-
1
-
-
84882269987
-
Advancing the application of omicsbased biomarkers in environmental epidemiology
-
Vineis, P., van Veldhoven, K., Chadeau-Hyam, M. and Athersuch, T.J. (2013) Advancing the application of omicsbased biomarkers in environmental epidemiology. Environ Mol Mutagen., 54, 461-467.
-
(2013)
Environ Mol Mutagen
, vol.54
, pp. 461-467
-
-
Vineis, P.1
van Veldhoven, K.2
Chadeau-Hyam, M.3
Athersuch, T.J.4
-
2
-
-
84903934558
-
A primer series on-omic technologies for the practice of epidemiology
-
Khoury, M.J. (2014) A primer series on-omic technologies for the practice of epidemiology. Am. J. Epidemiol., 180, 127-128.
-
(2014)
Am. J. Epidemiol
, vol.180
, pp. 127-128
-
-
Khoury, M.J.1
-
3
-
-
84890546613
-
Systems genetics approaches to understand complex traits
-
Civelek, M. and Lusis, A.J. (2014) Systems genetics approaches to understand complex traits. Nat. Rev. Genet., 15, 34-48.
-
(2014)
Nat. Rev. Genet
, vol.15
, pp. 34-48
-
-
Civelek, M.1
Lusis, A.J.2
-
4
-
-
84957596540
-
Omics for prediction of environmental health effects: Blood leukocyte-based cross-omic profiling reliably predicts diseases associated with tobacco smoking
-
Georgiadis, P., Hebels, D.G., Valavanis, I., Liampa, I., Bergdahl, I.A., Johansson, A., et al. (2016) Omics for prediction of environmental health effects: Blood leukocyte-based cross-omic profiling reliably predicts diseases associated with tobacco smoking. Scientific Reports, 6, 20544.
-
(2016)
Scientific Reports
, vol.6
, pp. 20544
-
-
Georgiadis, P.1
Hebels, D.G.2
Valavanis, I.3
Liampa, I.4
Bergdahl, I.A.5
Johansson, A.6
-
5
-
-
84906838227
-
Mendelian randomization: genetic anchors for causal inference in epidemiological studies
-
Davey Smith, G. and Hemani, G. (2014) Mendelian randomization: genetic anchors for causal inference in epidemiological studies. Hum. Mol. Genet., 23(R1):R89-98.
-
(2014)
Hum. Mol. Genet
, vol.23
, Issue.R1
, pp. R89-R98
-
-
Davey Smith, G.1
Hemani, G.2
-
6
-
-
84902006099
-
Interrogating causal pathways linking genetic variants, small molecule metabolites, and circulating lipids
-
Shin, S.Y., Petersen, A.K., Wahl, S., Zhai, G., Romisch-Margl, W., Small, K.S., et al. (2014) Interrogating causal pathways linking genetic variants, small molecule metabolites, and circulating lipids. Genome Med., 6, 25.
-
(2014)
Genome Med
, vol.6
, pp. 25
-
-
Shin, S.Y.1
Petersen, A.K.2
Wahl, S.3
Zhai, G.4
Romisch-Margl, W.5
Small, K.S.6
-
7
-
-
22844446947
-
An integrative genomics approach to infer causal associations between gene expression and disease
-
Schadt, E.E., Lamb, J., Yang, X., Zhu, J., Edwards, S., Guhathakurta, D., et al. (2005) An integrative genomics approach to infer causal associations between gene expression and disease. Nat. Genet., 37, 710-717.
-
(2005)
Nat. Genet
, vol.37
, pp. 710-717
-
-
Schadt, E.E.1
Lamb, J.2
Yang, X.3
Zhu, J.4
Edwards, S.5
Guhathakurta, D.6
-
8
-
-
84964296262
-
Advances in Mediation Analysis: A Survey and Synthesis of New Developments
-
Preacher, K.J. (2015) Advances in Mediation Analysis: A Survey and Synthesis of New Developments. Annu. Rev. Psychol., 66, 825-852.
-
(2015)
Annu. Rev. Psychol
, vol.66
, pp. 825-852
-
-
Preacher, K.J.1
-
9
-
-
84964289647
-
A fatter, healthier but more unequal world
-
Davey Smith, G. (2016) A fatter, healthier but more unequal world. Lancet, 387, 1349-1350.
