Hypomethylation of smoking-related genes is associated with future lung cancer in four prospective cohorts

Nature Communications

Volumn 6, Issue , 2015, Pages

  Fasanelli, Francesca ^a,b   Baglietto, Laura ^c,d,e,f   Ponzi, Erica ^a   Guida, Florence ^g   Campanella, Gianluca ^g   Johansson, Mattias ^h,i   Grankvist, Kjell ⁱ   Johansson, Mikael ⁱ   Assumma, Manuela Bianca ^a   Naccarati, Alessio ^a   Chadeau Hyam, Marc ^g   Ala, Ugo ^b   Faltus, Christian ^j   Kaaks, Rudolf ^j,k   Risch, Angela ^j,k,l   De Stavola, Bianca ^m   Hodge, Allison ^e   Giles, Graham G ^e,f   Southey, Melissa C ^f   Relton, Caroline L ⁿ   Haycock, Philip C ⁿ   Lund, Eiliv ^o   Polidoro, Silvia ^a   Sandanger, Torkjel M ^o   Severi, Gianluca ^a,c,d,e,f   Vineis, Paolo ^a,g   more..

^a Human Genetics Foundation   (Italy)

^b UNIVERSITY OF TURIN   (Italy)

^c INSERM   (France)

^d UNIVERSITÉ PARIS SACLAY   (France)

^e CANCER EPIDEMIOLOGY CENTRE   (Australia)

^f UNIVERSITY OF MELBOURNE   (Australia)

^g IMPERIAL COLLEGE LONDON   (United Kingdom)

^h INTERNATIONAL AGENCY FOR RESEARCH ON CANCER   (France)

ⁱ UMEÅ UNIVERSITY   (Sweden)

^j GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^k MEMBER OF THE GERMAN CENTER FOR LUNG RESEARCH DZL   (Germany)

^l UNIVERSITY OF SALZBURG   (Austria)

^m LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

ⁿ UNIVERSITY OF BRISTOL   (United Kingdom)

^o UNIVERSITY OF TROMSØ   (Norway)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ARYL HYDROCARBON RECEPTOR REPRESSOR; DNA; PROTEIN; PROTEINASE ACTIVATED RECEPTOR 4; UNCLASSIFIED DRUG;

CANCER; COHORT ANALYSIS; DNA; GENE; HEALTH RISK; METHYLATION; SMOKING;

ADULT; AGED; ARTICLE; BLOOD SAMPLING; CANCER RISK; CASE CONTROL STUDY; CLINICAL ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; FEMALE; GENE EXPRESSION; GENETIC ASSOCIATION; HUMAN; LUNG CANCER; PREDICTIVE VALUE; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; RISK ASSESSMENT; SMOKING; SMOKING CESSATION; SMOKING HABIT; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION; GENETICS; LUNG TUMOR; MALE; MIDDLE AGED; ODDS RATIO; PHYSIOLOGY;

NICOTIANA TABACUM;

ADULT; AGED; COHORT STUDIES; CPG ISLANDS; FEMALE; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION TO DISEASE; HUMANS; LUNG NEOPLASMS; MALE; MIDDLE AGED; ODDS RATIO; SMOKING;

EID: 84950107042     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms10192     Document Type: Article

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