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Volumn 90, Issue 2, 2011, Pages 220-223

Branched-chain amino acid metabolism in heart disease: An epiphenomenon or a real culprit?

Author keywords

Branched chain amino acid; Heart failure; PP2Cm

Indexed keywords

BRANCHED CHAIN AMINO ACID; BRANCHED CHAIN KETO ACID; ISOLEUCINE; LEUCINE; MAMMALIAN TARGET OF RAPAMYCIN; PHOSPHOPROTEIN PHOSPHATASE 2; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; VALINE;

EID: 79955456000     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvr070     Document Type: Article
Times cited : (163)

References (40)
  • 1
    • 0001463166 scopus 로고
    • Metabolic studies on the human heart in vivo. I. Studies on carbohydrate metabolism ofthe human heart
    • Bing RJ, Siegel A, Vitale A, Balboni F, Sparks E, Taeschler M et al. Metabolic studies on the human heart in vivo. I. Studies on carbohydrate metabolism ofthe human heart. Am J Med 1953;15:284-296.
    • (1953) Am J Med , vol.15 , pp. 284-296
    • Bing, R.J.1    Siegel, A.2    Vitale, A.3    Balboni, F.4    Sparks, E.5    Taeschler, M.6
  • 2
    • 59449085388 scopus 로고    scopus 로고
    • Energy metabolism in heart failure and remodelling
    • Ingwall JS. Energy metabolism in heart failure and remodelling. Cardiovasc Res 2009;81: 412-419.
    • (2009) Cardiovasc Res , vol.81 , pp. 412-419
    • Ingwall, J.S.1
  • 3
    • 67249122174 scopus 로고    scopus 로고
    • Metabolic modulation and cellular therapy of cardiac dysfunc-tion and failure
    • Revenco D, Morgan JP. Metabolic modulation and cellular therapy of cardiac dysfunc-tion and failure. J Cell Mol Med 2009;13:811-825.
    • (2009) J Cell Mol Med , vol.13 , pp. 811-825
    • Revenco, D.1    Morgan, J.P.2
  • 8
    • 0026097836 scopus 로고
    • Comparison of the effects of various amino acids on glycogen syn thesis lipogenesis and ketogenesis in isolated rat hepatocytes
    • Baquet A, Lavoinne A, Hue L Comparison of the effects of various amino acids on glycogen synthesis, lipogenesis and ketogenesis in isolated rat hepatocytes. Biochem J 1991;273(Pt 1):57-62.
    • (1991) Biochem J , vol.273 , Issue.PART 1 , pp. 57-62
    • Baquet, A.1    Lavoinne, A.2    Hue, L.3
  • 9
    • 0037291723 scopus 로고    scopus 로고
    • System L: Heteromeric exchangers of large, neutral amino acids involved in directional transport
    • Verrey F. System L: heteromeric exchangers of large, neutral amino acids involved in directional transport Pflugers Arch 2003;445:529-533. (Pubitemid 36286884)
    • (2003) Pflugers Archiv European Journal of Physiology , vol.445 , Issue.5 , pp. 529-533
    • Verrey, F.1
  • 10
  • 12
    • 63449111894 scopus 로고    scopus 로고
    • A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance
    • Newgard CB, An J, Bain JR, Muehlbauer MJ, Stevens RD, Lien LF et al. A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance. Cell Metab 2009;9:311-326.
    • (2009) Cell Metab , vol.9 , pp. 311-326
    • Newgard, C.B.1    An, J.2    Bain, J.R.3    Muehlbauer, M.J.4    Stevens, R.D.5    Lien, L.F.6
  • 13
    • 77957567397 scopus 로고    scopus 로고
    • Downregula-tion of AMPK accompanies leucine-and glucose-induced increases in protein synthesis and insulin resistance in rat skeletal muscle
    • Saha AK, Xu XJ, Lawson E, Deoliveira R, Brandon AE, Kraegen EW et al. Downregula-tion of AMPK accompanies leucine-and glucose-induced increases in protein syn-thesis and insulin resistance in rat skeletal muscle. Diabetes 2010;59:2426-2434.
