5,6-Dichloro-ribifuranosylbenzimidazole- and apigenin-induced sensitization of colon cancer cells to TNF-α-mediated apoptosis

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 285, Issue 5 48-5, 2003, Pages

  Farah, Myriam ^a   Parhar, Kuljit ^a   Moussavi, Maryam ^a   Eivemark, Sharlene ^a   Salh, Baljinder ^a,b  

^a JACK BELL RESEARCH CENTRE   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Apoptosis; CK2; Manganese superoxide dismutase; Nuclear factor B; Tumor necrosis factor

Indexed keywords

5,6 DICHLOROBENZIMIDAZOLE RIBOSIDE; APIGENIN; CASEIN KINASE II; CASPASE 3; DNA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MANGANESE SUPEROXIDE DISMUTASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN KINASE INHIBITOR; PROTEIN SERINE THREONINE KINASE; RNA; TUMOR NECROSIS FACTOR ALPHA;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL DEATH; CELL SURVIVAL; COLON CANCER; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INHIBITION; FLUORESCENCE ACTIVATED CELL SORTING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; REPORTER GENE;

EID: 0142182047     PISSN: 01931857     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpgi.00205.2003     Document Type: Article

References (46)

1. Allende JE and Allende CC. Protein kinases. 4. Protein kinase CK2: an enzyme with multiple substrates and a puzzling regulation. FASEB J 9: 313-323, 1995.
2. Baeuerle PA and Baltimore D. NF-kappa B: ten years after. Cell 87: 13-20, 1996.
3. Baldwin AS Jr. The NF-kappa B and I kappa B proteins: new discoveries and insights. Annu Rev Immunol 14: 649-683, 1996.
4. Baud V and Karin M. Signal transduction by tumor necrosis factor and its relatives. Trends Cell Biol 11: 372-377, 2001.
5. Beg AA and Baltimore D. An essential role for NF-kappaB in preventing TNF-alpha-induced cell death. Science 274: 782-784, 1996.
6. Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72: 248-254, 1976.
7. Carswell EA, Old LJ, Kassel RL, Green S, Fiore N, and Williamson B. An endotoxin-induced serum factor that causes necrosis of tumors. Proc Natl Acad Sci USA 72: 3666-3670, 1975.
8. Chen C, Edelstein LC, and Gelinas C. The Rel/NF-kappaB family directly activates expression of the apoptosis inhibitor Bcl-x(L). Mol Cell Biol 20: 2687-2695, 2000.
9. Cusack JC Jr, Liu R, and Baldwin AS Jr. Inducible chemoresistance to 7-ethyl-10-[4-(1-piperidino)-1-piperidino]-carbonyloxycamptothe cin (CPT-11) in colorectal cancer cells and a xenograft model is overcome by inhibition of nuclear factor-kappaB activation. Cancer Res 60: 2323-2330, 2000.
10. Delhalle S, Deregowski V, Benoit V, Merville MP, and Bours V. NF-kappaB-dependent MnSOD expression protects adenocarcinoma cells from TNF-alpha-induced apoptosis. Oncogene 21: 3917-3924, 2002.
11. De Smaele E, Zazzeroni F, Papa S, Nguyen DU, Jin R, Jones J, Cong R, and Franzoso G. Induction of gadd45beta by NF-kappaB downregulates pro-apoptotic JNK signalling. Nature 414:308-313, 2001.
12. Desagher S, Osen-Sand A, Montessuit S, Magnenat E, Vilbois F, Hochmann A, Journot L, Antonsson B, and Martinou JC. Phosphorylation of bid by casein kinases I and II regulates its cleavage by caspase 8. Mol Cell 8: 601-611, 2001.
