Inhibition of hedgehog signaling decreases proliferation and clonogenicity of human mesenchymal stem cells

PLoS ONE

Volumn 6, Issue 2, 2011, Pages

  Plaisant, Magali ^a,b   Giorgetti Peraldi, Sophie ^b,c   Gabrielson, Marike ^a,b   Loubat, Agnes ^b   Dani, Christian ^a,b   Peraldi, Pascal ^a,b  

^a CENTRE DE BIOCHIMIE   (France)

^b UNIVERSITÉ CÔTE D'AZUR   (France)

^c INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN A; MITOGEN ACTIVATED PROTEIN KINASE; RETINOBLASTOMA PROTEIN; SONIC HEDGEHOG PROTEIN; CYCLOPAMINE; GLI2 PROTEIN, HUMAN; KRUPPEL LIKE FACTOR; NUCLEAR PROTEIN; SMALL INTERFERING RNA; TERATOGENIC AGENT; VERATRUM ALKALOID;

ARTICLE; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL DIFFERENTIATION; CELL PROLIFERATION; CLONOGENESIS; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; MESENCHYMAL STEM CELL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; CELL CLONE; CELL CULTURE; CELL SURVIVAL; CLONOGENIC ASSAY; CYTOLOGY; DOSE RESPONSE; DOWN REGULATION; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; METABOLISM; PHYSIOLOGY;

ERINACEIDAE;

CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; CLONE CELLS; COLONY-FORMING UNITS ASSAY; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; HEDGEHOG PROTEINS; HUMANS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MESENCHYMAL STEM CELLS; NUCLEAR PROTEINS; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TERATOGENS; VERATRUM ALKALOIDS;

EID: 79751507662     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0016798     Document Type: Article

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