CXCR4 increases in-vivo glioma perivascular invasion, and reduces radiation induced apoptosis: A genetic knockdown study

Oncotarget

Volumn 7, Issue 50, 2016, Pages 83701-83719

  Yadav, Viveka Nand ^a   Zamler, Daniel ^a   Baker, Gregory J ^a,b   Kadiyala, Padma ^a   Erdreich Epstein, Anat ^c   DeCarvalho, Ana C ^d   Mikkelsen, Tom ^d   Castro, Maria G ^a   Lowenstein, Pedro R ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c CHILDREN S HOSPITAL LOS ANGELES   (United States)

^d HENRY FORD HOSPITAL   (United States)

Author keywords

Autovascularization; Combination therapies; CXCR4 knockdown; Glioma radiotherapy resistance; Perivascular invasion

Indexed keywords

CASPASE 3; CD31 ANTIGEN; CHEMOKINE RECEPTOR CXCR4; SHORT HAIRPIN RNA; STROMAL CELL DERIVED FACTOR 1; CXCR4 PROTEIN, HUMAN; CXCR4 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN MICROVASCULAR ENDOTHELIAL CELL; CANCER INHIBITION; CANCER RADIOTHERAPY; CANCER SURVIVAL; CAPILLARY ENDOTHELIAL CELL; CELL MIGRATION; CONTROLLED STUDY; DISEASE ASSOCIATION; DOWN REGULATION; FEMALE; GENE EXPRESSION REGULATION; GENE SILENCING; GL26 CIT CELL LINE; GLIOMA; GLIOMA CELL; HF2303 CELL LINE; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; PERIVASCULAR INVASION; PROTEIN FUNCTION; QUANTITATIVE ANALYSIS; RADIATION INDUCED APOPTOSIS; SURVIVAL RATE; SURVIVAL TIME; TREATMENT RESPONSE; TUMOR INVASION; ANIMAL; BRAIN TUMOR; C57BL MOUSE; CANCER STEM CELL; CELL MOTION; CELL PROLIFERATION; COCULTURE; ENDOTHELIUM CELL; GENE KNOCKDOWN; GENETIC TRANSFECTION; GENETICS; GLIOBLASTOMA; METABOLISM; PATHOLOGY; RADIATION RESPONSE; RADIATION TOLERANCE; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TIME FACTOR; TUMOR CELL CULTURE; TUMOR CELL LINE; TUMOR VOLUME;

ANIMALS; APOPTOSIS; BRAIN NEOPLASMS; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; COCULTURE TECHNIQUES; ENDOTHELIAL CELLS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE KNOCKDOWN TECHNIQUES; GLIOBLASTOMA; HUMANS; MICE; MICE, INBRED C57BL; NEOPLASM INVASIVENESS; NEOPLASTIC STEM CELLS; RADIATION TOLERANCE; RECEPTORS, CXCR4; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSFECTION; TUMOR BURDEN; TUMOR CELLS, CULTURED;

EID: 85004001418     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.13295     Document Type: Article

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