Reversibility of glioma stem cells' phenotypes explains their complex in vitro and in vivo behavior. Discovery of a novel neurosphere-specific enzyme, cGMP-dependent protein kinase 1, using the genomic landscape of human glioma stem cells as a discovery tool

Oncotarget

Volumn 7, Issue 39, 2016, Pages 63020-63041

  Wilson, Thomas J ^a   Zamler, Daniel B ^a   Doherty, Robert ^a   Castro, Maria G ^a   Lowenstein, Pedro R ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Genomics; Glioblastoma; Plasticity; PRKG1; Stem cells

Indexed keywords

CISPLATIN; CYCLIC GMP DEPENDENT PROTEIN KINASE 1; DOXORUBICIN; MESSENGER RNA; PACLITAXEL; TEMOZOLOMIDE; DACARBAZINE; PRKG1 PROTEIN, HUMAN; TUMOR MARKER;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL INVASION; CELL MIGRATION; CELL PROLIFERATION; CELL SURVIVAL; CELL VIABILITY; CHEMOSENSITIVITY; CHEMOTAXIS; CONTROLLED STUDY; DOWN REGULATION; DRUG INHIBITION; FEMALE; GENE EXPRESSION REGULATION; GENOMICS; GLIOBLASTOMA; GLIOMA STEM CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; PHENOTYPE; PRKG1 GENE; PROTEIN FUNCTION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR CELL CULTURE; UPREGULATION; ANALOGS AND DERIVATIVES; ANIMAL; BRAIN TUMOR; CANCER STEM CELL; CELL MOTION; CHEMISTRY; DNA MICROARRAY; GLIOMA; METABOLISM; NERVE CELL; PATHOLOGY; STEM CELL; TRANSGENIC MOUSE; TUMOR CELL LINE; TUMOR INVASION;

ANIMALS; APOPTOSIS; BIOMARKERS, TUMOR; BRAIN NEOPLASMS; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; CHEMOTAXIS; CYCLIC GMP-DEPENDENT PROTEIN KINASE TYPE I; DACARBAZINE; DOXORUBICIN; FEMALE; GLIOBLASTOMA; GLIOMA; HUMANS; MALE; MICE; MICE, TRANSGENIC; NEOPLASM INVASIVENESS; NEOPLASTIC STEM CELLS; NEURONS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PACLITAXEL; PHENOTYPE; STEM CELLS;

EID: 84994045054     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.11589     Document Type: Article

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