-
1
-
-
0036217072
-
The lutropin/choriogonadotropin receptor, a 2002 perspective
-
11943741
-
Ascoli M Fanelli F Segaloff DL. The lutropin/choriogonadotropin receptor, a 2002 perspective. Endocr Rev (2002) 23:141–74.10.1210/edrv.23.2.046211943741
-
(2002)
Endocr Rev
, vol.23
, pp. 141-174
-
-
Ascoli, M.1
Fanelli, F.2
Segaloff, D.L.3
-
2
-
-
84888287689
-
Structural biology of glycoprotein hormones and their receptors: insights to signaling
-
24001578
-
Jiang X Dias JA He X. Structural biology of glycoprotein hormones and their receptors: insights to signaling. Mol Cell Endocrinol (2014) 382:424–51.10.1016/j.mce.2013.08.02124001578
-
(2014)
Mol Cell Endocrinol
, vol.382
, pp. 424-451
-
-
Jiang, X.1
Dias, J.A.2
He, X.3
-
3
-
-
65249116958
-
Thyrotropin and homologous glycoprotein hormone receptors: structural and functional aspects of extracellular signaling mechanisms
-
19176466
-
Kleinau G Krause G. Thyrotropin and homologous glycoprotein hormone receptors: structural and functional aspects of extracellular signaling mechanisms. Endocr Rev (2009) 30:133–51.10.1210/er.2008-004419176466
-
(2009)
Endocr Rev
, vol.30
, pp. 133-151
-
-
Kleinau, G.1
Krause, G.2
-
4
-
-
84883032068
-
Structural and functional plasticity of the luteinizing hormone/choriogonadotrophin receptor
-
23686864
-
Troppmann B Kleinau G Krause G Gromoll J. Structural and functional plasticity of the luteinizing hormone/choriogonadotrophin receptor. Hum Reprod Update (2013) 19(5):583–602.10.1093/humupd/dmt02323686864
-
(2013)
Hum Reprod Update
, vol.19
, Issue.5
, pp. 583-602
-
-
Troppmann, B.1
Kleinau, G.2
Krause, G.3
Gromoll, J.4
-
5
-
-
84867182661
-
LH and hCG action on the same receptor results in quantitatively and qualitatively different intracellular signalling
-
23071612
-
Casarini L Lispi M Longobardi S Milosa F La Marca A Tagliasacchi D et al. LH and hCG action on the same receptor results in quantitatively and qualitatively different intracellular signalling. PLoS One (2012) 7:e46682.10.1371/journal.pone.004668223071612
-
(2012)
PLoS One
, vol.7
, pp. e46682
-
-
Casarini, L.1
Lispi, M.2
Longobardi, S.3
Milosa, F.4
La Marca, A.5
Tagliasacchi, D.6
-
6
-
-
84922896573
-
Single molecule analysis of functionally asymmetric G protein-coupled receptor (GPCR) oligomers reveals diverse spatial and structural assemblies
-
25516594
-
Jonas KC Fanelli F Huhtaniemi IT Hanyaloglu AC. Single molecule analysis of functionally asymmetric G protein-coupled receptor (GPCR) oligomers reveals diverse spatial and structural assemblies. J Biol Chem (2015) 290:3875–92.10.1074/jbc.M114.62249825516594
-
(2015)
J Biol Chem
, vol.290
, pp. 3875-3892
-
-
Jonas, K.C.1
Fanelli, F.2
Huhtaniemi, I.T.3
Hanyaloglu, A.C.4
-
7
-
-
84895425000
-
Differences between lutropin-mediated and choriogonadotropin-mediated receptor activation
-
24438591
-
Grzesik P Teichmann A Furkert J Rutz C Wiesner B Kleinau G et al. Differences between lutropin-mediated and choriogonadotropin-mediated receptor activation. FEBS J (2014) 281:1479–92.10.1111/febs.1271824438591
-
(2014)
FEBS J
, vol.281
, pp. 1479-1492
-
-
Grzesik, P.1
Teichmann, A.2
Furkert, J.3
Rutz, C.4
Wiesner, B.5
Kleinau, G.6
-
8
-
-
0034456625
-
Male hypogonadism caused by homozygous deletion of exon 10 of the luteinizing hormone (LH) receptor: differential action of human chorionic gonadotropin and LH
-
10852464
-