-
(2016)
Lancet
, vol.387
, pp. 1349-1350
-
-
Davey Smith, G.1
-
10
-
-
84924212419
-
Remnant Cholesterol, Low-Density Lipoprotein Cholesterol, and Blood Pressure as Mediators From Obesity to Ischemic Heart Disease
-
Varbo, A., Benn, M., Davey Smith, G., Timpson, N.J., Tybjaerg-Hansen, A. and Nordestgaard, B.G. (2015) Remnant Cholesterol, Low-Density Lipoprotein Cholesterol, and Blood Pressure as Mediators From Obesity to Ischemic Heart Disease. Circ. Res., 116, 665-673.
-
(2015)
Circ. Res
, vol.116
, pp. 665-673
-
-
Varbo, A.1
Benn, M.2
Davey Smith, G.3
Timpson, N.J.4
Tybjaerg-Hansen, A.5
Nordestgaard, B.G.6
-
11
-
-
84873576566
-
Epigenome-wide association data implicate DNA methylation as an intermediary of genetic risk in rheumatoid arthritis
-
Liu, Y., Aryee, M.J., Padyukov, L., Fallin, M.D., Hesselberg, E., Runarsson, A., et al. (2013) Epigenome-wide association data implicate DNA methylation as an intermediary of genetic risk in rheumatoid arthritis. Nat. Biotechnol., 31, 142-147.
-
(2013)
Nat. Biotechnol
, vol.31
, pp. 142-147
-
-
Liu, Y.1
Aryee, M.J.2
Padyukov, L.3
Fallin, M.D.4
Hesselberg, E.5
Runarsson, A.6
-
12
-
-
84942646677
-
DNAmethylation mediates the effect of maternal smoking during pregnancy on birthweight of the offspring
-
Kupers, L.K., Xu, X.L., Jankipersadsing, S.A., Vaez, A., la Bastidevan Gemert, S., Scholtens, S., et al. (2015) DNAmethylation mediates the effect of maternal smoking during pregnancy on birthweight of the offspring. Int. J. Epidemiol., 44, 1224-1237.
-
(2015)
Int. J. Epidemiol
, vol.44
, pp. 1224-1237
-
-
Kupers, L.K.1
Xu, X.L.2
Jankipersadsing, S.A.3
Vaez, A.4
la Bastidevan Gemert, S.5
Scholtens, S.6
-
13
-
-
84965118964
-
Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation
-
Kato, N., Loh, M., Takeuchi, F., Verweij, N., Wang, X., Zhang, W.H., et al. (2015) Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation. Nat. Genet., 47, 1282-1282.
-
(2015)
Nat. Genet
, vol.47
, pp. 1282-1282
-
-
Kato, N.1
Loh, M.2
Takeuchi, F.3
Verweij, N.4
Wang, X.5
Zhang, W.H.6
-
14
-
-
84928819497
-
An epigenome-wide association study of total serum immunoglobulin E concentration
-
Liang, L.M., Willis-Owen, S.A.G., Laprise, C., Wong, K.C.C., Davies, G.A., Hudson, T.J., et al. (2015) An epigenome-wide association study of total serum immunoglobulin E concentration. Nature, 520, 670-U188.
-
(2015)
Nature
, vol.520
-
-
Liang, L.M.1
Willis-Owen, S.A.G.2
Laprise, C.3
Wong, K.C.C.4
Davies, G.A.5
Hudson, T.J.6
-
15
-
-
84950107042
-
Hypomethylation of smokingrelated genes is associated with future lung cancer in four prospective cohorts
-
Fasanelli, F., Baglietto, L., Ponzi, E., Guida, F., Campanella, G., Johansson, M., et al. (2015) Hypomethylation of smokingrelated genes is associated with future lung cancer in four prospective cohorts. Nat. Commun, 6, 10192.
-
(2015)
Nat. Commun
, vol.6
, pp. 10192
-
-
Fasanelli, F.1
Baglietto, L.2
Ponzi, E.3
Guida, F.4
Campanella, G.5
Johansson, M.6
-
16
-
-
84923658758
-
Genome-wide association study identifies peanut allergy-specific loci and evidence of epigenetic mediation in US children
-
Hong, X.M., Hao, K., Ladd-Acosta, C., Hansen, K.D., Tsai, H.J., Liu, X., et al. (2015) Genome-wide association study identifies peanut allergy-specific loci and evidence of epigenetic mediation in US children. Nat. Commun, 6, 6304.
-
(2015)
Nat. Commun
, vol.6
, pp. 6304
-
-
Hong, X.M.1
Hao, K.2
Ladd-Acosta, C.3
Hansen, K.D.4
Tsai, H.J.5
Liu, X.6
-
17
-
-
84982168491
-
A statistical framework to model the meeting-in-the-middle principle using metabolomic data: application to hepatocellular carcinoma in the EPIC study
-
Assi, N., Fages, A., Vineis, P., Chadeau-Hyam, M., Stepien, M., Duarte-Salles, T., et al. (2015) A statistical framework to model the meeting-in-the-middle principle using metabolomic data: application to hepatocellular carcinoma in the EPIC study. Mutagenesis, 30, 743-753.
