Impairment of immunity to Candida and Mycobacterium in humans with bi-allelic RORC mutations

Science

Volumn 349, Issue 6248, 2015, Pages 606-613

  Okada, Satoshi ^a,b   Markle, Janet G ^a   Deenick, Elissa K ^c,d   Mele, Federico ^e   Averbuch, Dina ^f   Lagos, Macarena ^g,h   Alzahrani, Mohammed ⁱ   Al Muhsen, Saleh ^i,j   Halwani, Rabih ^j   Ma, Cindy S ^c,d   Wong, Natalie ^c   Soudais, Claire ^k   Henderson, Lauren A ^l   Marzouqa, Hiyam ^m   Shamma, Jamal ^m   Gonzalez, Marcela ^g   Martinez Barricarte, Rubén ^a   Okada, Chizuru ^a   Avery, Danielle T ^c   Latorre, Daniela ^e   Deswarte, Caroline ^n,o   Jabot Hanin, Fabienne ^n,o   Torrado, Egidio ^p,y   Fountain, Jeffrey ^p,z   Belkadi, Aziz ^n,o   Itan, Yuval ^a   Boisson, Bertrand ^a   Migaud, Mélanie ^n,o   Lindestam Arlehamn, Cecilia S ^q   Sette, Alessandro ^q   Breton, Sylvain ^r   Cluskey, James ^s   Rossjohn, Jamie ^t,u   De Villartay, Jean Pierre ^o   Moshous, Despina ^o,r   Hambleton, Sophie ^v   Latour, Sylvain ^o   Arkwright, Peter D ^w   Picard, Capucine ^a,n,o,r   Lantz, Olivier ^k   Engelhard, Dan ^f   Kobayashi, Masao ^b   Abel, Laurent ^a,n,o   Cooper, Andrea M ^p   Notarangelo, Luigi D ^l   Boisson Dupuis, Stéphanie ^a,n,o   Puel, Anne ^a,n,o   Sallusto, Federica ^e   Bustamante, Jacinta ^a,n,o,r   Tangye, Stuart G ^c,d   Casanova, Jean Laurent ^a,n,o,r,x   more..

^a ROCKEFELLER UNIVERSITY   (United States)

^b HIROSHIMA UNIVERSITY   (Japan)

^c GARVAN INSTITUTE OF MEDICAL RESEARCH   (Australia)

^d UNIVERSITY OF NEW SOUTH WALES   (Australia)

^e INSTITUTE FOR RESEARCH IN BIOMEDICINE   (Switzerland)

^f HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

^g UNIVERSIDAD DE VALPARAÍSO   (Chile)

^h HOSPITAL PADRE HURTADO   (Chile)

ⁱ KING FAISAL SPECIALIST HOSPITAL AND RESEARCH CENTER   (Saudi Arabia)

^j KING SAUD UNIVERSITY   (Saudi Arabia)

^k PSL RESEARCH UNIVERSITY   (France)

^l BOSTON CHILDREN S HOSPITAL   (United States)

^m Caritas Baby Hospital   (Israel)

ⁿ IMAGINE INSTITUTE   (France)

^o UNIVERSITÉ PARIS DESCARTES   (France)

^p TRUDEAU INSTITUTE   (United States)

^q LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

^r HÔPITAL NECKER ENFANTS MALADES   (France)

^s UNIVERSITY OF MELBOURNE   (Australia)

^t MONASH UNIVERSITY   (Australia)

^u CARDIFF UNIVERSITY   (United Kingdom)

^v NEWCASTLE UNIVERSITY   (United Kingdom)

^w UNIVERSITY OF MANCHESTER   (United Kingdom)

^x HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^y UNIVERSITY OF MINHO   (Portugal)

^z CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CCR6; CHEMOKINE RECEPTOR CXCR3; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 12; INTERLEUKIN 12P40; INTERLEUKIN 12PR BETA1; INTERLEUKIN 17; INTERLEUKIN 17F; INTERLEUKIN 22; INTERLEUKIN 4; INTERLEUKIN 5; RETINOID RELATED ORPHAN RECEPTOR GAMMA; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG; LYMPHOCYTE ANTIGEN RECEPTOR; RORC PROTEIN, HUMAN;

ALLELE; BACTERIUM; DISEASE PREVALENCE; FUNGUS; IMMUNITY; PUBLIC HEALTH;

ARTICLE; ATYPICAL MYCOBACTERIUM; BACTERIAL IMMUNITY; BCG VACCINATION; CANDIDA; CANDIDA ALBICANS; CANDIDIASIS; CD3+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CELL DIFFERENTIATION; CERVICAL LYMPH NODE; CHILD; CLINICAL ARTICLE; CONTROLLED CLINICAL TRIAL (TOPIC); CYTOKINE PRODUCTION; DNA BINDING; DOMINANT INHERITANCE; EXOME; FRAMESHIFT MUTATION; HUMAN; IMMUNE DEFICIENCY; LOSS OF FUNCTION MUTATION; MOLECULAR WEIGHT; MUCOCUTANEOUS CANDIDIASIS; MYCOBACTERIOSIS; MYCOBACTERIUM; MYCOBACTERIUM BOVIS; NONHUMAN; NONSENSE MUTATION; PHENOTYPE; PRIORITY JOURNAL; STOP CODON; T LYMPHOCYTE; T LYMPHOCYTE SUBPOPULATION; TH17 CELL; ABNORMALITIES; ALLELE; ANIMAL; BOVINE; BOVINE TUBERCULOSIS; COMPLICATION; DNA MUTATIONAL ANALYSIS; FEMALE; GENE REARRANGEMENT; GENETICS; IMMUNITY; IMMUNOLOGY; ISOLATION AND PURIFICATION; LUNG TUBERCULOSIS; MOUSE; MUTATION; MYCOBACTERIUM TUBERCULOSIS; PEDIGREE; PRESCHOOL CHILD; SEVERE COMBINED IMMUNODEFICIENCY; THYMUS;

CANDIDA; MYCOBACTERIUM;

ALLELES; ANIMALS; CANDIDA ALBICANS; CANDIDIASIS, CHRONIC MUCOCUTANEOUS; CATTLE; CHILD; CHILD, PRESCHOOL; DNA MUTATIONAL ANALYSIS; EXOME; FEMALE; GENE REARRANGEMENT, ALPHA-CHAIN T-CELL ANTIGEN RECEPTOR; HUMANS; IMMUNITY; INTERFERON-GAMMA; INTERLEUKIN-17; MICE; MUTATION; MYCOBACTERIUM BOVIS; MYCOBACTERIUM TUBERCULOSIS; NUCLEAR RECEPTOR SUBFAMILY 1, GROUP F, MEMBER 3; PEDIGREE; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA; SEVERE COMBINED IMMUNODEFICIENCY; T-LYMPHOCYTES; THYMUS GLAND; TUBERCULOSIS, BOVINE; TUBERCULOSIS, PULMONARY;

EID: 84939154723     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aaa4282     Document Type: Article

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