Gromoll J Eiholzer U Nieschlag E Simoni M. Male hypogonadism caused by homozygous deletion of exon 10 of the luteinizing hormone (LH) receptor: differential action of human chorionic gonadotropin and LH. J Clin Endocrinol Metab (2000) 85:2281–6.10.1210/jcem.85.6.663610852464
-
(2000)
J Clin Endocrinol Metab
, vol.85
, pp. 2281-2286
-
-
Gromoll, J.1
Eiholzer, U.2
Nieschlag, E.3
Simoni, M.4
-
9
-
-
0038368875
-
Absence of exon 10 of the human luteinizing hormone (LH) receptor impairs LH, but not human chorionic gonadotropin action
-
12727981
-
Mueller T Gromoll J Simoni M Muller T. Absence of exon 10 of the human luteinizing hormone (LH) receptor impairs LH, but not human chorionic gonadotropin action. J Clin Endocrinol Metab (2003) 88:2242–9.10.1210/jc.2002-02194612727981
-
(2003)
J Clin Endocrinol Metab
, vol.88
, pp. 2242-2249
-
-
Mueller, T.1
Gromoll, J.2
Simoni, M.3
Muller, T.4
-
10
-
-
0025969701
-
Thyrotropin-luteinizing hormone/chorionic gonadotropin receptor extracellular domain chimeras as probes for thyrotropin receptor function
-
1992482
-
Nagayama Y Wadsworth HL Chazenbalk GD Russo D Seto P Rapoport B. Thyrotropin-luteinizing hormone/chorionic gonadotropin receptor extracellular domain chimeras as probes for thyrotropin receptor function. Proc Natl Acad Sci U S A (1991) 88:902–5.10.1073/pnas.88.3.9021992482
-
(1991)
Proc Natl Acad Sci U S A
, vol.88
, pp. 902-905
-
-
Nagayama, Y.1
Wadsworth, H.L.2
Chazenbalk, G.D.3
Russo, D.4
Seto, P.5
Rapoport, B.6
-
11
-
-
0026002412
-
Site-directed mutagenesis of a portion of the extracellular domain of the rat thyrotropin receptor important in autoimmune thyroid disease and nonhomologous with gonadotropin receptors. Relationship of functional and immunogenic domains
-
1655787
-
Kosugi S Ban T Akamizu T Kohn LD. Site-directed mutagenesis of a portion of the extracellular domain of the rat thyrotropin receptor important in autoimmune thyroid disease and nonhomologous with gonadotropin receptors. Relationship of functional and immunogenic domains. J Biol Chem (1991) 266:19413–8.1655787
-
(1991)
J Biol Chem
, vol.266
, pp. 19413-19418
-
-
Kosugi, S.1
Ban, T.2
Akamizu, T.3
Kohn, L.D.4
-
12
-
-
0034730516
-
Activation of the luteinizing hormone receptor following substitution of Ser-277 with selective hydrophobic residues in the ectodomain hinge region
-
10889210
-
Nakabayashi K Kudo M Kobilka B Hsueh AJW. Activation of the luteinizing hormone receptor following substitution of Ser-277 with selective hydrophobic residues in the ectodomain hinge region. J Biol Chem (2000) 275:30264–71.10.1074/jbc.M00556820010889210
-
(2000)
J Biol Chem
, vol.275
, pp. 30264-30271
-
-
Nakabayashi, K.1
Kudo, M.2
Kobilka, B.3
Hsueh, A.J.W.4
-
13
-
-
0025567011
-
Extracellular domain chimeras of the TSH and LH/CG receptors reveal the mid-region (amino acids 171-260) to play a vital role in high affinity TSH binding
-
2176485
-
Nagayama Y Russo D Chazenbalk GD Wadsworth HL Rapoport B. Extracellular domain chimeras of the TSH and LH/CG receptors reveal the mid-region (amino acids 171-260) to play a vital role in high affinity TSH binding. Biochem Biophys Res Commun (1990) 173:1150–6.10.1016/S0006-291X(05)80906-42176485
-
(1990)
Biochem Biophys Res Commun
, vol.173
, pp. 1150-1156
-
-
Nagayama, Y.1
Russo, D.2
Chazenbalk, G.D.3
Wadsworth, H.L.4
Rapoport, B.5
-
14
-
-
33645515699
-
An aromatic environment in the vicinity of serine 281 is a structural requirement for thyrotropin receptor function
-
16410307
-