-
(2015)
Mutagenesis
, vol.30
, pp. 743-753
-
-
Assi, N.1
Fages, A.2
Vineis, P.3
Chadeau-Hyam, M.4
Stepien, M.5
Duarte-Salles, T.6
-
18
-
-
84885859371
-
DNA Hypomethylation, Ambient Particulate Matter, and Increased Blood Pressure: Findings From Controlled Human Exposure Experiments
-
Bellavia, A., Urch, B., Speck, M., Brook, R.D., Scott, J.A., Albetti, B., et al. (2013) DNA Hypomethylation, Ambient Particulate Matter, and Increased Blood Pressure: Findings From Controlled Human Exposure Experiments. J. Am. Heart. Assoc., 2, e000212.
-
(2013)
J. Am. Heart. Assoc
, vol.2
-
-
Bellavia, A.1
Urch, B.2
Speck, M.3
Brook, R.D.4
Scott, J.A.5
Albetti, B.6
-
19
-
-
0023020183
-
Themoderator-mediator variable distinction in social psychological research: conceptual, strategic, and statistical considerations
-
Baron, R.M. and Kenny, D.A. (1986) Themoderator-mediator variable distinction in social psychological research: conceptual, strategic, and statistical considerations. J. Pers. Soc Psychol., 51, 1173-1182.
-
(1986)
J. Pers. Soc Psychol
, vol.51
, pp. 1173-1182
-
-
Baron, R.M.1
Kenny, D.A.2
-
20
-
-
70949095633
-
Beyond Baron and Kenny: Statistical Mediation Analysis in the New Millennium
-
Hayes, A.F. (2009) Beyond Baron and Kenny: Statistical Mediation Analysis in the New Millennium. Commun. Monogr., 76, 408-420.
-
(2009)
Commun. Monogr
, vol.76
, pp. 408-420
-
-
Hayes, A.F.1
-
21
-
-
78650085125
-
A General Approach to Causal Mediation Analysis
-
Imai, K., Keele, L. and Tingley, D. (2010) A General Approach to Causal Mediation Analysis. Psychol. Methods, 15, 309-334.
-
(2010)
Psychol. Methods
, vol.15
, pp. 309-334
-
-
Imai, K.1
Keele, L.2
Tingley, D.3
-
22
-
-
84862151653
-
The Role of Measurement Error and Misclassification in Mediation Analysis Mediation and Measurement Error
-
VanderWeele, T.J., Valeri, L. and Ogburn, E.L. (2012) The Role of Measurement Error and Misclassification in Mediation Analysis Mediation and Measurement Error. Epidemiology, 23, 561-564.
-
(2012)
Epidemiology
, vol.23
, pp. 561-564
-
-
VanderWeele, T.J.1
Valeri, L.2
Ogburn, E.L.3
-
23
-
-
84862122133
-
Quantification of Bias in Direct Effects Estimates Due to Different Types of Measurement Error in the Mediator
-
le Cessie, S., Debeij, J., Rosendaal, F.R., Cannegieter, S.C. and Vandenbroucke, J.P. (2012) Quantification of Bias in Direct Effects Estimates Due to Different Types of Measurement Error in the Mediator. Epidemiology, 23, 551-560.
-
(2012)
Epidemiology
, vol.23
, pp. 551-560
-
-
le Cessie, S.1
Debeij, J.2
Rosendaal, F.R.3
Cannegieter, S.C.4
Vandenbroucke, J.P.5
-
24
-
-
84895838196
-
Misclassification of the mediator matters when estimating indirect effects
-
Blakely, T., McKenzie, S. and Carter, K. (2013) Misclassification of the mediator matters when estimating indirect effects. J. Epidemiol. Community Health, 67, 458-466.
-
(2013)
J. Epidemiol. Community Health
, vol.67
, pp. 458-466
-
-
Blakely, T.1
McKenzie, S.2
Carter, K.3
-
26
-
-
84873406544
-
A three-way decomposition of a total effect into direct, indirect, and interactive effects
-
VanderWeele, T.J. (2013) A three-way decomposition of a total effect into direct, indirect, and interactive effects. Epidemiology, 24, 224-232.
-
(2013)
Epidemiology
, vol.24
, pp. 224-232
-
-
VanderWeele, T.J.1
-
27
-
-
84877870559
-
Tobacco smoking leads to extensive genome-wide changes in DNA methylation
-
Zeilinger, S., Kuhnel, B., Klopp, N., Baurecht, H., Kleinschmidt, A., Gieger, C., et al. (2013) Tobacco smoking leads to extensive genome-wide changes in DNA methylation. Plos One, 8, e63812.
