메뉴 건너뛰기




Volumn 123, Issue 2, 2013, Pages 580-593

An obligate cell-intrinsic function for CD28 in Tregs

Author keywords

[No Author keywords available]

Indexed keywords

CD28 ANTIGEN; CHEMOKINE RECEPTOR CCR6; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; PROGRAMMED DEATH 1 RECEPTOR; TRANSCRIPTION FACTOR FOXP3;

EID: 84873337168     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI65013     Document Type: Article
Times cited : (177)

References (39)
  • 1
    • 0037385314 scopus 로고    scopus 로고
    • An essential role for Scurfin in CD4 (+) CD25 (+) T regulatory cells
    • Khattri R, Cox T, Yasayko SA, Ramsdell F. An essential role for Scurfin in CD4 (+) CD25 (+) T regulatory cells. Nat Immunol. 2003;4(4):337-342.
    • (2003) Nat Immunol. , vol.4 , Issue.4 , pp. 337-342
    • Khattri, R.1    Cox, T.2    Yasayko, S.A.3    Ramsdell, F.4
  • 2
    • 0037385330 scopus 로고    scopus 로고
    • Foxp3 programs the development and function of CD4 (+) CD25 (+) regulatory T cells
    • Fontenot JD, Gavin MA, Rudensky AY. Foxp3 programs the development and function of CD4 (+) CD25 (+) regulatory T cells. Nat Immunol. 2003;4(4):330-336.
    • (2003) Nat Immunol. , vol.4 , Issue.4 , pp. 330-336
    • Fontenot, J.D.1    Gavin, M.A.2    Rudensky, A.Y.3
  • 3
    • 0347785480 scopus 로고    scopus 로고
    • Control of regulatory T cell development by the transcription factor Foxp3
    • Hori S, Nomura T, Sakaguchi S. Control of regulatory T cell development by the transcription factor Foxp3. Science. 2003;299(5609):1057-1061.
    • (2003) Science , vol.299 , Issue.5609 , pp. 1057-1061
    • Hori, S.1    Nomura, T.2    Sakaguchi, S.3
  • 4
    • 0036346861 scopus 로고    scopus 로고
    • Clinical and molecular features of the immunodysregulation, polyendocrinopathy, enteropathy, X linked (IPEX) syndrome
    • Wildin RS, Smyk-Pearson S, Filipovich AH. Clinical and molecular features of the immunodysregulation, polyendocrinopathy, enteropathy, X linked (IPEX) syndrome. J Med Genet. 2002;39(8):537-545.
    • (2002) J Med Genet. , vol.39 , Issue.8 , pp. 537-545
    • Wildin, R.S.1    Smyk-Pearson, S.2    Filipovich, A.H.3
  • 5
    • 0026178213 scopus 로고
    • X-linked lymphoreticular disease in the scurfy (sf) mutant mouse
    • Godfrey VL, Wilkinson JE, Russell LB. X-linked lymphoreticular disease in the scurfy (sf) mutant mouse. Am J Pathol. 1991;138(6):1379-1387.
    • (1991) Am J Pathol. , vol.138 , Issue.6 , pp. 1379-1387
    • Godfrey, V.L.1    Wilkinson, J.E.2    Russell, L.B.3
  • 6
    • 33846485153 scopus 로고    scopus 로고
    • Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice
    • Kim JM, Rasmussen JP, Rudensky AY. Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice. Nat Immunol. 2007;8(2):191-197.
    • (2007) Nat Immunol. , vol.8 , Issue.2 , pp. 191-197
    • Kim, J.M.1    Rasmussen, J.P.2    Rudensky, A.Y.3
  • 8
    • 79954459308 scopus 로고    scopus 로고
    • Intrinsic and extrinsic control of peripheral T-cell tolerance by costimulatory molecules of the CD28/B7 family
    • Bour-Jordan H, Esensten JH, Martinez-Llordella M, Penaranda C, Stumpf M, Bluestone JA. Intrinsic and extrinsic control of peripheral T-cell tolerance by costimulatory molecules of the CD28/B7 family. Immunol Rev. 2011;241(1):180-205.
    • (2011) Immunol Rev. , vol.241 , Issue.1 , pp. 180-205
    • Bour-Jordan, H.1    Esensten, J.H.2    Martinez-Llordella, M.3    Penaranda, C.4    Stumpf, M.5    Bluestone, J.A.6
  • 9
    • 0345476290 scopus 로고    scopus 로고
    • Requirement for T-cell apoptosis in the induction of peripheral transplantation tolerance
    • Wells AD, et al. Requirement for T-cell apoptosis in the induction of peripheral transplantation tolerance. Nat Med. 1999;5(11):1303-1307.
    • (1999) Nat Med. , vol.5 , Issue.11 , pp. 1303-1307
    • Wells, A.D.1
  • 10
    • 0001624906 scopus 로고    scopus 로고