Jaeschke H Neumann S Kleinau G Mueller S Claus M Krause G et al. An aromatic environment in the vicinity of serine 281 is a structural requirement for thyrotropin receptor function. Endocrinology (2006) 147:1753–60.10.1210/en.2005-113816410307
-
(2006)
Endocrinology
, vol.147
, pp. 1753-1760
-
-
Jaeschke, H.1
Neumann, S.2
Kleinau, G.3
Mueller, S.4
Claus, M.5
Krause, G.6
-
15
-
-
49649125175
-
Extended hormone binding site of the human thyroid stimulating hormone receptor: distinctive acidic residues in the hinge region are involved in bovine thyroid stimulating hormone binding and receptor activation
-
18441013
-
Mueller S Kleinau G Jaeschke H Paschke R Krause G. Extended hormone binding site of the human thyroid stimulating hormone receptor: distinctive acidic residues in the hinge region are involved in bovine thyroid stimulating hormone binding and receptor activation. J Biol Chem (2008) 283:18048–55.10.1074/jbc.M80044920018441013
-
(2008)
J Biol Chem
, vol.283
, pp. 18048-18055
-
-
Mueller, S.1
Kleinau, G.2
Jaeschke, H.3
Paschke, R.4
Krause, G.5
-
16
-
-
67650242446
-
The superagonistic activity of bovine thyroid-stimulating hormone (TSH) and the human TR1401 TSH analog is determined by specific amino acids in the hinge region of the human TSH receptor
-
19386596
-
Mueller S Kleinau G Szkudlinski MW Jaeschke H Krause G Paschke R. The superagonistic activity of bovine thyroid-stimulating hormone (TSH) and the human TR1401 TSH analog is determined by specific amino acids in the hinge region of the human TSH receptor. J Biol Chem (2009) 284:16317–24.10.1074/jbc.M109.00571019386596
-
(2009)
J Biol Chem
, vol.284
, pp. 16317-16324
-
-
Mueller, S.1
Kleinau, G.2
Szkudlinski, M.W.3
Jaeschke, H.4
Krause, G.5
Paschke, R.6
-
17
-
-
33751530407
-
Structural differences in the hinge region of the glycoprotein hormone receptors: evidence from the sulfated tyrosine residues
-
16901970
-
Bonomi M Busnelli M Persani L Vassart G Costagliola S. Structural differences in the hinge region of the glycoprotein hormone receptors: evidence from the sulfated tyrosine residues. Mol Endocrinol (2006) 20:3351–63.10.1210/me.2005-052116901970
-
(2006)
Mol Endocrinol
, vol.20
, pp. 3351-3363
-
-
Bonomi, M.1
Busnelli, M.2
Persani, L.3
Vassart, G.4
Costagliola, S.5
-
18
-
-
0033054119
-
Characterization of a region of the lutropin receptor extracellular domain near transmembrane helix 1 that is important in ligand-mediated signaling
-
10098515
-
Alvarez CA Narayan P Huang J Puett D. Characterization of a region of the lutropin receptor extracellular domain near transmembrane helix 1 that is important in ligand-mediated signaling. Endocrinology (1999) 140:1775–82.10.1210/endo.140.4.662410098515
-
(1999)
Endocrinology
, vol.140
, pp. 1775-1782
-
-
Alvarez, C.A.1
Narayan, P.2
Huang, J.3
Puett, D.4
-
19
-
-
78049446704
-
Functional differences of invariant and highly conserved residues in the extracellular domain of the glycoprotein hormone receptors
-
20736161
-
Angelova K de Jonge H Granneman JC Puett D Bogerd J. Functional differences of invariant and highly conserved residues in the extracellular domain of the glycoprotein hormone receptors. J Biol Chem (2010) 285:34813–27.10.1074/jbc.M110.14822120736161
-
(2010)
J Biol Chem
, vol.285
, pp. 34813-34827
-
-
Angelova, K.1
de Jonge, H.2
Granneman, J.C.3
Puett, D.4
Bogerd, J.5
-
20
-
-
47649089467
-
A new LH receptor splice mutation responsible for male hypogonadism with subnormal sperm production in the propositus, and infertility with regular cycles in an affected sister
