A distinct subset of glioma cell lines with stem cell-like properties reflects the transcriptional phenotype of glioblastomas and overexpresses CXCR4 as therapeutic target

GLIA

Volumn 59, Issue 4, 2011, Pages 590-602

  Schulte, Alexander ^a   Günther, Hauke S ^a   Phillips, Heidi S ^b   Kemming, Dirk ^a   Martens, Tobias ^a   Kharbanda, Samir ^b   Soriano, Robert H ^b   Modrusan, Zora ^b   Zapf, Svenja ^a   Westphal, Manfred ^a   Lamszus, Katrin ^a  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^b GENENTECH INC   (United States)

Author keywords

Glioblastoma; Invasion; Microarray; Pathway; Stem cell

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; PLERIXAFOR; TRANSCRIPTOME;

ARTICLE; CANCER INHIBITION; CARCINOGENESIS; CELL MIGRATION; CELL POPULATION; CELL STIMULATION; FLUORESCENCE ACTIVATED CELL SORTING; GENE CONTROL; GENE EXPRESSION; GENE FUNCTION; GENE OVEREXPRESSION; GENE TARGETING; GENETIC TRANSCRIPTION; GLIOBLASTOMA; GLIOMA CELL; HUMAN; HUMAN CELL; IN VIVO STUDY; PHENOTYPE; PRIORITY JOURNAL; STEM CELL; TUMOR GROWTH;

BLOTTING, WESTERN; CELL LINE, TUMOR; CELL MOVEMENT; FLOW CYTOMETRY; GENE EXPRESSION PROFILING; GLIOBLASTOMA; HUMANS; IMMUNOHISTOCHEMISTRY; NEOPLASTIC STEM CELLS; PHENOTYPE; RECEPTORS, CXCR4; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STATISTICS, NONPARAMETRIC; TUMOR CELLS, CULTURED;

EID: 79851501293     PISSN: 08941491     EISSN: 10981136     Source Type: Journal    
DOI: 10.1002/glia.21127     Document Type: Article

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