-
1
-
-
79961032414
-
Liver ischemia and reperfusion injury: New insights into mechanisms of innate-adaptive immune- mediated tissue inflammation
-
Zhai Y, Busuttil RW, Kupiec-Weglinski JW. (2011) Liver ischemia and reperfusion injury: new insights into mechanisms of innate-adaptive immune- mediated tissue inflammation. Am. J. Transplant. 11:1563–9.
-
(2011)
Am. J. Transplant
, vol.11
, pp. 1563-1569
-
-
Zhai, Y.1
Busuttil, R.W.2
Kupiec-Weglinski, J.W.3
-
2
-
-
84855958437
-
HO-1-STAT3 axis in mouse liver ischemia/reperfusion injury: Regulation of TLR4 innate responses through PI3K/PTEN signaling
-
Ke B, et al. (2012) HO-1-STAT3 axis in mouse liver ischemia/reperfusion injury: regulation of TLR4 innate responses through PI3K/PTEN signaling. J. Hepatol. 56:359–66.
-
(2012)
J. Hepatol
, vol.56
, pp. 359-366
-
-
Ke, B.1
-
3
-
-
10344264453
-
Cutting edge: TLR4 activation mediates liver ischemia/reperfusion inflammatory response via IFN regulatory factor 3-dependent MyD88-independent pathway
-
Zhai Y, et al. (2004) Cutting edge: TLR4 activation mediates liver ischemia/reperfusion inflammatory response via IFN regulatory factor 3-dependent MyD88-independent pathway. J. Immunol. 173:7115–9.
-
(2004)
J. Immunol
, vol.173
, pp. 7115-7119
-
-
Zhai, Y.1
-
4
-
-
0036019201
-
Heme oxygenase 1 gene transfer prevents CD95/Fas ligand-mediated apoptosis and improves liver allograft survival via carbon monoxide signaling pathway
-
Ke B, et al. (2002) Heme oxygenase 1 gene transfer prevents CD95/Fas ligand-mediated apoptosis and improves liver allograft survival via carbon monoxide signaling pathway. Hum. Gene Ther. 13:1189–99.
-
(2002)
Hum. Gene Ther
, vol.13
, pp. 1189-1199
-
-
Ke, B.1
-
5
-
-
0033452790
-
Upregulation of heme oxygenase- 1 protects genetically fat Zucker rat livers from ischemia/reperfusion injury
-
Amersi F, et al. (1999) Upregulation of heme oxygenase- 1 protects genetically fat Zucker rat livers from ischemia/reperfusion injury. J. Clin. Invest. 104:1631–9.
-
(1999)
J. Clin. Invest
, vol.104
, pp. 1631-1639
-
-
Amersi, F.1
-
6
-
-
0041861336
-
Cytoprotective and antiapoptotic effects of IL-13 in hepatic cold ischemia/ reperfusion injury are heme oxygenase-1 dependent
-
Ke B, et al. (2003) Cytoprotective and antiapoptotic effects of IL-13 in hepatic cold ischemia/ reperfusion injury are heme oxygenase-1 dependent. Am. J. Transplant. 3:1076–82.
-
(2003)
Am. J. Transplant
, vol.3
, pp. 1076-1082
-
-
Ke, B.1
-
7
-
-
34248200101
-
Viral interleukin-10 gene transfer prevents liver ischemia-reperfusion injury: Toll-like receptor-4 and heme oxygenase-1 signaling in innate and adaptive immunity
-
Ke B, et al. (2007) Viral interleukin-10 gene transfer prevents liver ischemia-reperfusion injury: Toll-like receptor-4 and heme oxygenase-1 signaling in innate and adaptive immunity. Hum. Gene Ther. 18:355–66.
-
(2007)
Hum. Gene Ther
, vol.18
, pp. 355-366
-
-
Ke, B.1
-
8
-
-
0035401243
-
Heme oxygenase-1 overexpression protects rat livers from ischemia/reperfusion injury with extended cold preservation
-
Kato H, et al. (2001) Heme oxygenase-1 overexpression protects rat livers from ischemia/reperfusion injury with extended cold preservation. Am. J. Transplant. 1:121–8.