-
18508780
-
Bruysters M Sultan C Auger J Faugeron I Larue L Lumbroso S et al. A new LH receptor splice mutation responsible for male hypogonadism with subnormal sperm production in the propositus, and infertility with regular cycles in an affected sister. Hum Reprod (2008) 23:1917–23.10.1093/humrep/den18018508780
-
(2008)
Hum Reprod
, vol.23
, pp. 1917-1923
-
-
Bruysters, M.1
Sultan, C.2
Auger, J.3
Faugeron, I.4
Larue, L.5
Lumbroso, S.6
-
21
-
-
80053149711
-
The hinge region of the TSH receptor stabilizes ligand binding and determines different signaling profiles of human and bovine TSH
-
21846801
-
Jaeschke H Gu R Mueller S. The hinge region of the TSH receptor stabilizes ligand binding and determines different signaling profiles of human and bovine TSH. Endocrinology (2011) 152:3986–96.10.1210/en.2011-138921846801
-
(2011)
Endocrinology
, vol.152
, pp. 3986-3996
-
-
Jaeschke, H.1
Gu, R.2
Mueller, S.3
-
22
-
-
84908577894
-
Influence of the hinge region and its adjacent domains on binding and signaling patterns of the thyrotropin and follitropin receptor
-
25340405
-
Schaarschmidt J Huth S Meier R Paschke R Jaeschke H. Influence of the hinge region and its adjacent domains on binding and signaling patterns of the thyrotropin and follitropin receptor. PLoS One (2014) 9:e111570.10.1371/journal.pone.011157025340405
-
(2014)
PLoS One
, vol.9
, pp. e111570
-
-
Schaarschmidt, J.1
Huth, S.2
Meier, R.3
Paschke, R.4
Jaeschke, H.5
-
23
-
-
54449086544
-
Asp330 and Tyr331 in the C-terminal cysteine-rich region of the luteinizing hormone receptor are key residues in hormone-induced receptor activation
-
18641392
-
Bruysters M Verhoef-Post M Themmen APN Technology M. Asp330 and Tyr331 in the C-terminal cysteine-rich region of the luteinizing hormone receptor are key residues in hormone-induced receptor activation. J Biol Chem (2008) 283:25821–8.10.1074/jbc.M80439520018641392
-
(2008)
J Biol Chem
, vol.283
, pp. 25821-25828
-
-
Bruysters, M.1
Verhoef-Post, M.2
Themmen, A.P.N.3
Technology, M.4
-
24
-
-
8744236215
-
Pharmacochaperones post-translationally enhance cell surface expression by increasing conformational stability of wild-type and mutant vasopressin V2 receptors
-
15319430
-
Wüller S Wiesner B Löffler A Furkert J Krause G Hermosilla R et al. Pharmacochaperones post-translationally enhance cell surface expression by increasing conformational stability of wild-type and mutant vasopressin V2 receptors. J Biol Chem (2004) 279:47254–63.10.1074/jbc.M40815420015319430
-
(2004)
J Biol Chem
, vol.279
, pp. 47254-47263
-
-
Wüller, S.1
Wiesner, B.2
Löffler, A.3
Furkert, J.4
Krause, G.5
Hermosilla, R.6
-
25
-
-
84906875902
-
The specific monomer/dimer equilibrium of the corticotropin-releasing factor receptor type 1 is established in the endoplasmic reticulum
-
24966326
-
Teichmann A Gibert A Lampe A Grzesik P Rutz C Furkert J et al. The specific monomer/dimer equilibrium of the corticotropin-releasing factor receptor type 1 is established in the endoplasmic reticulum. J Biol Chem (2014) 289:24250–62.10.1074/jbc.M114.55364424966326
-
(2014)
J Biol Chem
, vol.289
, pp. 24250-24262
-
-
Teichmann, A.1
Gibert, A.2
Lampe, A.3
Grzesik, P.4
Rutz, C.5
Furkert, J.6
-
26
-
-
77954455011
-
Signaling-sensitive amino acids surround the allosteric ligand binding site of the thyrotropin receptor
-
20179143
-
