  • 40
    • 0015528841 scopus 로고
    • Structural abnormalities of the cerebral cortex in human chromosomal aberrations: A Golgi study
    • Marin-Padilla, M. 1972. Structural abnormalities of the cerebral cortex in human chromosomal aberrations: a Golgi study. Brain Res. 44:625–629.
    • (1972) Brain Res , vol.44 , pp. 625-629
    • Marin-Padilla, M.1
  • 41
    • 0017234871 scopus 로고
    • Pyramidal cell abnormalities in the motor cortex of a child with Down’s syndrome
    • Marin-Padilla, M. 1976. Pyramidal cell abnormalities in the motor cortex of a child with Down’s syndrome. A Golgi Study. J. Comp. Neurol. 167:63–81.
    • (1976) A Golgi Study. J. Comp. Neurol , vol.167 , pp. 63-81
    • Marin-Padilla, M.1
  • 43
    • 18044366812 scopus 로고    scopus 로고
    • Neuronal networks: Flip-flops in the brain
    • McCormick, D. A. 2005. Neuronal networks: flip-flops in the brain. Curr. Biol. 15:R294–R296.
    • (2005) Curr. Biol , vol.15 , pp. R294-R296
    • McCormick, D.A.1
  • 44
    • 79958224719 scopus 로고    scopus 로고
    • Relationship between brain and cognitive processes in Down syndrome
    • Menghini, D., F. Costanzo, and S. Vicari. 2011. Relationship between brain and cognitive processes in Down syndrome. Behav. Genet. 41:381–393.
    • (2011) Behav. Genet , vol.41 , pp. 381-393
    • Menghini, D.1    Costanzo, F.2    Vicari, S.3
  • 45
    • 0029783329 scopus 로고    scopus 로고
    • Neural mechanisms of visual working memory in prefrontal cortex of the macaque
    • Miller, E. K., C. A. Erickson, and R. Desimone. 1996. Neural mechanisms of visual working memory in prefrontal cortex of the macaque. J. Neurosci. 16:5154–5167.
    • (1996) J. Neurosci , vol.16 , pp. 5154-5167
    • Miller, E.K.1    Erickson, C.A.2    Desimone, R.3
  • 46
    • 79955962277 scopus 로고    scopus 로고
    • Neuronal ensemble for visual working memory via interplay of slow and fast oscillations
    • Mizuhara, H., and Y. Yamaguchi. 2011. Neuronal ensemble for visual working memory via interplay of slow and fast oscillations. Eur. J. Neurosci. 33:1925–1934.
    • (2011) Eur. J. Neurosci , vol.33 , pp. 1925-1934
    • Mizuhara, H.1    Yamaguchi, Y.2
  • 47
    • 0026684708 scopus 로고
    • Coherent 25- to 35-Hz oscillations in the sensorimotor cortex of awake behaving monkeys
    • Murthy, V. N., and E. E. Fetz. 1992. Coherent 25- to 35-Hz oscillations in the sensorimotor cortex of awake behaving monkeys. Proc. Natl Acad. Sci. USA 89:5670–5674.
    • (1992) Proc. Natl Acad. Sci. USA , vol.89 , pp. 5670-5674
    • Murthy, V.N.1    Fetz, E.E.2
  • 49
    • 60549091016 scopus 로고    scopus 로고
    • A single standard for memory: The case for reconsolidation
    • Nader, K., and O. Hardt. 2009. A single standard for memory: the case for reconsolidation. Nat. Rev. Neurosci. 10:224–234.
    • (2009) Nat. Rev. Neurosci , vol.10 , pp. 224-234
    • Nader, K.1    Hardt, O.2
  • 50
    • 84867308771 scopus 로고    scopus 로고
    • The neocortical network representing associative memory reorganizes with time in a process engaging the anterior temporal lobe
    • Nieuwenhuis, I. L. C., A. Takashima, R. Oostenveld, B. L. McNaughton, G. Fernández, and O. Jensen. 2012. The neocortical network representing associative memory reorganizes with time in a process engaging the anterior temporal lobe. Cereb. Cortex 22:2622–2633.