-
(2013)
Plos One
, vol.8
-
-
Zeilinger, S.1
Kuhnel, B.2
Klopp, N.3
Baurecht, H.4
Kleinschmidt, A.5
Gieger, C.6
-
28
-
-
84940566107
-
A quantitative epigenetic approach for the assessment of cigarette consumption
-
Philibert, R., Hollenbeck, N., Andersen, E., Osborn, T., Gerrard, M., Gibbons, F.X., et al. (2015) A quantitative epigenetic approach for the assessment of cigarette consumption. Front Psychol, 6, 656.
-
(2015)
Front Psychol
, vol.6
, pp. 656
-
-
Philibert, R.1
Hollenbeck, N.2
Andersen, E.3
Osborn, T.4
Gerrard, M.5
Gibbons, F.X.6
-
29
-
-
67650258730
-
Disentangling molecular relationships with a causal inference test
-
Millstein, J., Zhang, B., Zhu, J. and Schadt, E.E. (2009) Disentangling molecular relationships with a causal inference test. BMC Genet, 10, 23.
-
(2009)
BMC Genet
, vol.10
, pp. 23
-
-
Millstein, J.1
Zhang, B.2
Zhu, J.3
Schadt, E.E.4
-
30
-
-
42949144555
-
Harnessing naturally randomized transcription to infer regulatory relationships among genes
-
Chen, L.S., Emmert-Streib, F. and Storey, J.D. (2007) Harnessing naturally randomized transcription to infer regulatory relationships among genes. Genome Biol., 8, R219.
-
(2007)
Genome Biol
, vol.8
, pp. R219
-
-
Chen, L.S.1
Emmert-Streib, F.2
Storey, J.D.3
-
31
-
-
84991457654
-
Cit: hypothesis testing software for mediation analysis in genomic applications
-
Millstein, J., Chen, G.K. and Breton, C.V. (2016) cit: hypothesis testing software for mediation analysis in genomic applications. Bioinformatics, pii: btw135.
-
(2016)
Bioinformatics
-
-
Millstein, J.1
Chen, G.K.2
Breton, C.V.3
-
32
-
-
0037322022
-
Mendelian randomization': can genetic epidemiology contribute to understanding environmental determinants of disease?
-
Davey Smith, G. and Ebrahim, S. (2003) 'Mendelian randomization': can genetic epidemiology contribute to understanding environmental determinants of disease? Int. J. Epidemiol., 32, 1-22.
-
(2003)
Int. J. Epidemiol
, vol.32
, pp. 1-22
-
-
Davey Smith, G.1
Ebrahim, S.2
-
33
-
-
84994143756
-
Integrative genomic analysis identifies epigenetic marks that mediate genetic risk for epithelial ovarian cancer
-
Koestler, D.C., Chalise, P., Cicek, M.S., Cunningham, J.M., Armasu, S., Larson, M.C., et al. (2014) Integrative genomic analysis identifies epigenetic marks that mediate genetic risk for epithelial ovarian cancer. Cancer Res., 74.
-
(2014)
Cancer Res
, pp. 74
-
-
Koestler, D.C.1
Chalise, P.2
Cicek, M.S.3
Cunningham, J.M.4
Armasu, S.5
Larson, M.C.6
-
34
-
-
0035956651
-
Sifting the evidencewhat's wrong with significance tests?
-
Sterne, J.A. and Davey Smith, G. (2001) Sifting the evidencewhat's wrong with significance tests? BMJ, 322, 226-231.
-
(2001)
BMJ
, vol.322
, pp. 226-231
-
-
Sterne, J.A.1
Davey Smith, G.2
-
35
-
-
84969596203
-
Diagnostic yield of sequencing familial hypercholesterolemia genes in patients with severe hypercholesterolemia
-
Khera, A.V., Won, H.H., Peloso, G.M., Lawson, K.S., Bartz, T.M., Deng, X., et al. (2016) Diagnostic yield of sequencing familial hypercholesterolemia genes in patients with severe hypercholesterolemia. J. Am. Coll. Cardiol., 67(22):2578-2589.
-
(2016)
J. Am. Coll. Cardiol
, vol.67
, Issue.22
, pp. 2578-2589
-
-
Khera, A.V.1
Won, H.H.2
Peloso, G.M.3
Lawson, K.S.4
Bartz, T.M.5
Deng, X.6
-
36
-
-
84943182742
-
The UK10K project identifies rare variants in health and disease
-
The UK10K Consortium UK (2015) The UK10K project identifies rare variants in health and disease. Nature, 526, 82-90.
