The induction of autophagy against mitochondria-mediated apoptosis in lung cancer cells by a ruthenium (II) imidazole complex

Oncotarget

Volumn 7, Issue 49, 2016, Pages 80716-80734

  Chen, Lanmei ^a   Li, Guodong ^a   Peng, Fa ^a   Jie, Xinming ^a   Dongye, Guangzhi ^a   Cai, Kangrong ^a   Feng, Ruibing ^b   Li, Baojun ^a   Zeng, Qingwang ^a   Lun, Kaiyi ^a   Chen, Jincan ^a   Xu, Bilian ^a  

^a GUANGDONG MEDICAL UNIVERSITY   (China)

^b University of Macau   (Macao)

Author keywords

Apoptosis; Autophagy; Cytotoxicity; Reactive oxygen species; Ruthenium imidazole complex

Indexed keywords

3 METHYLADENINE; ACETYLCYSTEINE; CASPASE 3; CELL PROTEIN; CHLOROQUINE; CISPLATIN; CYTOCHROME C; IMIDAZOLE DERIVATIVE; LC3 II PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; REACTIVE OXYGEN METABOLITE; RUTHENIUM DERIVATIVE; TIRON; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; CASP3 PROTEIN, HUMAN; MAP1LC3A PROTEIN, HUMAN; MICROTUBULE ASSOCIATED PROTEIN; ORGANOMETALLIC COMPOUND; RUTHENIUM;

A549 CELL LINE; ACIDIC VESICULAR ORGANELLE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CANCER CELL; CANCER CELL LINE; CANCER INHIBITION; CELL ORGANELLE; CELL PROTECTION; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DRUG POTENTIATION; DRUG TARGETING; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME RELEASE; FEMALE; HUMAN; HUMAN CELL; IN VIVO STUDY; LUNG CANCER; MOUSE; NCI H460 CELL LINE; NONHUMAN; SIGNAL TRANSDUCTION; TARGET CELL DESTRUCTION; TUMOR XENOGRAFT; UPREGULATION; A-549 CELL LINE; ANIMAL; BAGG ALBINO MOUSE; CELL CYCLE CHECKPOINT; CELL PROLIFERATION; DOSE RESPONSE; DRUG EFFECTS; DRUG SCREENING; LUNG TUMOR; METABOLISM; MITOCHONDRION; NUDE MOUSE; PATHOLOGY; TIME FACTOR; TUMOR VOLUME;

A549 CELLS; ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; AUTOPHAGOSOMES; AUTOPHAGY; CASPASE 3; CELL CYCLE CHECKPOINTS; CELL PROLIFERATION; CYTOCHROMES C; DOSE-RESPONSE RELATIONSHIP, DRUG; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEMALE; HUMANS; IMIDAZOLES; LUNG NEOPLASMS; MICE, INBRED BALB C; MICE, NUDE; MICROTUBULE-ASSOCIATED PROTEINS; MITOCHONDRIA; ORGANOMETALLIC COMPOUNDS; REACTIVE OXYGEN SPECIES; RUTHENIUM; SIGNAL TRANSDUCTION; TIME FACTORS; TUMOR BURDEN; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 85001070787     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.13032     Document Type: Article

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