The hinge region of the TSH receptor stabilizes ligand binding and determines different signaling profiles of human and bovine TSH

Endocrinology

Volumn 152, Issue 10, 2011, Pages 3986-3996

  Jaeschke, Holger ^a   Schaarschmidt, Jörg ^a   Günther, Robert ^a   Mueller, Sandra ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CHORIONIC GONADOTROPIN RECEPTOR; CYCLIC AMP; GUANINE NUCLEOTIDE BINDING PROTEIN; IODINE 125; LUTEINIZING HORMONE RECEPTOR; RECOMBINANT THYROTROPIN; SERPENTINE; THYROTROPIN; THYROTROPIN RECEPTOR;

ANIMAL CELL; ARTICLE; CELL SURFACE; CHIMERA; CONCENTRATION RESPONSE; CONTROLLED STUDY; GENE MUTATION; GENETIC TRANSFECTION; HINGE REGION; HORMONE ACTION; HORMONE BINDING; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN STABILITY; SECOND MESSENGER; SIGNAL TRANSDUCTION;

ANIMALS; BINDING, COMPETITIVE; CATTLE; CERCOPITHECUS AETHIOPS; COS CELLS; CYCLIC AMP; GTP-BINDING PROTEINS; HUMANS; LIGANDS; RECEPTORS, THYROTROPIN; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; THYROTROPIN;

EID: 80053149711     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2011-1389     Document Type: Article

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