-
(2001)
Am. J. Transplant
, vol.1
, pp. 121-128
-
-
Kato, H.1
-
9
-
-
9244220097
-
Early stress protein gene expression in a human model of ischemic preconditioning
-
Patel A, et al. (2004) Early stress protein gene expression in a human model of ischemic preconditioning. Transplantation. 78:1479–87.
-
(2004)
Transplantation
, vol.78
, pp. 1479-1487
-
-
Patel, A.1
-
10
-
-
58149235092
-
Tissue-resident macrophages protect the liver from ischemia reperfusion injury via a heme oxygenase-1-dependent mechanism
-
Devey L, et al. (2009) Tissue-resident macrophages protect the liver from ischemia reperfusion injury via a heme oxygenase-1-dependent mechanism. Mol. Ther. 17:65–72.
-
(2009)
Mol. Ther
, vol.17
, pp. 65-72
-
-
Devey, L.1
-
11
-
-
0034665324
-
Induction of heme oxygenase-1 expression in macrophages by diesel exhaust particle chemicals and quinones via the antioxidantresponsive element
-
Li N, et al. (2000) Induction of heme oxygenase-1 expression in macrophages by diesel exhaust particle chemicals and quinones via the antioxidantresponsive element. J. Immunol. 165:3393–401.
-
(2000)
J. Immunol
, vol.165
, pp. 3393-3401
-
-
Li, N.1
-
12
-
-
0031577292
-
An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements
-
Itoh K, et al. (1997) An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements. Biochem. Biophys. Res. Commun. 236:313–22.
-
(1997)
Biochem. Biophys. Res. Commun
, vol.236
, pp. 313-322
-
-
Itoh, K.1
-
13
-
-
37549050907
-
Heme oxygenase- 1 induction by NRF2 requires inactivation of the transcriptional repressor BACH1
-
Reichard JF, Motz GT, Puga A. (2007) Heme oxygenase- 1 induction by NRF2 requires inactivation of the transcriptional repressor BACH1. Nucleic Acids Res. 35:7074–86.
-
(2007)
Nucleic Acids Res
, vol.35
, pp. 7074-7086
-
-
Reichard, J.F.1
Motz, G.T.2
Puga, A.3
-
14
-
-
84867034260
-
Role of nrf2 in oxidative stress and toxicity
-
Ma Q. (2013) Role of nrf2 in oxidative stress and toxicity. Annu. Rev. Pharmacol. Toxicol. 53:401–26.
-
(2013)
Annu. Rev. Pharmacol. Toxicol
, vol.53
, pp. 401-426
-
-
Ma, Q.1
-
15
-
-
0042330074
-
Identification of a novel Nrf2- regulated antioxidant response element (ARE) in the mouse NAD(P)H:Quinone oxidoreductase 1 gene: Reassessment of the ARE consensus sequence
-
Nioi P, McMahon M, Itoh K, Yamamoto M, Hayes JD. (2003) Identification of a novel Nrf2- regulated antioxidant response element (ARE) in the mouse NAD(P)H:quinone oxidoreductase 1 gene: reassessment of the ARE consensus sequence. Biochem. J. 374:337–48.
-
(2003)
Biochem. J
, vol.374
, pp. 337-348
-
-
Nioi, P.1
McMahon, M.2
Itoh, K.3
Yamamoto, M.4
Hayes, J.D.5
-
16
-
-
0037821802
-
Keap1-dependent proteasomal degradation of transcription factor Nrf2 contributes to the negative regulation of antioxidant response element-driven gene expression
-
McMahon M, Itoh K, Yamamoto M, Hayes JD. (2003) Keap1-dependent proteasomal degradation of transcription factor Nrf2 contributes to the negative regulation of antioxidant response element-driven gene expression. J. Biol. Chem. 278:21592–600.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 21592-21600
-
-
McMahon, M.1
Itoh, K.2
Yamamoto, M.3
Hayes, J.D.4
-
17
-
-
67649402187
-
The Nrf2- antioxidant response element signaling pathway and its activation by oxidative stress
-
Nguyen T, Nioi P, Pickett CB. (2009) The Nrf2- antioxidant response element signaling pathway and its activation by oxidative stress. J. Biol. Chem. 284:13291–5.