    • T cell death and transplantation tolerance
    • Li XC, Strom TB, Turka LA, Wells AD. T cell death and transplantation tolerance. Immunity. 2001;14(4):407-416.
    • (2001) Immunity , vol.14 , Issue.4 , pp. 407-416
    • Li, X.C.1    Strom, T.B.2    Turka, L.A.3    Wells, A.D.4
  • 11
    • 0033682056 scopus 로고    scopus 로고
    • B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes
    • Salomon B, et al. B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes. Immunity. 2000;12(4):431-440.
    • (2000) Immunity , vol.12 , Issue.4 , pp. 431-440
    • Salomon, B.1
  • 12
    • 0141920662 scopus 로고    scopus 로고
    • Cutting edge: CD28 controls peripheral homeostasis of CD4 (+) CD25 (+) regulatory T cells
    • Tang Q, et al. Cutting edge: CD28 controls peripheral homeostasis of CD4 (+) CD25 (+) regulatory T cells. J Immunol. 2003;171(7):3348-3352.
    • (2003) J Immunol. , vol.171 , Issue.7 , pp. 3348-3352
    • Tang, Q.1
  • 13
    • 84862784932 scopus 로고    scopus 로고
    • Deleterious effect of CTLA4-Ig on a Treg-dependent transplant model
    • Riella LV, et al. Deleterious effect of CTLA4-Ig on a Treg-dependent transplant model. Am J Transplant. 2012;12(4):846-855.
    • (2012) Am J Transplant , vol.12 , Issue.4 , pp. 846-855
    • Riella, L.V.1
  • 14
    • 16044371193 scopus 로고    scopus 로고
    • CD28/B7 regulation of Th1 and Th2 subsets in the development of autoimmune diabetes
    • Lenschow DJ, et al. CD28/B7 regulation of Th1 and Th2 subsets in the development of autoimmune diabetes. Immunity. 1996;5(3):285-293.
    • (1996) Immunity , vol.5 , Issue.3 , pp. 285-293
    • Lenschow, D.J.1
  • 15
    • 13944260538 scopus 로고    scopus 로고
    • CD28 costimulation of developing thymocytes induces Foxp3 expression and regulatory T cell differentiation independently of interleukin 2
    • Tai X, Cowan M, Feigenbaum L, Singer A. CD28 costimulation of developing thymocytes induces Foxp3 expression and regulatory T cell differentiation independently of interleukin 2. Nat Immunol. 2005;6(2):152-162.
    • (2005) Nat Immunol. , vol.6 , Issue.2 , pp. 152-162
    • Tai, X.1    Cowan, M.2    Feigenbaum, L.3    Singer, A.4
  • 16
    • 53749094183 scopus 로고    scopus 로고
    • CTLA-4 control over Foxp3+ regulatory T cell function
    • Wing K, et al. CTLA-4 control over Foxp3+ regulatory T cell function. Science. 2008;322(5899):271-275.
    • (2008) Science , vol.322 , Issue.5899 , pp. 271-275
    • Wing, K.1
  • 17
    • 63049090504 scopus 로고    scopus 로고
    • CD4+ regulatory T cells require CTLA-4 for the maintenance of systemic tolerance
    • Friedline RH, et al. CD4+ regulatory T cells require CTLA-4 for the maintenance of systemic tolerance. J Exp Med. 2009;206(2):421-434.
    • (2009) J Exp Med. , vol.206 , Issue.2 , pp. 421-434
    • Friedline, R.H.1
  • 18
    • 84855939763 scopus 로고    scopus 로고
    • Three-year outcomes from BEN-EFIT, a randomized, active-controlled, parallelgroup study in adult kidney transplant recipients
    • Vincenti F, et al. Three-year outcomes from BEN-EFIT, a randomized, active-controlled, parallelgroup study in adult kidney transplant recipients. Am J Transplant. 2012;12(1):210-217.
    • (2012) Am J Transplant , vol.12 , Issue.1 , pp. 210-217
    • Vincenti, F.1
  • 19
    • 41549159660 scopus 로고    scopus 로고
    • Regulatory T cell-derived interleukin-10 limits inflammation at environmental interfaces
    • Rubtsov YP, et al. Regulatory T cell-derived interleukin-10 limits inflammation at environmental interfaces. Immunity. 2008;28(4):546-558.
    • (2008) Immunity , vol.28 , Issue.4 , pp. 546-558
    • Rubtsov, Y.P.1
  • 20
    • 0041884743 scopus 로고    scopus 로고
    • Continuous activation of autoreactive CD4+ CD25+ regulatory T cells in the steady state
    • Fisson S, et al. Continuous activation of autoreactive CD4+ CD25+ regulatory T cells in the steady state. J Exp Med. 2003;198(5):737-746.
