Miniaturized flow cytometry-based CHO-K1 micronucleus assay discriminates aneugenic and clastogenic modes of action

Environmental and Molecular Mutagenesis

Volumn 52, Issue 4, 2011, Pages 280-286

  Bryce, Steven M ^a   Avlasevich, Svetlana L ^a   Bemis, Jeffrey C ^a   Dertinger, Stephen D ^a  

^a LITRON LABORATORIES   (United States)

Author keywords

Aneugen; Flow cytometry; Genotoxicity; Micronuclei; Mode of action

Indexed keywords

4 NITROQUINOLINE 1 OXIDE; AMPICILLIN; ANEUGEN; ANTHRANILIC ACID; BLEOMYCIN SULFATE; CADMIUM CHLORIDE; CARBENDAZIM; CLASTOGEN; COLCHICINE; CYCLOHEXANONE; DEMECOLCINE; DIMETHYL SULFOXIDE; ESTRADIOL; ETHIONAMIDE; ETHYLENE GLYCOL; MESYLIC ACID ETHYL ESTER; MESYLIC ACID METHYL ESTER; METHYLNITRONITROSOGUANIDINE; MITOMYCIN C; NALIDIXIC ACID; NOCODAZOLE; PACLITAXEL; PHENANTHRENE; PYRENE; PYRIDINE; SODIUM CHLORIDE; SULFAFURAZOLE; VINBLASTINE SULFATE; VINCRISTINE SULFATE;

ANIMAL CELL; ARTICLE; CHO CELL; CONTROLLED STUDY; CYTOGENETICS; DIAGNOSTIC TEST ACCURACY STUDY; FLOW CYTOMETRY; FLUORESCENCE; GENOTOXICITY; IN VITRO STUDY; MICRONUCLEUS; MICRONUCLEUS TEST; NONHUMAN; SENSITIVITY AND SPECIFICITY;

ANEUGENS; ANIMALS; CHO CELLS; CRICETINAE; CRICETULUS; FLOW CYTOMETRY; MICRONUCLEUS TESTS; MINIATURIZATION; MUTAGENS;

CRICETULUS GRISEUS;

EID: 78650658372     PISSN: 08936692     EISSN: 10982280     Source Type: Journal    
DOI: 10.1002/em.20618     Document Type: Article

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