-
(2009)
J. Biol. Chem
, vol.284
, pp. 13291-13295
-
-
Nguyen, T.1
Nioi, P.2
Pickett, C.B.3
-
18
-
-
84884542277
-
Nrf2 signalling promotes ex vivo tubular epithelial cell survival and regeneration via murine double minute (MDM)-2
-
Hagemann JH, Thomasova D, Mulay SR, Anders HJ. (2013) Nrf2 signalling promotes ex vivo tubular epithelial cell survival and regeneration via murine double minute (MDM)-2. Nephrol. Dial. Transplant. 28:2028–37.
-
(2013)
Nephrol. Dial. Transplant
, vol.28
, pp. 2028-2037
-
-
Hagemann, J.H.1
Thomasova, D.2
Mulay, S.R.3
Ers, H.J.4
-
19
-
-
0036007313
-
Role of NRF2 in protection against hyperoxic lung injury in mice
-
Cho HY, et al. (2002) Role of NRF2 in protection against hyperoxic lung injury in mice. Am. J. Respir. Cell Mol. Biol. 26:175–82.
-
(2002)
Am. J. Respir. Cell Mol. Biol
, vol.26
, pp. 175-182
-
-
Cho, H.Y.1
-
20
-
-
60549084888
-
Genetic ablation of Nrf2 enhances susceptibility to acute lung injury after traumatic brain injury in mice
-
Jin W, et al. (2009) Genetic ablation of Nrf2 enhances susceptibility to acute lung injury after traumatic brain injury in mice. Exp. Biol. Med. (Maywood). 234:181–9.
-
(2009)
Exp. Biol. Med. (Maywood)
, vol.234
, pp. 181-189
-
-
Jin, W.1
-
21
-
-
84921895179
-
Committee on Care and Use of Laboratory Animals. (1985)
-
Institute of Laboratory Animal Resources (U.S.), Bethesda (MD): NIH. 83 pp. (NIH publication; no. 85-23)
-
Institute of Laboratory Animal Resources (U.S.), Committee on Care and Use of Laboratory Animals. (1985) Guide for the Care and Use of Laboratory Animals. Rev. 1985. Bethesda (MD): NIH. 83 pp. (NIH publication; no. 85-23).
-
(1985)
Guide for the Care and Use of Laboratory Animals. Rev
-
-
-
22
-
-
0036677208
-
CD154-CD40 T-cell costimulation pathway is required in the mechanism of hepatic ischemia/reperfusion injury, and its blockade facilitates and depends on heme oxygenase- 1 mediated cytoprotection
-
Shen XD, et al. (2002) CD154-CD40 T-cell costimulation pathway is required in the mechanism of hepatic ischemia/reperfusion injury, and its blockade facilitates and depends on heme oxygenase- 1 mediated cytoprotection. Transplantation. 74:315–9.
-
(2002)
Transplantation
, vol.74
, pp. 315-319
-
-
Shen, X.D.1
-
23
-
-
77952008630
-
Adoptive transfer of ex vivo HO-1 modified bone marrow-derived macrophages prevents liver ischemia and reperfusion injury
-
Ke B, et al. (2010) Adoptive transfer of ex vivo HO-1 modified bone marrow-derived macrophages prevents liver ischemia and reperfusion injury. Mol. Ther. 18:1019–25.