    • (2012) Cereb. Cortex , vol.22 , pp. 2622-2633
    • Nieuwenhuis, I.L.C.1    Takashima, A.2    Oostenveld, R.3    McNaughton, B.L.4    Fernández, G.5    Jensen, O.6
  • 51
    • 79955730452 scopus 로고    scopus 로고
    • Localization of cortical phase and amplitude dynamics during visual working memory encoding and retention
    • Palva, S., S. Kulashekhar, M. Hämäläinen, and J. M. Palva. 2011. Localization of cortical phase and amplitude dynamics during visual working memory encoding and retention. J. Neurosci. 31:5013–5025.
    • (2011) J. Neurosci. , vol.31 , pp. 5013-5025
    • Palva, S.1    Kulashekhar, S.2    Hämäläinen, M.3    Palva, J.M.4
  • 52
    • 0038687498 scopus 로고    scopus 로고
    • The neuropsychology of Down syndrome: Evidence for hippocampal dysfunction
    • Pennington, B. F., J. Moon, J. Edgin, J. Stedron, and L. Nadel. 2003. The neuropsychology of Down syndrome: evidence for hippocampal dysfunction. Child Dev. 74:75–93.
    • (2003) Child Dev , vol.74 , pp. 75-93
    • Pennington, B.F.1    Moon, J.2    Edgin, J.3    Stedron, J.4    Nadel, L.5
  • 53
    • 0036321059 scopus 로고    scopus 로고
    • Temporal structure in neuronal activity during working memory in macaque parietal cortex
    • Pesaran, B., J. S. Pezaris, M. Sahani, P. P. Mitra, and R. A. Andersen. 2002. Temporal structure in neuronal activity during working memory in macaque parietal cortex. Nat. Neurosci. 5:805–811.
    • (2002) Nat. Neurosci , vol.5 , pp. 805-811
    • Pesaran, B.1    Pezaris, J.S.2    Sahani, M.3    Mitra, P.P.4    Andersen, R.A.5
  • 54
    • 0035836647 scopus 로고    scopus 로고
    • Amygdala and hippocampal volumes in children with Down syndrome: A high-resolution MRI study
    • Pinter, J. D., W. E. Brown, S. Eliez, J. E. Schmitt, G. T. Capone, and A. L. Reiss. 2001. Amygdala and hippocampal volumes in children with Down syndrome: a high-resolution MRI study. Neurology 56:972–974.
    • (2001) Neurology , vol.56 , pp. 972-974
    • Pinter, J.D.1    Brown, W.E.2    Eliez, S.3    Schmitt, J.E.4    Capone, G.T.5    Reiss, A.L.6
  • 55
    • 33645871604 scopus 로고    scopus 로고
    • Working memory as an emergent property of the mind and brain
    • Postle, B. R. 2006. Working memory as an emergent property of the mind and brain. Neuroscience 139:23–38.
    • (2006) Neuroscience , vol.139 , pp. 23-38
    • Postle, B.R.1
  • 56
    • 0016604372 scopus 로고
    • Normal and aberrant neuronal development in the cerebral cortex of human fetus and young infant
    • Purpura, D. P. 1975. Normal and aberrant neuronal development in the cerebral cortex of human fetus and young infant. UCLA Forum Med Sci 141–169.
    • (1975) UCLA Forum Med Sci , pp. 141-169
    • Purpura, D.P.1
  • 57
    • 84655164829 scopus 로고    scopus 로고
    • Molecular characterization of the translocation breakpoints in the Down syndrome mouse model Ts65Dn
    • Reinholdt, L. G., Y. Ding, G. T. Gilbert, A. Czechanski, J. P. Solzak, R. J. Roper, et al. 2011. Molecular characterization of the translocation breakpoints in the Down syndrome mouse model Ts65Dn. Mamm. Genome 22:685–691.
    • (2011) Mamm. Genome , vol.22 , pp. 685-691
    • Reinholdt, L.G.1    Ding, Y.2    Gilbert, G.T.3    Czechanski, A.4    Solzak, J.P.5    Roper, R.J.6
  • 58
    • 34247360027 scopus 로고    scopus 로고
    • Thalamocortical Up states: Differential effects of intrinsic and extrinsic cortical inputs on persistent activity
    • Rigas, P., and M. A. Castro-Alamancos. 2007. Thalamocortical Up states: differential effects of intrinsic and extrinsic cortical inputs on persistent activity. J. Neurosci. 27:4261–4272.
