Fumarate is cardioprotective via activation of the Nrf2 antioxidant pathway

Cell Metabolism

Volumn 15, Issue 3, 2012, Pages 361-371

  Ashrafian, Houman ^a   Czibik, Gabor ^a   Bellahcene, Mohamed ^a   Aksentijević, Dunja ^a   Smith, Anthony C ^b   Mitchell, Sarah J ^c,d   Dodd, Michael S ^a   Kirwan, Jennifer ^e   Byrne, Jonathan J ^e   Ludwig, Christian ^e   Isackson, Henrik ^a   Yavari, Arash ^a   Støttrup, Nicolaj B ^f   Contractor, Hussain ^a   Cahill, Thomas J ^a   Sahgal, Natasha ^h   Ball, Daniel R ^a   Birkler, Rune I D ^f   Hargreaves, Iain ^g   Tennant, Daniel A ^e   Land, John ^g   Lygate, Craig A ^a   Johannsen, Mogens ^f   Kharbanda, Rajesh K ^a   Neubauer, Stefan ^a   Redwood, Charles ^a   De Cabo, Rafael ^d   Ahmet, Ismayil ^d   Talan, Mark ^d   Günther, Ulrich L ^e   Robinson, Alan J ^b   Viant, Mark R ^e   Pollard, Patrick J ^g   Tyler, Damian J ^a   Watkins, Hugh ^a,h   more..

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c UNIVERSITY OF SYDNEY   (Australia)

^d NATIONAL INSTITUTE ON AGING   (United States)

^e UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^f AARHUS UNIVERSITY HOSPITAL   (Denmark)

^g NATIONAL HOSPITAL FOR NEUROLOGY AND NEUROSURGERY   (United Kingdom)

^h UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; AMINO ACID; DIMETHYLFUMARATE; FUMARATE HYDRATASE; FUMARIC ACID; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ANTIOXIDANT RESPONSIVE ELEMENT; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; GENE; GENE TARGETING; HEART INFARCTION; HEART MUSCLE ISCHEMIA; HEART PROTECTION; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN STABILITY; REPERFUSION INJURY; UPREGULATION;

ANIMALS; ANTIOXIDANTS; FUMARATE HYDRATASE; FUMARATES; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MODELS, BIOLOGICAL; MYOCARDIAL INFARCTION; NF-E2-RELATED FACTOR 2; SIGNAL TRANSDUCTION;

MUS;

EID: 84863244462     PISSN: 15504131     EISSN: 19327420     Source Type: Journal    
DOI: 10.1016/j.cmet.2012.01.017     Document Type: Article

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