Metabolic flexibility of mitochondrial respiratory chain disorders predicted by computer modelling

Mitochondrion

Volumn 31, Issue , 2016, Pages 45-55

  Zieliński, Łukasz P ^a,b   Smith, Anthony C ^a   Smith, Alexander G ^a   Robinson, Alan J ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Electron transport chain; Flux balance analysis; Metabolism; Mitochondrial disease

Indexed keywords

ADENOSINE TRIPHOSPHATE; CYTOCHROME C OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SUCCINATE DEHYDROGENASE (UBIQUINONE); UBIQUINOL CYTOCHROME C REDUCTASE;

ARTICLE; CARDIAC MUSCLE CELL; CITRIC ACID CYCLE; COMPLEX I DEFICIENCY; COMPLEX II DEFICIENCY; COMPLEX III DEFICIENCY; COMPUTER MODEL; COMPUTER SIMULATION; CONTROLLED STUDY; CYTOCHROME C OXIDASE DEFICIENCY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; HUMAN; HUMAN CELL; METABOLIC FLEXIBILITY; METABOLIC PARAMETERS; MITOCHONDRIAL RESPIRATION; MITOCHONDRIAL RESPIRATORY CHAIN DISORDER; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; DEFICIENCY; METABOLISM; MITOCHONDRION;

ADENOSINE TRIPHOSPHATE; COMPUTER SIMULATION; CYTOCHROME-C OXIDASE DEFICIENCY; ELECTRON TRANSPORT COMPLEX I; ELECTRON TRANSPORT COMPLEX II; ELECTRON TRANSPORT COMPLEX III; HUMANS; MITOCHONDRIA; MYOCYTES, CARDIAC;

EID: 84994442721     PISSN: 15677249     EISSN: 18728278     Source Type: Journal    
DOI: 10.1016/j.mito.2016.09.003     Document Type: Article

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