-
(2015)
Nature
, vol.526
, pp. 82-90
-
-
-
37
-
-
75149163834
-
Unraveling the Directional Link between Adiposity and Inflammation: A Bidirectional Mendelian Randomization Approach
-
Welsh, P., Polisecki, E., Robertson, M., Jahn, S., Buckley, B.M., de Craen, A.J.M., et al. (2010) Unraveling the Directional Link between Adiposity and Inflammation: A Bidirectional Mendelian Randomization Approach. J. Clin. Endocr. Metab., 95, 93-99.
-
(2010)
J. Clin. Endocr. Metab
, vol.95
, pp. 93-99
-
-
Welsh, P.1
Polisecki, E.2
Robertson, M.3
Jahn, S.4
Buckley, B.M.5
de Craen, A.J.M.6
-
38
-
-
79951677811
-
C-reactive protein levels and body mass index: elucidating direction of causation through reciprocal Mendelian randomization
-
Timpson, N.J., Nordestgaard, B.G., Harbord, R.M., Zacho, J., Frayling, T.M., Tybjaerg-Hansen, A., et al. (2011) C-reactive protein levels and body mass index: elucidating direction of causation through reciprocal Mendelian randomization. Int. J. Obes., 35, 300-308.
-
(2011)
Int. J. Obes
, vol.35
, pp. 300-308
-
-
Timpson, N.J.1
Nordestgaard, B.G.2
Harbord, R.M.3
Zacho, J.4
Frayling, T.M.5
Tybjaerg-Hansen, A.6
-
39
-
-
1942436221
-
Mendelian randomization: prospects, potentials, and limitations
-
Davey Smith, G. and Ebrahim, S. (2004) Mendelian randomization: prospects, potentials, and limitations. Int. J. Epidemiol., 33, 30-42.
-
(2004)
Int. J. Epidemiol
, vol.33
, pp. 30-42
-
-
Davey Smith, G.1
Ebrahim, S.2
-
40
-
-
34547682094
-
Mendelian randomization as an instrumental variable approach to causal inference
-
Didelez, V. and Sheehan, N. (2007) Mendelian randomization as an instrumental variable approach to causal inference. Stat. Methods Med. Res., 16, 309-330.
-
(2007)
Stat. Methods Med. Res
, vol.16
, pp. 309-330
-
-
Didelez, V.1
Sheehan, N.2
-
41
-
-
40849083720
-
Mendelian randomization: using genes as instruments for making causal inferences in epidemiology
-
Lawlor, D.A., Harbord, R.M., Sterne, J.A., Timpson, N. and Davey Smith, G. (2008) Mendelian randomization: using genes as instruments for making causal inferences in epidemiology. Stat. Med., 27, 1133-1163.
-
(2008)
Stat. Med
, vol.27
, pp. 1133-1163
-
-
Lawlor, D.A.1
Harbord, R.M.2
Sterne, J.A.3
Timpson, N.4
Davey Smith, G.5
-
42
-
-
78149381194
-
Epigenetic epidemiology of common complex disease: prospects for prediction, prevention, and treatment
-
Relton, C.L. and Davey Smith, G. (2010) Epigenetic epidemiology of common complex disease: prospects for prediction, prevention, and treatment. PLoS Med, 7, e1000356.
-
(2010)
PLoS Med
, vol.7
-
-
Relton, C.L.1
Davey Smith, G.2
-
43
-
-
84858648623
-
Two-step epigenetic Mendelian randomization: a strategy for establishing the causal role of epigenetic processes in pathways to disease
-
Relton, C.L. and Davey Smith, G. (2012) Two-step epigenetic Mendelian randomization: a strategy for establishing the causal role of epigenetic processes in pathways to disease. Int. J. Epidemiol., 41, 161-176.
-
(2012)
Int. J. Epidemiol
, vol.41
, pp. 161-176
-
-
Relton, C.L.1
Davey Smith, G.2
-
44
-
-
84862258323
-
Prenatal nutrition, epigenetics and schizophrenia risk: can we test causal effects?
-
Kirkbride, J.B., Susser, E., Kundakovic, M., Kresovich, J.K., Davey Smith, G. and Relton, C.L. (2012) Prenatal nutrition, epigenetics and schizophrenia risk: can we test causal effects? Epigenomics, 4, 303-315.