    • (2007) J. Neurosci , vol.27 , pp. 4261-4272
    • Rigas, P.1    Castro-Alamancos, M.A.2
  • 59
    • 83055165965 scopus 로고    scopus 로고
    • Slow and fast rhythms generated in the cerebral cortex of the anesthetized mouse
    • Ruiz-Mejias, M., L. Ciria-Suarez, M. Mattia, and M. V. Sanchez-Vives. 2011. Slow and fast rhythms generated in the cerebral cortex of the anesthetized mouse. J. Neurophysiol. 106:2910–2921.
    • (2011) J. Neurophysiol , vol.106 , pp. 2910-2921
    • Ruiz-Mejias, M.1    Ciria-Suarez, L.2    Mattia, M.3    Sanchez-Vives, M.V.4
  • 60
    • 0033799036 scopus 로고    scopus 로고
    • Cellular and network mechanisms of rhythmic recurrent activity in neocortex
    • Sanchez-Vives, M. V., and D. A. McCormick. 2000. Cellular and network mechanisms of rhythmic recurrent activity in neocortex. Nat. Neurosci. 3:1027–1034.
    • (2000) Nat. Neurosci , vol.3 , pp. 1027-1034
    • Sanchez-Vives, M.V.1    McCormick, D.A.2
  • 61
    • 0032738081 scopus 로고    scopus 로고
    • Properties of delay-period neuronal activity in the monkey dorsolateral prefrontal cortex during a spatial delayed matching-to-sample task
    • Sawaguchi, T., and I. Yamane. 1999. Properties of delay-period neuronal activity in the monkey dorsolateral prefrontal cortex during a spatial delayed matching-to-sample task. J. Neurophysiol. 82:2070–2080.
    • (1999) J. Neurophysiol , vol.82 , pp. 2070-2080
    • Sawaguchi, T.1    Yamane, I.2
  • 62
    • 77953251323 scopus 로고    scopus 로고
    • The mouse model of Down syndrome Ts65Dn presents visual deficits as assessed by pattern visual evoked potentials
    • Scott-McKean, J. J., B. Chang, R. E. Hurd, S. Nusinowitz, C. Schmidt, M. T. Davisson, et al. 2010. The mouse model of Down syndrome Ts65Dn presents visual deficits as assessed by pattern visual evoked potentials. Invest. Ophthalmol. Vis. Sci. 51:3300–3308.
    • (2010) Invest. Ophthalmol. Vis. Sci , vol.51 , pp. 3300-3308
    • Scott-McKean, J.J.1    Chang, B.2    Hurd, R.E.3    Nusinowitz, S.4    Schmidt, C.5    Davisson, M.T.6
  • 63
    • 0031414807 scopus 로고    scopus 로고
    • Altered long-term potentiation in the young and old Ts65Dn mouse, a model for Down Syndrome
    • Siarey, R. J., J. Stoll, S. I. Rapoport, and Z. Galdzicki. 1997. Altered long-term potentiation in the young and old Ts65Dn mouse, a model for Down Syndrome. Neuropharmacology 36:1549–1554.
    • (1997) Neuropharmacology , vol.36 , pp. 1549-1554
    • Siarey, R.J.1    Stoll, J.2    Rapoport, S.I.3    Galdzicki, Z.4
  • 64
    • 21344435258 scopus 로고    scopus 로고
    • Abnormal synaptic plasticity in the Ts1Cje segmental trisomy 16 mouse model of Down syndrome
    • Siarey, R. J., A. J. Villar, C. J. Epstein, and Z. Galdzicki. 2005. Abnormal synaptic plasticity in the Ts1Cje segmental trisomy 16 mouse model of Down syndrome. Neuropharmacology 49:122–128.