    • (2003) J Exp Med. , vol.198 , Issue.5 , pp. 737-746
    • Fisson, S.1
  • 21
    • 32644459908 scopus 로고    scopus 로고
    • Antigen-specific regulatory T cells-ex vivo expansion and therapeutic potential
    • Masteller EL, Tang Q, Bluestone JA. Antigen-specific regulatory T cells-ex vivo expansion and therapeutic potential. Semin Immunol. 2006;18(2):103-110.
    • (2006) Semin Immunol. , vol.18 , Issue.2 , pp. 103-110
    • Masteller, E.L.1    Tang, Q.2    Bluestone, J.A.3
  • 22
    • 0035320679 scopus 로고    scopus 로고
    • Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide
    • Jordan MS, et al. Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide. Nat Immunol. 2001;2(4):301-306.
    • (2001) Nat Immunol. , vol.2 , Issue.4 , pp. 301-306
    • Jordan, M.S.1
  • 23
    • 0037450727 scopus 로고    scopus 로고
    • T cell regulation as a side effect of homeostasis and competition
    • Barthlott T, Kassiotis G, Stockinger B. T cell regulation as a side effect of homeostasis and competition. J Exp Med. 2003;197(4):451-460.
    • (2003) J Exp Med. , vol.197 , Issue.4 , pp. 451-460
    • Barthlott, T.1    Kassiotis, G.2    Stockinger, B.3
  • 24
    • 23844478869 scopus 로고    scopus 로고
    • Natural recovery and protection from autoimmune encephalomyelitis: Contribution of CD4+CD25+ regulatory cells within the central nervous system
    • McGeachy MJ, Stephens LA, Anderton SM. Natural recovery and protection from autoimmune encephalomyelitis: contribution of CD4+CD25+ regulatory cells within the central nervous system. J Immunol. 2005;175(5):3025-3032.
    • (2005) J Immunol. , vol.175 , Issue.5 , pp. 3025-3032
    • McGeachy, M.J.1    Stephens, L.A.2    Anderton, S.M.3
  • 25
    • 73949088551 scopus 로고    scopus 로고
    • PD-L1 regulates the development, maintenance, and function of induced regulatory T cells
    • Francisco LM, et al. PD-L1 regulates the development, maintenance, and function of induced regulatory T cells. J Exp Med. 2009;206(13):3015-3029.
    • (2009) J Exp Med. , vol.206 , Issue.13 , pp. 3015-3029
    • Francisco, L.M.1
  • 26
    • 77953747963 scopus 로고    scopus 로고
    • The PD-1 pathway in tolerance and autoimmunity
    • Francisco LM, Sage PT, Sharpe AH. The PD-1 pathway in tolerance and autoimmunity. Immunol Rev. 2010;236:219-242.
    • (2010) Immunol Rev. , vol.236 , pp. 219-242
    • Francisco, L.M.1    Sage, P.T.2    Sharpe, A.H.3
  • 27
    • 61949334905 scopus 로고    scopus 로고
    • Regulatory T cells sequentially migrate from inflamed tissues to draining lymph nodes to suppress the alloimmune response
    • Zhang N, et al. Regulatory T cells sequentially migrate from inflamed tissues to draining lymph nodes to suppress the alloimmune response. Immunity. 2009;30(3):458-469.
    • (2009) Immunity , vol.30 , Issue.3 , pp. 458-469
    • Zhang, N.1
  • 28
    • 77949747054 scopus 로고    scopus 로고
    • Activated regulatory T cells are the major T cell type emigrating from the skin during a cutaneous immune response in mice
    • Tomura M, et al. Activated regulatory T cells are the major T cell type emigrating from the skin during a cutaneous immune response in mice. J Clin Invest. 2010;120(3):883-893.
    • (2010) J Clin Invest. , vol.120 , Issue.3 , pp. 883-893
    • Tomura, M.1
  • 29
    • 84863549067 scopus 로고    scopus 로고
    • Allograft rejection is restrained by short-lived TIM-3+PD-1+Foxp3+ Tregs
    • Gupta S, et al. Allograft rejection is restrained by short-lived TIM-3+PD-1+Foxp3+ Tregs. J Clin Invest. 2012;122(7):2395-2404.
    • (2012) J Clin Invest. , vol.122 , Issue.7 , pp. 2395-2404
    • Gupta, S.1
  • 30
    • 84864820799 scopus 로고    scopus 로고
    • IL-2 receptor signaling is essential for the development of Klrg1+ terminally differentiated T regulatory cells
