3H-1,2-dithiole-3-thione as a novel therapeutic agent for the treatment of experimental autoimmune encephalomyelitis

Brain, Behavior, and Immunity

Volumn 57, Issue , 2016, Pages 173-186

  Kuo, Ping Chang ^a   Brown, Dennis A ^b   Scofield, Barbara A ^a   Yu, I Chen ^a   Chang, Fen Lei ^a   Wang, Pei Yu ^c   Yen, Jui Hung ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MANCHESTER UNIVERSITY   (United States)

^c NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

D3T; Dendritic cells; Microglia; MS EAE; Th1 Th17

Indexed keywords

1,2 DITHIOLE 3 THIONE DERIVATIVE; 3H 1,2 DITHIOLE 3 THIONE; B7 ANTIGEN; CD40 ANTIGEN; CD86 ANTIGEN; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HEME OXYGENASE 1; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 12; INTERLEUKIN 12P35; INTERLEUKIN 12P40; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 23; INTERLEUKIN 23P19; INTERLEUKIN 6; MESSENGER RNA; TRANSCRIPTION FACTOR FOXP3; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG; 1,2-DITHIOL-3-THIONE; ANTIINFLAMMATORY AGENT; THIOKETONE; THIOPHENE DERIVATIVE;

ADAPTIVE IMMUNITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; DISEASE COURSE; DISEASE EXACERBATION; DISEASE SEVERITY; DRUG EFFECT; DRUG EFFICACY; ENZYME INDUCTION; EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS; FEMALE; IN VITRO STUDY; INNATE IMMUNITY; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTIC INFILTRATION; MICROGLIA; MOUSE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TH1 CELL; TH17 CELL; ANIMAL; C57BL MOUSE; DRUG EFFECTS; TRANSGENIC MOUSE;

ANIMALS; ANTI-INFLAMMATORY AGENTS; DENDRITIC CELLS; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MICROGLIA; TH1 CELLS; TH17 CELLS; THIONES; THIOPHENES;

EID: 84992223440     PISSN: 08891591     EISSN: 10902139     Source Type: Journal    
DOI: 10.1016/j.bbi.2016.03.015     Document Type: Article

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