    • (2010) Diabetes , vol.59 , pp. 2426-2434
    • Saha, A.K.1    Xu, X.J.2    Lawson, E.3    Deoliveira, R.4    Brandon, A.E.5    Kraegen, E.W.6
  • 14
    • 31344482641 scopus 로고    scopus 로고
    • Metabolism of branched-chain amino acids in maple syrup urine disease
    • Schadewaldt P, Wendel U. Metabolism of branched-chain amino acids in maple syrup urine disease. Eur J Pediatr 1997;156(Suppl. 1):S62-S66.
    • (1997) Eur J Pediatr , vol.156 , Issue.SUPPL. 1
    • Schadewaldt, P.1    Wendel, U.2
  • 16
    • 70149095362 scopus 로고    scopus 로고
    • Mul-tiple OXPHOS deficiency in the liver, kidney, heart, and skeletal muscle of patients with methylmalonic aciduria and propionic aciduria
    • de Keyzer Y, Valayannopoulos V, Benoist JF, Batteux F, Lacaille F, Hubert L et al. Mul-tiple OXPHOS deficiency in the liver, kidney, heart, and skeletal muscle of patients with methylmalonic aciduria and propionic aciduria. Pediatr Res 2009;66:91-95.
    • (2009) Pediatr Res , vol.66 , pp. 91-95
    • De Keyzer, Y.1    Valayannopoulos, V.2    Benoist, J.F.3    Batteux, F.4    Lacaille, F.5    Hubert, L.6
  • 17
    • 61449182656 scopus 로고    scopus 로고
    • Fetal dilated cardiomyopathy: An unsuspected pres-entation of methylmalonic aciduria and hyperhomocystinuria, cblC type
    • De Bie I, Nizard SD, Mitchell GA. Fetal dilated cardiomyopathy: an unsuspected pres-entation of methylmalonic aciduria and hyperhomocystinuria, cblC type. Prenat Diagn 2009;29:266-270.
    • (2009) Prenat Diagn , vol.29 , pp. 266-270
    • De Bie, I.1    Nizard, S.D.2    Mitchell, G.A.3
  • 18
    • 33644614705 scopus 로고    scopus 로고
    • 3-Methylglutaconic aciduria disorders: The clinical spectrum increases
    • Arn P, Funanage VL 3-Methylglutaconic aciduria disorders: the clinical spectrum increases. J Pediatr Hematol Oncol 2006;28:62-63.
    • (2006) J Pediatr Hematol Oncol , vol.28 , pp. 62-63
    • Arn, P.1    Funanage, V.L.2
  • 21
    • 0345735297 scopus 로고    scopus 로고
    • Mechanisms responsible for regulation of branched-chain amino acid catabolism
    • DOI 10.1016/j.bbrc.2003.11.007
    • Harris RA, Joshi M, Jeoung NH. Mechanisms responsible for regulation of branched-chain amino acid catabolism. Biochem Biophys Res Commun 2004;313:391-396. (Pubitemid 37543598)
    • (2004) Biochemical and Biophysical Research Communications , vol.313 , Issue.2 , pp. 391-396
    • Harris, R.A.1    Joshi, M.2    Jeoung, N.H.3
  • 22
    • 34147129534 scopus 로고    scopus 로고
    • A novel mitochondrial matrix serine/threonine protein phosphatase regulates the mitochondria permeability transition pore and is essential for cellular survival and development
    • DOI 10.1101/gad.1499107
    • Lu G, Ren S, Korge P, Choi J, Dong Y, Weiss J et al. A novel mitochondrial matrixserine/threonine protein phosphatase regulatesthe mitochondria permeabilitytransition pore and is essential for cellular survival and development. Genes Dev 2007;21:784-796. (Pubitemid 46572358)
    • (2007) Genes and Development , vol.21 , Issue.7 , pp. 784-796
    • Lu, G.1    Ren, S.2    Korge, P.3    Choi, J.4    Dong, Y.5    Weiss, J.6    Koehler, C.7    Chen, J.-N.8    Wang, Y.9
  • 23
    • 67651005823 scopus 로고    scopus 로고
    • Protein phosphatase 2Cm is a critical regulator of branched-chain amino acid catabolism in mice and cultured cells
    • Lu G, Sun H, She P, Youn JY, Warburton S, Ping P et al. Protein phosphatase 2Cm is a critical regulator of branched-chain amino acid catabolism in mice and cultured cells. J Clin Invest 2009;119:1678-1687.
