A non-viral suicide gene delivery system traversing the blood brain barrier for non-invasive glioma targeting treatment

Journal of Controlled Release

Volumn 243, Issue , 2016, Pages 357-369

  Gao, Shiqian ^a,c   Tian, Huayu ^a   Xing, Zhenkai ^b   Zhang, Dawei ^a   Guo, Ye ^b   Guo, Zhaopei ^a   Zhu, Xiaojuan ^b   Chen, Xuesi ^a  

^a CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY   (China)

^b NORTHEAST NORMAL UNIVERSITY   (China)

^c UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

Blood brain barrier; Noninvasive glioma gene therapy; Polyethylenimine; Polylysine; Suicide gene

Indexed keywords

AMINO ACIDS; BIODEGRADABILITY; BLOOD; CELL DEATH; DYES; GENE TRANSFER; GENES; MEDICAL NANOTECHNOLOGY; MOLECULAR BIOLOGY; PHASE LOCKED LOOPS; TUMORS; VIRUSES;

BLOOD-BRAIN BARRIER; GENE DELIVERY SYSTEMS; GLIOBLASTOMA MULTIFORME; POLYETHYLENIMINES; POLYLYSINE; SYSTEMIC ADMINISTRATION; TRANSFECTION ANALYSIS; TRANSFECTION EFFICIENCY;

GENE THERAPY;

ANGIOPEP 2; CASPASE 3; CLAUDIN 1; COPOLYMER; GANCICLOVIR; JUNCTIONAL ADHESION MOLECULE; KI 67 ANTIGEN; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN; MACROGOL; POLYETHYLENEIMINE; POLYLYSINE; PROTEIN ZO1; PROTEIN ZO2; THYMIDINE KINASE; UNCLASSIFIED DRUG; ANGIOPEP-2; DNA; MACROGOL DERIVATIVE; NANOPARTICLE; PEPTIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BIODEGRADABILITY; BLOOD BRAIN BARRIER; CANCER INHIBITION; CANCER SURVIVAL; CANCER THERAPY; CELL PROLIFERATION; CONTROLLED STUDY; CORPUS STRIATUM; CYTOTOXICITY; DRUG ACCUMULATION; DRUG MECHANISM; GENE VECTOR; GENETIC TRANSFECTION; GLIOMA; HERPES SIMPLEX VIRUS 1; HUMAN; HUMAN CELL; IN VIVO STUDY; MOUSE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PRIORITY JOURNAL; SUICIDE GENE THERAPY; TRANSCYTOSIS; ANIMAL; BAGG ALBINO MOUSE; BRAIN TUMOR; CHEMISTRY; GENE THERAPY; GENE TRANSFER; GENETICS; HUMAN ALPHAHERPESVIRUS 1; METABOLISM; NUDE MOUSE; PROCEDURES;

ANIMALS; APOPTOSIS; BLOOD-BRAIN BARRIER; BRAIN NEOPLASMS; DNA; GENE TRANSFER TECHNIQUES; GENETIC THERAPY; GENETIC VECTORS; GLIOMA; HERPESVIRUS 1, HUMAN; HUMANS; MICE; MICE, INBRED BALB C; MICE, NUDE; NANOPARTICLES; PEPTIDES; POLYETHYLENE GLYCOLS; POLYETHYLENEIMINE; POLYLYSINE; THYMIDINE KINASE; TRANSFECTION;

EID: 84994877262     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2016.10.027     Document Type: Article

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