Human erythrocyte PIG-A assay: An easily monitored index of gene mutation requiring low volume blood samples

Environmental and Molecular Mutagenesis

Volumn 56, Issue 4, 2015, Pages 366-377

  Dertinger, Stephen D ^a   Avlasevich, Svetlana L ^a   Bemis, Jeffrey C ^a   Chen, Yuhchyau ^b   Macgregor, James T ^c  

^a LITRON LABORATORIES   (United States)

^b UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^c Toxicology Consulting Services   (United States)

Author keywords

CD55; CD59; Flow cytometry; Mutation; Peripheral blood; PIG A gene

Indexed keywords

DECAY ACCELERATING FACTOR; GLYCAN DERIVATIVE; PHOSPHATIDYLINOSITOL; CD59 ANTIGEN; CD59 PROTEIN, HUMAN; MEMBRANE PROTEIN; PHOSPHATIDYLINOSITOL GLYCAN-CLASS A PROTEIN;

ADULT; AGED; ANIMAL EXPERIMENT; ANTIBODY LABELING; ARTICLE; BLOOD SAMPLING; CELL MUTANT; CELL SEPARATION; CONTROLLED STUDY; DNA DAMAGE; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL FACTOR; ERYTHROCYTE; FEMALE; GENE; GENE MUTATION; HUMAN; HUMAN CELL; HUMAN ERYTHROCYTE PIG-A ASSAY; IMMUNOMAGNETIC SEPARATION; MAJOR CLINICAL STUDY; MALE; MEASUREMENT ACCURACY; MIDDLE AGED; NONHUMAN; PHENOTYPE; PHOSPHATIDYLINOSITOL GLYCAN CLASS A GENE; QUALITY CONTROL; RAT; RETICULOCYTE; SPONTANEOUS MUTATION; WILD TYPE; AGE; FLOW CYTOMETRY; GENETICS; MUTATION; MUTATION RATE; PHYSIOLOGY; PROCEDURES; REPRODUCIBILITY;

RODENTIA; SUIDAE;

ADULT; AGE FACTORS; AGED; ANTIGENS, CD55; ANTIGENS, CD59; BLOOD SPECIMEN COLLECTION; ERYTHROCYTES; FEMALE; FLOW CYTOMETRY; HUMANS; IMMUNOMAGNETIC SEPARATION; MALE; MEMBRANE PROTEINS; MIDDLE AGED; MUTATION; MUTATION RATE; REPRODUCIBILITY OF RESULTS; RETICULOCYTES;

EID: 84928005033     PISSN: 08936692     EISSN: 10982280     Source Type: Journal    
DOI: 10.1002/em.21924     Document Type: Article

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