Downregulation of NEDD9 by apigenin suppresses migration, invasion, and metastasis of colorectal cancer cells

Toxicology and Applied Pharmacology

Volumn 311, Issue , 2016, Pages 106-112

  Dai, Jin ^a   Van Wie, Peter G ^a   Fai, Leonard Yenwong ^a   Kim, Donghern ^a   Wang, Lei ^b   Poyil, Pratheeshkumar ^b   Luo, Jia ^a   Zhang, Zhuo ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Apigenin; Colorectal cancer; Invasion; Metastasis; Migration; NEDD9

Indexed keywords

ANTINEOPLASTIC AGENT; APIGENIN; FOCAL ADHESION KINASE; NEURAL PRECURSOR CELL EXPRESSED DEVELOPMENTALLY DOWNREGULATED 9 PROTEIN; PROTEIN KINASE B; PROTEIN KINASE P60; SCAFFOLD PROTEIN; UNCLASSIFIED DRUG; NEDD9 PROTEIN, HUMAN; PHOSPHOPROTEIN; PROTEIN TYROSINE KINASE; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL INVASION; CELL MIGRATION; COLORECTAL CARCINOMA; CONTROLLED STUDY; DOWN REGULATION; ENZYME PHOSPHORYLATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; METASTASIS; ANIMAL; COLORECTAL TUMOR; DRUG EFFECTS; FEMALE; METABOLISM; MOUSE; NUDE MOUSE; PATHOLOGY; PHOSPHORYLATION; SIGNAL TRANSDUCTION; TUMOR CELL LINE; TUMOR INVASION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; APIGENIN; CELL LINE, TUMOR; COLORECTAL NEOPLASMS; DOWN-REGULATION; FEMALE; FOCAL ADHESION PROTEIN-TYROSINE KINASES; HUMANS; MICE; MICE, NUDE; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES;

EID: 84992377644     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2016.09.016     Document Type: Article

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