-
(2012)
Epigenomics
, vol.4
, pp. 303-315
-
-
Kirkbride, J.B.1
Susser, E.2
Kundakovic, M.3
Kresovich, J.K.4
Davey Smith, G.5
Relton, C.L.6
-
45
-
-
84936776179
-
Network Mendelian randomization: using genetic variants as instrumental variables to investigate mediation in causal pathways
-
Burgess, S., Daniel, R.M., Butterworth, A.S., Thompson, S.G. and Consortium, E.-I.A. (2015) Network Mendelian randomization: using genetic variants as instrumental variables to investigate mediation in causal pathways. Int. J. Epidemiol., 44, 484-495.
-
(2015)
Int. J. Epidemiol
, vol.44
, pp. 484-495
-
-
Burgess, S.1
Daniel, R.M.2
Butterworth, A.S.3
Thompson, S.G.4
Consortium, E.-I.A.5
-
46
-
-
84926681140
-
Epigenomic annotation of genetic variants using the Roadmap Epigenome Browser
-
Zhou, X., Li, D.F., Zhang, B., Lowdon, R.F., Rockweiler, N.B., Sears, R.L., et al. (2015) Epigenomic annotation of genetic variants using the Roadmap Epigenome Browser. Nat. Biotechnol., 33, 345-346.
-
(2015)
Nat. Biotechnol
, vol.33
, pp. 345-346
-
-
Zhou, X.1
Li, D.F.2
Zhang, B.3
Lowdon, R.F.4
Rockweiler, N.B.5
Sears, R.L.6
-
47
-
-
84961927084
-
Integration of summary data from GWAS and eQTL studies predicts complex trait gene targets
-
Zhu, Z., Zhang, F., Hu, H., Bakshi, A., Robinson, M.R., Powell, J.E., et al. (2016) Integration of summary data from GWAS and eQTL studies predicts complex trait gene targets. Nat. Genet., 48, 481-487.
-
(2016)
Nat. Genet
, vol.48
, pp. 481-487
-
-
Zhu, Z.1
Zhang, F.2
Hu, H.3
Bakshi, A.4
Robinson, M.R.5
Powell, J.E.6
-
48
-
-
84959547986
-
Integrative approaches for large-scale transcriptome-wide association studies
-
Gusev, A., Ko, A., Shi, H., Bhatia, G., Chung, W., Penninx, B.W., et al. (2016) Integrative approaches for large-scale transcriptome-wide association studies. Nat. Genet., 48, 245-252.
-
(2016)
Nat. Genet
, vol.48
, pp. 245-252
-
-
Gusev, A.1
Ko, A.2
Shi, H.3
Bhatia, G.4
Chung, W.5
Penninx, B.W.6
-
49
-
-
84925089678
-
The role of regulatory variation in complex traits and disease
-
Albert, F.W. and Kruglyak, L. (2015) The role of regulatory variation in complex traits and disease. Nat. Rev. Genet., 16, 197-212.
-
(2015)
Nat. Rev. Genet
, vol.16
, pp. 197-212
-
-
Albert, F.W.1
Kruglyak, L.2
-
50
-
-
84884973036
-
Efficient Design for Mendelian Randomization Studies: Subsample and 2-Sample Instrumental Variable Estimators
-
Pierce, B.L. and Burgess, S. (2013) Efficient Design for Mendelian Randomization Studies: Subsample and 2-Sample Instrumental Variable Estimators. Am. J. Epidemiol., 178, 1177-1184.
-
(2013)
Am. J. Epidemiol
, vol.178
, pp. 1177-1184
-
-
Pierce, B.L.1
Burgess, S.2
-
51
-
-
84962675367
-
Best (but oft-forgotten) practices: the design, analysis, and interpretation of Mendelian randomization studies
-
Haycock, P.C., Burgess, S., Wade, K.H., Bowden, J., Relton, C. and Davey Smith, G. (2016) Best (but oft-forgotten) practices: the design, analysis, and interpretation of Mendelian randomization studies. Am. J. Clin. Nutr., 103, 965-978.
-
(2016)
Am. J. Clin. Nutr
, vol.103
, pp. 965-978
-
-
Haycock, P.C.1
Burgess, S.2
Wade, K.H.3
Bowden, J.4
Relton, C.5
Davey Smith, G.6
-
52
-
-
84935901897
-
Beyond the single SNP: emerging developments in Mendelian randomization in the "Omics" era
-
Brion, M.-J.A., Benyamin, B., Visscher, P.M. and Davey Smith, G. (2014) Beyond the single SNP: emerging developments in Mendelian randomization in the "Omics" era. Curr. Epidemiol. Rep., 1, 228-236.
