Ciclopirox induces autophagy through reactive oxygen species-mediated activation of JNK signaling pathway

Oncotarget

Volumn 5, Issue 20, 2014, Pages 10140-10150

  Zhou, Hongyu ^a,b   Shen, Tao ^b   Shang, Chaowei ^b   Luo, Yan ^b   Liu, Lei ^b   Yan, Juming ^a   Li, Yan ^a   Huang, Shile ^b  

^a KUNMING INSTITUTE OF BOTANY   (China)

^b LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

Author keywords

Autophagy; Ciclopirox; JNK; Reactive oxygen species; Rhabdomyosarcoma

Indexed keywords

ACETYLCYSTEINE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CHLOROQUINE; CICLOPIROX; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; ANTIFUNGAL AGENT; ANTINEOPLASTIC AGENT; PYRIDONE DERIVATIVE;

ADENOVIRIDAE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGY; CELL STRUCTURE; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; DRUG POTENTIATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; RD CELL LINE; RH30 CELL LINE; RHABDOMYOSARCOMA CELL LINE; SIGNAL TRANSDUCTION; WESTERN BLOTTING; DRUG EFFECTS; ENZYMOLOGY; METABOLISM; PATHOLOGY; RHABDOMYOSARCOMA; TUMOR CELL LINE;

ANTIFUNGAL AGENTS; ANTINEOPLASTIC AGENTS; AUTOPHAGY; CELL LINE, TUMOR; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MAP KINASE SIGNALING SYSTEM; PYRIDONES; REACTIVE OXYGEN SPECIES; RHABDOMYOSARCOMA;

EID: 84920952690     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.2471     Document Type: Article

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