A DAP12-Dependent signal promotes pro-inflammatory polarization in microglia following nerve injury and exacerbates degeneration of injured neurons

GLIA

Volumn 63, Issue 6, 2015, Pages 1073-1082

  Kobayashi, Masaaki ^a   Konishi, Hiroyuki ^a   Takai, Toshiyuki ^b   Kiyama, Hiroshi ^a  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b TOHOKU UNIVERSITY   (Japan)

Author keywords

Axotomy; Inflammation; ITAM; Motor neuron; Neuron death; Neurotoxicity

Indexed keywords

CYTOKINE; KILLER CELL ACTIVATING RECEPTOR ASSOCIATED PROTEIN; LIPOPOLYSACCHARIDE; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TYROBP PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; HYPOGLOSSAL NERVE INJURY; INFLAMMATION; MALE; MICROGLIA; MOTONEURON; MOUSE; NERVE CELL; NERVE CELL NECROSIS; NERVE DEGENERATION; NERVE FIBER TRANSECTION; NERVE INJURY; NONHUMAN; PHENOTYPE; POLARIZATION; PRIORITY JOURNAL; ANIMAL; C57BL MOUSE; CELL COUNT; CELL CULTURE; CELL DEATH; DISEASE MODEL; GENETICS; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; TIME;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CELL COUNT; CELL DEATH; CELLS, CULTURED; CYTOKINES; DISEASE MODELS, ANIMAL; HYPOGLOSSAL NERVE INJURIES; LIPOPOLYSACCHARIDES; MALE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROGLIA; MOTOR NEURONS; NERVE DEGENERATION; TIME FACTORS;

EID: 84927973984     PISSN: 08941491     EISSN: 10981136     Source Type: Journal    
DOI: 10.1002/glia.22802     Document Type: Article

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