-
(2014)
Curr. Epidemiol. Rep
, vol.1
, pp. 228-236
-
-
Brion, M.-J.A.1
Benyamin, B.2
Visscher, P.M.3
Davey Smith, G.4
-
53
-
-
84860431510
-
Quantitative high-throughput metabolomics: a new era in epidemiology and genetics
-
Ala-Korpela, M., Kangas, A.J. and Soininen, P. (2012) Quantitative high-throughput metabolomics: a new era in epidemiology and genetics. Genome Med., 4, 36.
-
(2012)
Genome Med
, vol.4
, pp. 36
-
-
Ala-Korpela, M.1
Kangas, A.J.2
Soininen, P.3
-
54
-
-
84857648463
-
Genome-wide association study identifies multiple loci influencing human serum metabolite levels
-
Kettunen, J., Tukiainen, T., Sarin, A.P., Ortega-Alonso, A., Tikkanen, E., Lyytikainen, L.P., et al. (2012) Genome-wide association study identifies multiple loci influencing human serum metabolite levels. Nat. Genet., 44, 269-276.
-
(2012)
Nat. Genet
, vol.44
, pp. 269-276
-
-
Kettunen, J.1
Tukiainen, T.2
Sarin, A.P.3
Ortega-Alonso, A.4
Tikkanen, E.5
Lyytikainen, L.P.6
-
55
-
-
85015350236
-
Systematic identification of genetic influences on methylation across the human life course
-
Gaunt, T.R., Shihab, H.A., Hemani, G., Min, J.L., Woodward, G., Lyttleton, O., et al. (2016) Systematic identification of genetic influences on methylation across the human life course. Genome Biol., 17, 61.
-
(2016)
Genome Biol
, vol.17
, pp. 61
-
-
Gaunt, T.R.1
Shihab, H.A.2
Hemani, G.3
Min, J.L.4
Woodward, G.5
Lyttleton, O.6
-
56
-
-
84878682420
-
The Genotype-Tissue Expression (GTEx) project
-
Consortium, G.T. (2013) The Genotype-Tissue Expression (GTEx) project. Nat. Genet., 45, 580-585.
-
(2013)
Nat. Genet
, vol.45
, pp. 580-585
-
-
Consortium, G.T.1
-
57
-
-
0038736116
-
An analysis of the "pleiotropic" effects of a new lethal mutation in the rat (Mus norvegicus)
-
Gruneberg, H. (1938) An analysis of the "pleiotropic" effects of a new lethal mutation in the rat (Mus norvegicus). Proc. R. Soc. Ser. B-Bio., 125, 123-144.
-
(1938)
Proc. R. Soc. Ser. B-Bio
, vol.125
, pp. 123-144
-
-
Gruneberg, H.1
-
58
-
-
0031800626
-
Seven types of pleiotropy
-
Hodgkin, J. (1998) Seven types of pleiotropy. Int. J. Dev. Biol., 42, 501-505.
-
(1998)
Int. J. Dev. Biol
, vol.42
, pp. 501-505
-
-
Hodgkin, J.1
-
59
-
-
79951799418
-
The pleiotropic structure of the genotype-phenotype map: the evolvability of complex organisms
-
Wagner, G.P. and Zhang, J.Z. (2011) The pleiotropic structure of the genotype-phenotype map: the evolvability of complex organisms. Nat. Rev. Genet., 12, 204-213.
-
(2011)
Nat. Rev. Genet
, vol.12
, pp. 204-213
-
-
Wagner, G.P.1
Zhang, J.Z.2
-
60
-
-
84879419343
-
Pleiotropy in complex traits: challenges and strategies
-
Solovieff, N., Cotsapas, C., Lee, P.H., Purcell, S.M. and Smoller, J.W. (2013) Pleiotropy in complex traits: challenges and strategies. Nat. Rev. Genet., 14, 483-495.
-
(2013)
Nat. Rev. Genet
, vol.14
, pp. 483-495
-
-
Solovieff, N.1
Cotsapas, C.2
Lee, P.H.3
Purcell, S.M.4
Smoller, J.W.5
-
61
-
-
84871260146
-
Effect of long-term exposure to lower low-density lipoprotein cholesterol beginning early in life on the risk of coronary heart disease: A Mendelian randomization analysis
-
Ference, B.A., Yoo, W., Alesh, I., Mahajan, N., Mirowska, K.K., Mewada, A., et al. (2012) Effect of long-term exposure to lower low-density lipoprotein cholesterol beginning early in life on the risk of coronary heart disease: A Mendelian randomization analysis. J. Am. Coll. Cardiol., 60, 2631-2639.
