TREM2/DAP12 signal elicits proinflammatory response in microglia and exacerbates neuropathic pain

Journal of Neuroscience

Volumn 36, Issue 43, 2016, Pages 11138-11150

  Kobayashi, Masaaki ^a   Konishi, Hiroyuki ^a   Sayo, Akira ^a   Takai, Toshiyuki ^b   Kiyama, Hiroshi ^a  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b TOHOKU UNIVERSITY   (Japan)

Author keywords

Dap12; Microglia; Pain; Trem2

Indexed keywords

KILLER CELL ACTIVATING RECEPTOR ASSOCIATED PROTEIN; TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2; AUTACOID; IMMUNOGLOBULIN RECEPTOR; MEMBRANE PROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TREM2 PROTEIN, MOUSE; TYROBP PROTEIN, MOUSE;

ANALYSIS OF VARIANCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIOR CHANGE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; FLOW CYTOMETRY; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MALE; MICROGLIA; MOUSE; NEUROPATHIC PAIN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; SIGNAL TRANSDUCTION; ANIMAL; C57BL MOUSE; IMMUNOLOGY; NEURALGIA; PATHOLOGY; SPINAL CORD; SPINAL CORD INJURY;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; INFLAMMATION MEDIATORS; MALE; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL; MICROGLIA; NEURALGIA; RECEPTORS, IMMUNOLOGIC; SIGNAL TRANSDUCTION; SPINAL CORD; SPINAL CORD INJURIES;

EID: 84992754386     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1238-16.2016     Document Type: Article

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