    • (2005) Neuropharmacology , vol.49 , pp. 122-128
    • Siarey, R.J.1    Villar, A.J.2    Epstein, C.J.3    Galdzicki, Z.4
  • 65
    • 33746452680 scopus 로고    scopus 로고
    • Altered signaling pathways underlying abnormal hippocampal synaptic plasticity in the Ts65Dn mouse model of Down syndrome
    • Siarey, R. J., A. Kline-Burgess, M. Cho, A. Balbo, T. K. Best, C. Harashima, et al. 2006. Altered signaling pathways underlying abnormal hippocampal synaptic plasticity in the Ts65Dn mouse model of Down syndrome. J. Neurochem. 98:1266–1277.
    • (2006) J. Neurochem , vol.98 , pp. 1266-1277
    • Siarey, R.J.1    Kline-Burgess, A.2    Cho, M.3    Balbo, A.4    Best, T.K.5    Harashima, C.6
  • 67
    • 0035003185 scopus 로고    scopus 로고
    • Natural waking and sleep states: A view from inside neocortical neurons
    • Steriade, M., I. Timofeev, and F. Grenier. 2001. Natural waking and sleep states: a view from inside neocortical neurons. J. Neurophysiol. 85:1969–1985.
    • (2001) J. Neurophysiol , vol.85 , pp. 1969-1985
    • Steriade, M.1    Timofeev, I.2    Grenier, F.3
  • 68
    • 0018964370 scopus 로고
    • Spine distribution along the apical dendrites of the pyramidal neurons in Down’s syndrome. A quantitative Golgi study
    • Suetsugu, M., and P. Mehraein. 1980. Spine distribution along the apical dendrites of the pyramidal neurons in Down’s syndrome. A quantitative Golgi study. Acta Neuropathol. 50:207–210.
    • (1980) Acta Neuropathol , vol.50 , pp. 207-210
    • Suetsugu, M.1    Mehraein, P.2
  • 69
    • 0021092302 scopus 로고
    • The hippocampus in Down’s syndrome
    • Sylvester, P. E. 1983. The hippocampus in Down’s syndrome. J. Ment. Defic. Res. 27(Pt 3):227–236.
    • (1983) J. Ment. Defic. Res , vol.27 , pp. 227-236
    • Sylvester, P.E.1
  • 71
    • 55849084310 scopus 로고    scopus 로고
    • Spontaneous changes of neocortical code for associative memory during consolidation
    • Takehara-Nishiuchi, K., and B. L. McNaughton. 2008. Spontaneous changes of neocortical code for associative memory during consolidation. Science 322:960–963.
    • (2008) Science , vol.322 , pp. 960-963
    • Takehara-Nishiuchi, K.1    McNaughton, B.L.2
  • 72
    • 84862878470 scopus 로고    scopus 로고
    • Increased excitability and altered action potential waveform in cerebellar granule neurons of the Ts65Dn mouse model of Down syndrome
    • Usowicz, M. M., and C. L. P. Garden. 2012. Increased excitability and altered action potential waveform in cerebellar granule neurons of the Ts65Dn mouse model of Down syndrome. Brain Res. 1465:10–17.
    • (2012) Brain Res , vol.1465 , pp. 10-17
    • Usowicz, M.M.1    Garden, C.L.P.2
  • 73
    • 77954176653 scopus 로고    scopus 로고
    • Memory formation and long-term retention in humans and animals: Convergence towards a transformation account of hippocampal-neocortical interactions
    • Winocur, G., M. Moscovitch, and B. Bontempi. 2010. Memory formation and long-term retention in humans and animals: convergence towards a transformation account of hippocampal-neocortical interactions. Neuropsychologia 48:2339–2356.
    • (2010) Neuropsychologia , vol.48 , pp. 2339-2356
    • Winocur, G.1    Moscovitch, M.2    Bontempi, B.3
  • 74
    • 80053637833 scopus 로고    scopus 로고
    • Correlations of sensory processing and visual organization ability with participation in school-aged children with Down syndrome
    • Wuang, Y.-P., and C.-Y. Su. 2011. Correlations of sensory processing and visual organization ability with participation in school-aged children with Down syndrome. Res. Dev. Disabil. 32:2398–2407.
    • (2011) Res. Dev. Disabil , vol.32 , pp. 2398-2407
    • Wuang, Y.-P.1    Su, C.-Y.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.