-
(2012)
J. Am. Coll. Cardiol
, vol.60
, pp. 2631-2639
-
-
Ference, B.A.1
Yoo, W.2
Alesh, I.3
Mahajan, N.4
Mirowska, K.K.5
Mewada, A.6
-
62
-
-
84936755918
-
Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression
-
Bowden, J., Davey Smith, G. and Burgess, S. (2015) Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression. Int. J. Epidemiol., 44, 512-525.
-
(2015)
Int. J. Epidemiol
, vol.44
, pp. 512-525
-
-
Bowden, J.1
Davey Smith, G.2
Burgess, S.3
-
63
-
-
84963670568
-
Consistent Estimation in Mendelian Randomization with Some Invalid Instruments Using a Weighted Median Estimator
-
Bowden, J., Davey Smith, G., Haycock, P.C. and Burgess, S. (2016) Consistent Estimation in Mendelian Randomization with Some Invalid Instruments Using a Weighted Median Estimator. Genet. Epidemiol., 40, 304-314.
-
(2016)
Genet. Epidemiol
, vol.40
, pp. 304-314
-
-
Bowden, J.1
Davey Smith, G.2
Haycock, P.C.3
Burgess, S.4
-
64
-
-
84936758183
-
Multivariable Mendelian randomization: the use of pleiotropic genetic variants to estimate causal effects.Am
-
Burgess, S. and Thompson, S.G. (2015) Multivariable Mendelian randomization: the use of pleiotropic genetic variants to estimate causal effects.Am. J. Epidemiol., 181, 251-260.
-
(2015)
J. Epidemiol
, vol.181
, pp. 251-260
-
-
Burgess, S.1
Thompson, S.G.2
-
65
-
-
0026739615
-
Confounding in epidemiological studies: why "independent" effects may not be all they seem
-
Davey Smith, G. and Phillips, A.N. (1992) Confounding in epidemiological studies: why "independent" effects may not be all they seem. BMJ, 305, 757-759.
-
(1992)
BMJ
, vol.305
, pp. 757-759
-
-
Davey Smith, G.1
Phillips, A.N.2
-
66
-
-
0000957052
-
Tests for comparing elements of a correlation matrix
-
Steiger, J.H. (1980) Tests for comparing elements of a correlation matrix. Psychol. Bull., 87, 245-251.
-
(1980)
Psychol. Bull
, vol.87
, pp. 245-251
-
-
Steiger, J.H.1
-
67
-
-
0001589778
-
Correlation and causation Part I. Method of path coefficients
-
Wright, S. (1920) Correlation and causation Part I. Method of path coefficients. J. Agric. Res., 20, 0557-0585.
-
(1920)
J. Agric. Res
, vol.20
, pp. 0557-0585
-
-
Wright, S.1
-
68
-
-
40249097457
-
Reflections on mediation
-
Kenny, D.A. (2008) Reflections on mediation. Organ. Res. Methods, 11, 353-358.
-
(2008)
Organ. Res. Methods
, vol.11
, pp. 353-358
-
-
Kenny, D.A.1
-
69
-
-
85017142215
-
Probabilistic computational causal discovery for systems biology
-
Geris L, Gomez-Cabrero D, editors. New York City: Springer
-
Lagani, V., Ball, G., Tegner, J. and Tsamardinos, I. Probabilistic computational causal discovery for systems biology In: Geris L, Gomez-Cabrero D, editors. Uncertainty in Biology, A Computational Modeling Approach. Studies in Mechanobiology, Tissue Engineering and Biomaterials. 17. New York City: Springer; 2015.
-
(2015)
Uncertainty in Biology, A Computational Modeling Approach. Studies in Mechanobiology, Tissue Engineering and Biomaterials
, vol.17
-
-
Lagani, V.1
Ball, G.2
Tegner, J.3
Tsamardinos, I.4
-
70
-
-
84898050170
-
Methodological challenges in mendelian randomization
-
VanderWeele, T.J., Tchetgen Tchetgen, E.J., Cornelis, M. and Kraft, P. (2014) Methodological challenges in mendelian randomization. Epidemiology, 25, 427-435.
-
(2014)
Epidemiology
, vol.25
, pp. 427-435
-
-
VanderWeele, T.J.1
Tchetgen Tchetgen, E.J.2
Cornelis, M.3
Kraft, P.4
-
71
-
-
84867606063
-
The effect of nondifferential measurement error on bias, precision and power in Mendelian randomization studies
-
Pierce, B.L. and VanderWeele, T.J. (2012) The effect of nondifferential measurement error on bias, precision and power in Mendelian randomization studies. Int. J. Epidemiol., 41, 1383-1393.
-
(2012)
Int. J. Epidemiol
, vol.41
, pp. 1383-1393
-
-
Pierce, B.L.1
VanderWeele, T.J.2
|