Dual T cell- and B cell-intrinsic deficiency in humans with biallelic RLT PR mutations

Journal of Experimental Medicine

Volumn 213, Issue 11, 2016, Pages 2413-2435

  Wang, Yi ^a,b   Ma, Cindy S ^c,d   Ling, Yun ^a,b   Bousfiha, Aziz ^e   Camcioglu, Yildiz ^f   Jacquot, Serge ^g,h   Payne, Kathryn ^c   Crestani, Elena ⁱ   Roncagalli, Romain ^k   Belkadi, Aziz ^a,b   Kerner, Gaspard ^a,b   Lorenzo, Lazaro ^a,b   Deswarte, Caroline ^a,b   Chrabieh, Maya ^a,b   Patin, Etienne ^l,m   Vincent, Quentin B ^a,b   Müller Fleckenstein, Ingrid ⁿ   Fleckenstein, Bernhard ⁿ   Ailal, Fatima ^e   Quintana Murci, Lluis ^l,m   Fraitag, Sylvie ^b   Alyanakian, Marie Alexandra ^b   Leruez Ville, Marianne ^b   Picard, Capucine ^a,b,o   Puel, Anne ^a,b   Bustamante, Jacinta ^a,b,o   Boisson Dupuis, Stéphanie ^a,b,p   Malissen, Marie ^k   Malissen, Bernard ^k   Abel, Laurent ^a,b   Hovnanian, Alain ^a,b   Notarangelo, Luigi D ^i,j   Jouanguy, Emmanuelle ^a,b,p   Tangye, Stuart G ^c,d   Béziat, Vivien ^a,b   Casanova, Jean Laurent ^a,b,o,p   more..

^a IMAGINE INSTITUTE   (France)

^b UNIVERSITÉ PARIS DESCARTES   (France)

^c GARVAN INSTITUTE OF MEDICAL RESEARCH   (Australia)

^d UNIVERSITY OF NEW SOUTH WALES   (Australia)

^e HASSAN II UNIVERSITY   (Morocco)

^f ISTANBUL UNIVERSITY   (Turkey)

^g ROUEN UNIVERSITY HOSPITAL   (France)

^h UNIVERSITY OF ROUEN   (France)

ⁱ BOSTON CHILDREN S HOSPITAL   (United States)

^j HARVARD STEM CELL INSTITUTE   (United States)

^k CENTRE D IMMUNOLOGIE DE MARSEILLE LUMINY   (France)

^l INSTITUT PASTEUR   (France)

^m CNRS   (France)

ⁿ UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^o HÔPITAL NECKER ENFANTS MALADES   (France)

^p ROCKEFELLER UNIVERSITY   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

B LYMPHOCYTE RECEPTOR; CD28 ANTIGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; ACTIN BINDING PROTEIN; LRRC16A PROTEIN, HUMAN; LYMPHOCYTE ANTIGEN RECEPTOR;

ADULT; ALLELE; ARTICLE; B LYMPHOCYTE; CD4+ T LYMPHOCYTE; CLINICAL ARTICLE; COMBINED IMMUNODEFICIENCY; CONTROLLED STUDY; DIMERIZATION; EX VIVO STUDY; FEMALE; GENE OVEREXPRESSION; HELPER CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNE RESPONSE; IN VITRO STUDY; LOSS OF FUNCTION MUTATION; MALE; MEMORY CELL; MEMORY T LYMPHOCYTE; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; RLTPR GENE; SIGNAL TRANSDUCTION; T LYMPHOCYTE; TH1 CELL; TH17 CELL; TH2 CELL; YOUNG ADULT; ADOLESCENT; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SURVIVAL; CHILD; GENETICS; HEK293 CELL LINE; IMMUNOLOGICAL MEMORY; IMMUNOLOGY; IMMUNOPHENOTYPING; LEUKOCYTE; METABOLISM; MUTATION; NUCLEOTIDE SEQUENCE; PATHOLOGY; PEDIGREE; PHENOTYPE; PRESCHOOL CHILD;

ADOLESCENT; ADULT; ALLELES; ANTIGENS, CD28; B-LYMPHOCYTES; BASE SEQUENCE; CD4-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SURVIVAL; CHILD; CHILD, PRESCHOOL; DIMERIZATION; FEMALE; HEK293 CELLS; HUMANS; IMMUNOLOGIC MEMORY; IMMUNOPHENOTYPING; LEUKOCYTES; MALE; MICROFILAMENT PROTEINS; MUTATION; NF-KAPPA B; PEDIGREE; PHENOTYPE; RECEPTORS, ANTIGEN, B-CELL; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; TH17 CELLS; TH2 CELLS; YOUNG ADULT;

EID: 84994667641     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20160576     Document Type: Article

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