    • (2009) J Clin Invest , vol.119 , pp. 1678-1687
    • Lu, G.1    Sun, H.2    She, P.3    Youn, J.Y.4    Warburton, S.5    Ping, P.6
  • 24
    • 0036440779 scopus 로고    scopus 로고
    • Regulation of mammalian translation factors by nutrients
    • DOI 10.1046/j.1432-1033.2002.03292.x
    • Proud CG. Regulation of mammalian translation factors by nutrients. Eur J Biochem 2002;269:5338-5349. (Pubitemid 35365523)
    • (2002) European Journal of Biochemistry , vol.269 , Issue.22 , pp. 5338-5349
    • Proud, C.G.1
  • 25
    • 0035145602 scopus 로고    scopus 로고
    • Metabolic regulation by leucine of translation initiation through the mTOR-signaling pathway by pancreatic β-cells
    • Xu G, Kwon G, Cruz WS, Marshall CA, McDaniel ML. Metabolic regulation by leucine oftranslation initiation through the mTOR-signaling pathway by pancreatic beta-cells. Diabetes 2001;50:353-360. (Pubitemid 32127292)
    • (2001) Diabetes , vol.50 , Issue.2 , pp. 353-360
    • Xu, G.1    Kwon, G.2    Cruz, W.S.3    Marshall, C.A.4    McDaniel, M.L.5
  • 26
    • 77955290360 scopus 로고    scopus 로고
    • MTORC1 regu-lates cardiac function and myocyte survival through 4E-BP1 inhibition in mice
    • Zhang D, Contu R, Latronico MV, Zhang J, Rizzi R, Catalucci D et al. MTORC1 regu-lates cardiac function and myocyte survival through 4E-BP1 inhibition in mice. J Clin Invest 2010;120:2805-2816.
    • (2010) J Clin Invest , vol.120 , pp. 2805-2816
    • Zhang, D.1    Contu, R.2    Latronico, M.V.3    Zhang, J.4    Rizzi, R.5    Catalucci, D.6
  • 27
    • 78649845396 scopus 로고    scopus 로고
    • Impaired overload-induced hypertrophy is associated with diminished mTOR signaling in insulin-resistant skeletal muscle of the obese Zucker rat
    • Katta A, Kundla S, Kakarla SK, Wu M, Fannin J, Paturi S et al. Impaired overload-induced hypertrophy is associated with diminished mTOR signaling in insulin-resistant skeletal muscle of the obese Zucker rat Am J Physiol Regul Integr Comp Physiol 2010;299:R1666-R1675.
    • (2010) Am J Physiol Regul Integr Comp Physiol , vol.299
    • Katta, A.1    Kundla, S.2    Kakarla, S.K.3    Wu, M.4    Fannin, J.5    Paturi, S.6
  • 28
    • 79953762724 scopus 로고    scopus 로고
    • Autophagy in cardiac plasticity and disease
    • Hill JA. Autophagy in cardiac plasticity and disease. Pediatr Cardiol 2011;32:282-289.
    • (2011) Pediatr Cardiol , vol.32 , pp. 282-289
    • Hill, J.A.1
  • 29
    • 79955370426 scopus 로고    scopus 로고
    • Regulation of autophagy in the heart: 'You only Live Twice'
    • doi:10.1089/ars.2010.3479. Published online ahead of print 7 January 2011
    • Aviv Y, Shaw J, Gang H, Kirshenbaum LA. Regulation of autophagy in the heart: 'You Only Live Twice'. Antioxid Redox Signal 2011; doi:10.1089/ars.2010. 3479. Published online ahead of print 7 January 2011.
    • (2011) Antioxid Redox Signal
    • Aviv, Y.1    Shaw, J.2    Gang, H.3    Kirshenbaum, L.A.4
  • 30
    • 79953736356 scopus 로고    scopus 로고
    • Is Autophagy in response to ischemia and reperfusion protective or detrimental for the heart?
    • Sciarretta S, Hariharan N, Monden Y, Zablocki D, Sadoshima J. Is Autophagy in response to ischemia and reperfusion protective or detrimental for the heart? Pediatr Cardiol 2010;32:275-281.
    • (2010) Pediatr Cardiol , vol.32 , pp. 275-281
    • Sciarretta, S.1    Hariharan, N.2    Monden, Y.3    Zablocki, D.4    Sadoshima, J.5