    • Cheng G, Yuan X, Tsai MS, Podack ER, Yu A, Malek TR. IL-2 receptor signaling is essential for the development of Klrg1+ terminally differentiated T regulatory cells. J Immunol. 2012;189(4):1780-1791.
    • (2012) J Immunol. , vol.189 , Issue.4 , pp. 1780-1791
    • Cheng, G.1    Yuan, X.2    Tsai, M.S.3    Podack, E.R.4    Yu, A.5    Malek, T.R.6
  • 31
    • 33745968543 scopus 로고    scopus 로고
    • Regulatory T-cell compartmentalization and trafficking
    • Wei S, Kryczek I, Zou W. Regulatory T-cell compartmentalization and trafficking. Blood. 2006;108(2):426-431.
    • (2006) Blood , vol.108 , Issue.2 , pp. 426-431
    • Wei, S.1    Kryczek, I.2    Zou, W.3
  • 32
    • 27144524938 scopus 로고    scopus 로고
    • Migration matters: Regulatory T-cell compartmentalization determines suppressive activity in vivo
    • Siegmund K, et al. Migration matters: regulatory T-cell compartmentalization determines suppressive activity in vivo. Blood. 2005;106(9):3097-3104.
    • (2005) Blood , vol.106 , Issue.9 , pp. 3097-3104
    • Siegmund, K.1
  • 33
    • 58849124250 scopus 로고    scopus 로고
    • CCR6 regulates the migration of inflammatory and regulatory T cells
    • Yamazaki T, et al. CCR6 regulates the migration of inflammatory and regulatory T cells. J Immunol. 2008;181(12):8391-8401.
    • (2008) J Immunol. , vol.181 , Issue.12 , pp. 8391-8401
    • Yamazaki, T.1
  • 34
    • 33644843085 scopus 로고    scopus 로고
    • Cutting Edge: CD28 Controls dominant regulatory T cell activity during active immunization
    • Lyddane C, Gajewska BU, Santos E, King PD, Furtado GC, Sadelain M. Cutting Edge: CD28 Controls dominant regulatory T cell activity during active immunization. J Immunol. 2006;176(6):3306-3310.
    • (2006) J Immunol. , vol.176 , Issue.6 , pp. 3306-3310
    • Lyddane, C.1    Gajewska, B.U.2    Santos, E.3    King, P.D.4    Furtado, G.C.5    Sadelain, M.6
  • 35
    • 53149114893 scopus 로고    scopus 로고
    • CD28 controls differentiation of regulatory T cells from naive CD4 T cells
    • Guo F, Iclozan C, Suh WK, Anasetti C, Yu XZ. CD28 controls differentiation of regulatory T cells from naive CD4 T cells. J Immunol. 2008;181(4):2285-2291.
    • (2008) J Immunol. , vol.181 , Issue.4 , pp. 2285-2291
    • Guo, F.1    Iclozan, C.2    Suh, W.K.3    Anasetti, C.4    Yu, X.Z.5
  • 36
    • 0027282960 scopus 로고
    • Characterization of CTLA-4 structure and expression on human T cells
    • Lindsten T, et al. Characterization of CTLA-4 structure and expression on human T cells. J Immunol. 1993;151(7):3489-3499.
    • (1993) J Immunol. , vol.151 , Issue.7 , pp. 3489-3499
    • Lindsten, T.1
  • 37
    • 84861451140 scopus 로고    scopus 로고
    • Loss of epigenetic modification driven by the Foxp3 transcription factor leads to regulatory T cell insufficiency
    • Bettini ML, et al. Loss of epigenetic modification driven by the Foxp3 transcription factor leads to regulatory T cell insufficiency. Immunity. 2012;36(5):717-730.
    • (2012) Immunity , vol.36 , Issue.5 , pp. 717-730
    • Bettini, M.L.1
  • 38
    • 84861424521 scopus 로고    scopus 로고
    • An N-terminal mutation of the Foxp3 transcription factor alleviates arthritis but exacerbates diabetes
    • Darce J, et al. An N-terminal mutation of the Foxp3 transcription factor alleviates arthritis but exacerbates diabetes. Immunity. 2012;36(5):731-741.
    • (2012) Immunity , vol.36 , Issue.5 , pp. 731-741
    • Darce, J.1
  • 39
    • 0026649765 scopus 로고
    • Identification and distribution of the costimulatory receptor CD28 in the mouse
    • Gross JA, Callas E, Allison JP. Identification and distribution of the costimulatory receptor CD28 in the mouse. J Immunol. 1992;149(2):380-388.
    • (1992) J Immunol. , vol.149 , Issue.2 , pp. 380-388
    • Gross, J.A.1    Callas, E.2    Allison, J.P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.