Influence of the hinge region and its adjacent domains on binding and signaling patterns of the thyrotropin and follitropin receptor

PLoS ONE

Volumn 9, Issue 10, 2014, Pages

  Schaarschmidt, Jörg ^a   Huth, Sandra ^a   Meier, René ^a   Paschke, Ralf ^a   Jaeschke, Holger ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP; FOLLITROPIN RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; IODINE 125; LIGAND; THYROTROPIN RECEPTOR; FOLLITROPIN; PROTEIN BINDING; THYROTROPIN;

ARTICLE; BINDING AFFINITY; BINDING SITE; CELL SURFACE; CHIMERA; CONTROLLED STUDY; HINGE REGION; LIGAND BINDING; MOLECULAR DYNAMICS; PROTEIN DETERMINATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RECEPTOR BINDING; SIGNAL TRANSDUCTION; ANIMAL; BINDING COMPETITION; BOVINE; CELL MEMBRANE; CELL SEPARATION; CHEMISTRY; CHLOROCEBUS AETHIOPS; COS 1 CELL LINE; DOSE RESPONSE; FLOW CYTOMETRY; HUMAN; METABOLISM; MUTATION; PROTEIN TERTIARY STRUCTURE; X RAY CRYSTALLOGRAPHY;

ANIMALS; BINDING, COMPETITIVE; CATTLE; CELL MEMBRANE; CELL SEPARATION; CERCOPITHECUS AETHIOPS; COS CELLS; CRYSTALLOGRAPHY, X-RAY; CYCLIC AMP; DOSE-RESPONSE RELATIONSHIP, DRUG; FLOW CYTOMETRY; FOLLICLE STIMULATING HORMONE; HUMANS; LIGANDS; MUTATION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, FSH; RECEPTORS, THYROTROPIN; SIGNAL TRANSDUCTION; THYROTROPIN;

EID: 84908577894     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0111570     Document Type: Article

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