13. Gapany M, Faust RA, Tawfic S, Davis A, Adams GL, and Ahmed K. Association of elevated protein kinase CK2 activity with aggressive behavior of squamous cell carcinoma of the head and neck. Mol Med 1: 659-666, 1995.
14. Garg A and Aggarwal BB. Nuclear transcription factor-kappaB as a target for cancer drug development. Leukemia 16: 1053-1068, 2002.
15. Ghavidel A and Schultz MC. Casein kinase II regulation of yeast TFIIIB is mediated by the TATA-binding protein. Genes Dev 11: 2780-2789, 1997.
16. Guerra B and Issinger OG. Protein kinase CK2 and its role in cellular proliferation, development and pathology. Electrophoresis 20: 391-408, 1999.
17. Guo C, Yu S, Davis AT, Wang H, Green JE, and Ahmed K. A potential role of nuclear matrix-associated protein kinase CK2 in protection against drug-induced apoptosis in cancer cells. J Biol Chem 276: 5992-5999, 2001.
18. Karin M, Cao Y, Greten FR, and Li ZW. NF-kappaB in cancer: from innocent bystander to major culprit. Nat Rev Cancer 2: 301-310, 2002.
19. Landesman-Bollag E, Channavajhala PL, Cardiff RD, and Seldin DC. p53 deficiency and misexpression of protein kinase CK2alpha collaborate in the development of thymic lymphomas in mice. Oncogene 16: 2965-2974, 1998.
20. Landesman-Bollag E, Romieu-Mourez R, Song DH, Sonenshein GE, Cardiff RD, and Seldin DC. Protein kinase CK2 in mammary gland tumorigenesis. Oncogene 20: 3247-3257, 2001.
21. Li P, Li J, Muller E, Otto A, Dietz R, and von Harsdorf R. Phosphorylation by protein kinase CK2. A signaling switch for the caspase-inhibiting protein ARC. Mol Cell 10: 247, 2002.
22. Lin R, Beauparlant P, Makris C, Meloche S, and Hiscott J. Phosphorylation of IkappaBalpha in the C-terminal PEST domain by casein kinase II affects intrinsic protein stability. Mol Cell Biol 16: 1401-1409, 1996.
23. McElhinny JA, Trushin SA, Bren GD, Chester N, and Paya CV. Casein kinase II phosphorylates I kappa B alpha at S-283, S-289, S-293, and T-291 and is required for its degradation. Mol Cell Biol 16: 899-906, 1996.
24. Mitev V, Miteva L, Botev I, and Houdebine LM. Enhanced casein kinase II activity in metastatic melanoma. J Dermatol Sci 8: 45-49, 1994.
25. Munstermann U, Fritz G, Seitz G, Lu YP, Schneider HR, and Issinger OG. Casein kinase II is elevated in solid human tumours and rapidly proliferating non-neoplastic tissue. Eur J Biochem 189: 251-257, 1990.
26. Pinna LA and Meggio F. Protein kinase CK2 ("casein kinase-2") and its implication in cell division and proliferation. Prog Cell Cycle Res 3: 77-97, 1997.
27. Prowald K, Fischer H, and Issinger OG. Enhanced casein kinase II activity in human tumour cell cultures. FEBS Lett 176: 479-483, 1984.
28. Romieu-Mourez R, Landesman-Bollag E, Seldin DC, Traish AM, Mercurio F, and Sonenshein GE. Roles of IKK kinases and protein kinase CK2 in activation of nuclear factor-kappaB in breast cancer. Cancer Res 61: 3810-3818, 2001.
29. a.Salh B, Assi K, Templeman V, Parhar K, Owen D, Gomez-Munoz A, and Jacobson K. Curcumin attenuates DNB-induced colitis. Am J Physiol Gastrointest Liver Physiol 285: G235-G243, 2003.
30. Sayed M, Kim SO, Salh BS, Issinger OG, and Pelech SL. Stress-induced activation of protein kinase CK2 by direct interaction with p38 mitogen-activated protein kinase. J Biol Chem 275:16569-16573, 2000.
