Polylysine-modified polyethylenimine inducing tumor apoptosis as an efficient gene carrier

Journal of Controlled Release

Volumn 172, Issue 2, 2013, Pages 410-418

  Tian, Huayu ^a   Lin, Lin ^a   Jiao, Zixue ^a   Guo, Zhaopei ^a   Chen, Jie ^a   Gao, Shiqian ^b   Zhu, Xiaojuan ^b   Chen, Xuesi ^a  

^a CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY   (China)

^b NORTHEAST NORMAL UNIVERSITY   (China)

Author keywords

Apoptosis; Gene delivery; Polyethylenimine; Polylysine; Tumor inhibition

Indexed keywords

GENE DELIVERY; HYPERBRANCHED COPOLYMERS; POLY(ADP RIBOSE) POLYMERASE 1; POLYETHYLENIMINES; POLYLYSINE; POLYMERIC GENE CARRIERS; TRANSFECTION EFFICIENCY; TUMOR INHIBITION;

AMINO ACIDS; BIOCOMPATIBILITY; BIODEGRADABLE POLYMERS; BIODEGRADATION; CELL DEATH; CYTOTOXICITY; EFFICIENCY; MOLECULAR BIOLOGY; TUMORS;

GENE TRANSFER;

CASPASE 3; DRUG CARRIER; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; PLASMID DNA; POLYETHYLENEIMINE; POLYLYSINE;

ANIMAL EXPERIMENT; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER GENE THERAPY; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; CYTOTOXICITY; ENDOCYTOSIS; FEMALE; GENE DELIVERY SYSTEM; HELA CELL; HEMOLYSIS; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MOUSE; NICK END LABELING; NONHUMAN; PARTICLE SIZE; POLYMERIZATION; PRIORITY JOURNAL; TUMOR XENOGRAFT; WESTERN BLOTTING; ZETA POTENTIAL;

APOPTOSIS; GENE DELIVERY; POLYETHYLENIMINE; POLYLYSINE; TUMOR INHIBITION;

ANIMALS; APOPTOSIS; CASPASE 3; DNA; FEMALE; GENETIC THERAPY; HELA CELLS; HUMANS; MICE; MICE, INBRED BALB C; MICE, NUDE; NEOPLASMS; PARTICLE SIZE; PLASMIDS; POLYETHYLENEIMINE; POLYLYSINE; TRANSFECTION;

EID: 84887102551     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2013.06.026     Document Type: Article

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