Apigenin induces apoptosis in human leukemia cells and exhibits anti-leukemic activity In Vivo

Molecular Cancer Therapeutics

Volumn 11, Issue 1, 2012, Pages 132-142

  Budhraja, Amit ^a   Gao, Ning ^a,d   Zhang, Zhuo ^b   Son, Young Ok ^a   Cheng, Senping ^a   Wang, Xin ^a   Ding, Songze ^a   Hitron, Andrew ^a   Chen, Gang ^a   Luo, Jia ^a   Shi, Xianglin ^a,c  

^a UNIVERSITY OF KENTUCKY   (United States)

^b UNIVERSITY OF KENTUCKY COLLEGE OF PUBLIC HEALTH   (United States)

^c UNIVERSITY OF KENTUCKY   (United States)

^d THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; APIGENIN; CASPASE 3; CASPASE 7; CASPASE 9; CYTOCHROME C; JANUS KINASE; PROTEIN BCL 2; PROTEIN KINASE B; PROTEIN MCL 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CONTROLLED STUDY; DOWN REGULATION; DRUG POTENTIATION; ENZYME ACTIVATION; ENZYME INACTIVATION; ENZYME RELEASE; HUMAN; HUMAN CELL; IN VIVO STUDY; INTRACELLULAR SIGNALING; LEUKEMIA; LEUKEMIA CELL; MITOCHONDRION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; TUMOR XENOGRAFT;

ANIMALS; APIGENIN; APOPTOSIS; CASPASES; CELL LINE, TUMOR; CHROMONES; CYTOCHROMES C; DOWN-REGULATION; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; JURKAT CELLS; LEUKEMIA; MICE; MICE, NUDE; MITOCHONDRIA; MORPHOLINES; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-BCL-2; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; U937 CELLS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84862928682     PISSN: 15357163     EISSN: 15388514     Source Type: Journal    
DOI: 10.1158/1535-7163.MCT-11-0343     Document Type: Article

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