31. Schoonbroodt S, Ferreira V, Best-Belpomme M, Boelaert JR, Legrand-Poels S, Korner M, and Piette J. Crucial role of the amino-terminal tyrosine residue 42 and the carboxyl-terminal PEST domain of I kappa B alpha in NF-kappa B activation by an oxidative stress. J Immunol 164: 4292-4300, 2000.
32. Schwarz EM, Van Antwerp D, and Verma IM. Constitutive phosphorylation of IkappaBalpha by casein kinase II occurs preferentially at serine 293: requirement for degradation of free IkappaBalpha. Mol Cell Biol 16: 3554-3559, 1996.
33. Song DH, Sussman DJ, and Seldin DC. Endogenous protein kinase CK2 participates in Wnt signaling in mammary epithelial cells. J Biol Chem 275: 23790-23797, 2000.
34. Sugarman BJ, Aggarwal BB, Hass PE, Figari IS, Palladino MA Jr, and Shepard HM. Recombinant human tumor necrosis factor-alpha: effects on proliferation of normal and transformed cells in vitro. Science 230: 943-945, 1985.
35. Tang G, Minemoto Y, Dibling B, Purcell NH, Li Z, Karin M, and Lin A. Inhibition of JNK activation through NF-kappaB target genes. Nature 414: 313-317, 2001.
36. Tawfic S, Yu S, Wang H, Faust R, Davis A, and Ahmed K. Protein kinase CK2 signal in neoplasia. Histol Histopathol 16: 573-582, 2001.
37. Taylor JA, Bren GD, Pennington KN, Trushin SA, Asin S, and Paya CV. Serine 32 and serine 36 of IkappaBalpha are directly phosphorylated by protein kinase CKII in vitro. J Mol Biol 290: 839-850, 1999.
38. Van Antwerp DJ, Martin SJ, Kafri T, Green DR, and Verma IM. Suppression of TNF-alpha-induced apoptosis by NF-kappaB. Science 274: 787-789, 1996.
39. Van Lint J, Agostinis P, Vandevoorde V, Haegeman G, Fiers W, Merlevede W, and Vandenheede JR. Tumor necrosis factor stimulates multiple serine/threonine protein kinases in Swiss 3T3 and L929 cells. Implication of casein kinase-2 and extracellular signal-regulated kinases in the tumor necrosis factor signal transduction pathway. J Biol Chem 267: 25916-25921, 1992.
40. Wang CY, Guttridge DC, Mayo MW, and Baldwin AS Jr. NF-kappaB induces expression of the Bcl-2 homologue A1/Bfl-1 to preferentially suppress chemotherapy-induced apoptosis. Mol Cell Biol 19: 5923-5929, 1999.
41. Wang CY, Mayo MW, and Baldwin AS Jr. TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB. Science 274: 784-787, 1996.
42. Wang CY, Mayo MW, Korneluk RG, Goeddel DV, and Baldwin AS Jr. NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation. Science 281: 1680-1683, 1998.
43. Wang D, Westerheide SD, Hanson JL, and Baldwin AS Jr. Tumor necrosis factor alpha-induced phosphorylation of RelA/p65 on Ser529 is controlled by casein kinase II. J Biol Chem 275: 32592-32597, 2000.
44. Zandomeni R, Zandomeni MC, Shugar D, and Weinmann R. Casein kinase type II is involved in the inhibition by 5,6-dichloro-l-beta-D-ribofuranosylbenzimidazole of specific RNA polymerase II transcription. J Biol Chem 261: 3414-3419, 1986.
45. Zhang L, Yu J, Park BH, Kinzler KW, and Vogelstein B. Role of BAX in the apoptotic response to anticancer agents. Science 290: 989-992, 2000.
46. Zong WX, Edelstein LC, Chen C, Bash J, and Gelinas C. The prosurvival Bcl-2 homolog Bfl-1/A1 is a direct transcriptional target of NF-kappaB that blocks TNFalpha-induced apoptosis. Genes Dev 13: 382-387, 1999.