  • 31
  • 33
    • 59849110194 scopus 로고    scopus 로고
    • Autophagy in ischemic heart disease
    • Gustafsson AB, Gottlieb RA. Autophagy in ischemic heart disease. Circ Res 2009;104: 150-158.
    • (2009) Circ Res , vol.104 , pp. 150-158
    • Gustafsson, A.B.1    Gottlieb, R.A.2
  • 35
    • 33646559999 scopus 로고    scopus 로고
    • Role of amino acids in insulin signaling in adipocytes and their potential to decrease insulin resistance of adipose tissue
    • DOI 10.1016/j.jnutbio.2006.02.008, PII S0955286306000520
    • Hinault C, Van Obberghen E, Mothe-Satney I. Role of amino acids in insulin signaling in adipocytes and their potentialto decrease insulin resistance of adipose tissue. J Nutr Biochem 2006;17:374-378. (Pubitemid 43729348)
    • (2006) Journal of Nutritional Biochemistry , vol.17 , Issue.6 , pp. 374-378
    • Hinault, C.1    Van Obberghen, E.2    Mothe-Satney, I.3
  • 36
    • 79952374033 scopus 로고    scopus 로고
    • Leucine deprivation increases hepatic insulin sensitivity via GCN2/mTOR/S6K1 and AMPK pathways
    • Xiao F, Huang Z, Li H, Yu J, Wang C, Chen S et al. Leucine deprivation increases hepatic insulin sensitivity via GCN2/mTOR/S6K1 and AMPK pathways. Diabetes 2011;60:746-756.
    • (2011) Diabetes , vol.60 , pp. 746-756
    • Xiao, F.1    Huang, Z.2    Li, H.3    Yu, J.4    Wang, C.5    Chen, S.6
  • 37
    • 77249137784 scopus 로고    scopus 로고
    • Isoleucine prevents the accumulation of tissue triglycerides and upregulates the expression of PPARalpha and uncoupling protein in diet-induced obese mice
    • Nishimura J, Masaki T, Arakawa M, Seike M, Yoshimatsu H. Isoleucine prevents the accumulation of tissue triglycerides and upregulates the expression of PPARalpha and uncoupling protein in diet-induced obese mice. J Nutr 2010;140:496-500.
    • (2010) J Nutr , vol.140 , pp. 496-500
    • Nishimura, J.1    Masaki, T.2    Arakawa, M.3    Seike, M.4    Yoshimatsu, H.5
  • 38
    • 77957661352 scopus 로고    scopus 로고
    • Branched-chain amino acid supplementation promotes survival and supports cardiac and skeletal muscle mitochondrial biogenesis in middle-aged mice
    • D'Antona G, Ragni M, Cardile A, Tedesco L, Dossena M, Bruttini F et al. Branched-chain amino acid supplementation promotes survival and supports cardiac and skeletal muscle mitochondrial biogenesis in middle-aged mice. Cell Metab 2010;12:362-372.
    • (2010) Cell Metab , vol.12 , pp. 362-372
    • D'Antona, G.1    Ragni, M.2    Cardile, A.3    Tedesco, L.4    Dossena, M.5    Bruttini, F.6
  • 39
    • 77953667219 scopus 로고    scopus 로고
    • Associ-ation of a peripheral blood metabolic profile with coronary artery disease and risk of subsequent cardiovascular events
    • Shah SH, Bain JR, Muehlbauer MJ, Stevens RD, Crosslin DR, Haynes C et al. Associ-ation of a peripheral blood metabolic profile with coronary artery disease and risk of subsequent cardiovascular events. Circ Cardiovasc Genet 2010;3:207-214.
    • (2010) Circ Cardiovasc Genet , vol.3 , pp. 207-214
    • Shah, S.H.1    Bain, J.R.2    Muehlbauer, M.J.3    Stevens, R.D.4    Crosslin, D.R.5    Haynes, C.6
  • 40
    • 64449083415 scopus 로고    scopus 로고
    • Animal models of maple syrup urine disease
    • Skvorak KJ. Animal models of maple syrup urine disease. J Inherit Metab Dis 2009;32: 229-246.
    • (2009) J Inherit Metab Dis , vol.32 , pp. 229-246
    • Skvorak, K.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.