Kleinau G Haas A-KK Neumann S Worth CL Hoyer I Furkert J et al. Signaling-sensitive amino acids surround the allosteric ligand binding site of the thyrotropin receptor. FASEB J (2010) 24:2347–54.10.1096/fj.09-14914620179143
-
(2010)
FASEB J
, vol.24
, pp. 2347-2354
-
-
Kleinau, G.1
Haas, A.-K.K.2
Neumann, S.3
Worth, C.L.4
Hoyer, I.5
Furkert, J.6
-
27
-
-
84864502784
-
Structure of follicle-stimulating hormone in complex with the entire ectodomain of its receptor
-
22802634
-
Jiang X Liu H Chen X Chen PH Fischer D Sriraman V et al. Structure of follicle-stimulating hormone in complex with the entire ectodomain of its receptor. Proc Natl Acad Sci U S A (2012) 109:12491–6.10.1073/pnas.120664310922802634
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 12491-12496
-
-
Jiang, X.1
Liu, H.2
Chen, X.3
Chen, P.H.4
Fischer, D.5
Sriraman, V.6
-
28
-
-
84871648298
-
Extended and structurally supported insights into extracellular hormone binding, signal transduction and organization of the thyrotropin receptor
-
23300822
-
Krause G Kreuchwig A Kleinau G. Extended and structurally supported insights into extracellular hormone binding, signal transduction and organization of the thyrotropin receptor. PLoS One (2012) 7:e52920.10.1371/journal.pone.005292023300822
-
(2012)
PLoS One
, vol.7
, pp. e52920
-
-
Krause, G.1
Kreuchwig, A.2
Kleinau, G.3
-
30
-
-
36749061828
-
Template-based modeling and free modeling by I-TASSER in CASP7
-
17894355
-
Zhang Y. Template-based modeling and free modeling by I-TASSER in CASP7. Proteins (2007) 69(Suppl 8):108–17.10.1002/prot.2170217894355
-
(2007)
Proteins
, vol.69
, pp. 108-117
-
-
Zhang, Y.1
-
31
-
-
77954065271
-
I-TASSER: a unified platform for automated protein structure and function prediction
-
20360767
-
Roy A Kucukural A Zhang Y. I-TASSER: a unified platform for automated protein structure and function prediction. Nat Protoc (2010) 5:725–38.10.1038/nprot.2010.520360767
-
(2010)
Nat Protoc
, vol.5
, pp. 725-738
-
-
Roy, A.1
Kucukural, A.2
Zhang, Y.3
-
32
-
-
3242887695
-
Protein structure prediction and analysis using the Robetta server
-
15215442
-
Kim DE Chivian D Baker D. Protein structure prediction and analysis using the Robetta server. Nucleic Acids Res (2004) 32:W526–31.10.1093/nar/gkh46815215442
-
(2004)
Nucleic Acids Res
, vol.32
, pp. W526-W531
-
-
Kim, D.E.1
Chivian, D.2
Baker, D.3
-
33
-
-
79959564695
-
The IntFOLD server: an integrated web resource for protein fold recognition, 3D model quality assessment, intrinsic disorder prediction, domain prediction and ligand binding site prediction
-
21459847
-
Roche DB Buenavista MT Tetchner SJ McGuffin LJ. The IntFOLD server: an integrated web resource for protein fold recognition, 3D model quality assessment, intrinsic disorder prediction, domain prediction and ligand binding site prediction. Nucleic Acids Res (2011) 39:W171–6.10.1093/nar/gkr18421459847
-
(2011)
Nucleic Acids Res
, vol.39
, pp. W171-W176
-
-
Roche, D.B.1
Buenavista, M.T.2
Tetchner, S.J.3
McGuffin, L.J.4
-
34
-
-
84907868263
-
RaptorX server: a resource for template-based protein structure modeling
-
24573471
-
Källberg M Margaryan G Wang S Ma J Xu J. RaptorX server: a resource for template-based protein structure modeling. Methods Mol Biol (2014) 1137:17–27.10.1007/978-1-4939-0366-5_224573471
-
(2014)
Methods Mol Biol
, vol.1137
, pp. 17-27
-
-
Källberg, M.1
Margaryan, G.2
Wang, S.3
Ma, J.4
Xu, J.5
-
36
-
-
84866427649
-
Similarities and differences in interactions of thyroid stimulating and blocking autoantibodies with the TSH receptor
-
22829655
-
Núñez Miguel R Sanders J Sanders P Young S Clark J Kabelis K et al. Similarities and differences in interactions of thyroid stimulating and blocking autoantibodies with the TSH receptor. J Mol Endocrinol (2012) 49:137–51.10.1530/JME-12-004022829655
-
(2012)
J Mol Endocrinol
, vol.49
, pp. 137-151
-
-
Núñez Miguel, R.1
Sanders, J.2
Sanders, P.3
Young, S.4
Clark, J.5
Kabelis, K.6
-
37
-
-
0037084011
-
Tyrosine sulfation is required for agonist recognition by glycoprotein hormone receptors
-
11847099
-
Costagliola S Panneels V Bonomi M Koch J Many MC Smits G et al. Tyrosine sulfation is required for agonist recognition by glycoprotein hormone receptors. EMBO J (2002) 21:504–13.10.1093/emboj/21.4.50411847099
-
(2002)
EMBO J
, vol.21
, pp. 504-513
-
-
Costagliola, S.1
Panneels, V.2
Bonomi, M.3
Koch, J.4
Many, M.C.5
Smits, G.6
-
38
-
-
33644909883
-
Structural characterization of alpha-helices of implicitly solvated poly-alanine
-
16494355
-
Couch VA Cheng N Nambiar K Fink W. Structural characterization of alpha-helices of implicitly solvated poly-alanine. J Phys Chem B (2006) 110:3410–9.10.1021/jp055209j16494355
-
(2006)
J Phys Chem B
, vol.110
, pp. 3410-3419
-
-
Couch, V.A.1
Cheng, N.2
Nambiar, K.3
Fink, W.4
-
39
-
-
0034987731
-
Effects of mutations involving the highly conserved S281HCC motif in the extracellular domain of the thyrotropin (TSH) receptor on TSH binding and constitutive activity
-
11415994
-
Ho SC Van Sande J Lefort A Vassart G Costagliola S. Effects of mutations involving the highly conserved S281HCC motif in the extracellular domain of the thyrotropin (TSH) receptor on TSH binding and constitutive activity. Endocrinology (2001) 142:2760–7.10.1210/endo.142.7.824611415994
-
(2001)
Endocrinology
, vol.142
, pp. 2760-2767
-
-
Ho, S.C.1
Van Sande, J.2
Lefort, A.3
Vassart, G.4
Costagliola, S.5
-
40
-
-
84901020079
-
Human lutropin (hLH) and choriogonadotropin (CG) are assembled by different pathways: a model of hLH assembly
-
24692561
-
Bernard MP Lin W Kholodovych V Moyle WR. Human lutropin (hLH) and choriogonadotropin (CG) are assembled by different pathways: a model of hLH assembly. J Biol Chem (2014) 289:14360–9.10.1074/jbc.M113.53560924692561
-
(2014)
J Biol Chem
, vol.289
, pp. 14360-14369
-
-
Bernard, M.P.1
Lin, W.2
Kholodovych, V.3
Moyle, W.R.4
-
41
-
-
79953744598
-
Research resource: update and extension of a glycoprotein hormone receptors web application
-
21292827
-
Kreuchwig A Kleinau G Kreuchwig F Worth CL Krause G. Research resource: update and extension of a glycoprotein hormone receptors web application. Mol Endocrinol (2011) 25(4):707–12.10.1210/me.2010-051021292827
-
(2011)
Mol Endocrinol
, vol.25
, Issue.4
, pp. 707-712
-
-
Kreuchwig, A.1
Kleinau, G.2
Kreuchwig, F.3
Worth, C.L.4
Krause, G.5
-
42
-
-
84858698405
-
Insights into differential modulation of receptor function by hinge region using novel agonistic lutropin receptor and inverse agonistic thyrotropin receptor antibodies
-
22309849
-
Majumdar R Railkar R Dighe RR Mujumdar R. Insights into differential modulation of receptor function by hinge region using novel agonistic lutropin receptor and inverse agonistic thyrotropin receptor antibodies. FEBS Lett (2012) 586:810–7.10.1016/j.febslet.2012.01.05222309849
-
(2012)
FEBS Lett
, vol.586
, pp. 810-817
-
-
Majumdar, R.1
Railkar, R.2
Dighe, R.R.3
Mujumdar, R.4
|