-
(2010)
Mol. Ther
, vol.18
, pp. 1019-1025
-
-
Ke, B.1
-
24
-
-
0027319824
-
Neutrophil infiltration as an important factor in liver ischemia and reperfusion injury: Modulating effects of FK506 and cyclosporine
-
Suzuki S, Toledo-Pereyra LH, Rodriguez FJ, Cejalvo D. (1993) Neutrophil infiltration as an important factor in liver ischemia and reperfusion injury: modulating effects of FK506 and cyclosporine. Transplantation. 55:1265–72.
-
(1993)
Transplantation
, vol.55
, pp. 1265-1272
-
-
Suzuki, S.1
Toledo-Pereyra, L.H.2
Rodriguez, F.J.3
Cejalvo, D.4
-
25
-
-
0021998590
-
Myeloperoxidase activity as a quantitative assessment of neutrophil infiltration into ischemic myocardium
-
Mullane KM, Kraemer R, Smith B. (1985) Myeloperoxidase activity as a quantitative assessment of neutrophil infiltration into ischemic myocardium. J. Pharmacol. Methods. 14:157–67.
-
(1985)
J. Pharmacol. Methods
, vol.14
, pp. 157-167
-
-
Mullane, K.M.1
Kraemer, R.2
Smith, B.3
-
26
-
-
84863137323
-
Notch signal suppresses Tolllike receptor-triggered inflammatory responses in macrophages by inhibiting extracellular signalegulated kinase 1/2-mediated nuclear factor kappaB activation
-
Zhang Q, et al. (2012) Notch signal suppresses Tolllike receptor-triggered inflammatory responses in macrophages by inhibiting extracellular signalegulated kinase 1/2-mediated nuclear factor kappaB activation. J. Biol. Chem. 287:6208–17.
-
(2012)
J. Biol. Chem
, vol.287
, pp. 6208-6217
-
-
Zhang, Q.1
-
27
-
-
77649273272
-
Nrf2 the rescue: Effects of the antioxidative/electrophilic response on the liver
-
Klaassen CD, Reisman SA. (2010) Nrf2 the rescue: effects of the antioxidative/electrophilic response on the liver. Toxicol. Appl. Pharmacol. 244:57–65.
-
(2010)
Toxicol. Appl. Pharmacol
, vol.244
, pp. 57-65
-
-
Klaassen, C.D.1
Reisman, S.A.2
-
28
-
-
57649213538
-
The Nrf2-ARE pathway: An indicator and modulator of oxidative stress in neurodegeneration
-
Johnson JA, et al. (2008) The Nrf2-ARE pathway: an indicator and modulator of oxidative stress in neurodegeneration. Ann. N. Y. Acad. Sci. 1147:61–9.
-
(2008)
Ann. N. Y. Acad. Sci
, vol.1147
, pp. 61-69
-
-
Johnson, J.A.1
-
29
-
-
4444315787
-
A strategy for cancer prevention: Stimulation of the Nrf2-ARE signaling pathway
-
Zhang Y, Gordon GB. (2004) A strategy for cancer prevention: stimulation of the Nrf2-ARE signaling pathway. Mol. Cancer Ther. 3:885–93.
-
(2004)
Mol. Cancer Ther
, vol.3
, pp. 885-893
-
-
Zhang, Y.1
Gordon, G.B.2
-
30
-
-
33845655925
-
Role of Bach1 and Nrf2 in up-regulation of the heme oxygenase-1 gene by cobalt protoporphyrin
-
Shan Y, Lambrecht RW, Donohue SE, Bonkovsky HL. (2006) Role of Bach1 and Nrf2 in up-regulation of the heme oxygenase-1 gene by cobalt protoporphyrin. FASEB J. 20:2651–3.
-
(2006)
FASEB J
, vol.20
, pp. 2651-2653
-
-
Shan, Y.1
Lambrecht, R.W.2
Donohue, S.E.3
Bonkovsky, H.L.4
-
31
-
-
0036127426
-
Heme oxygenase-1 mediates the anti-inflammatory effect of interleukin-10 in mice
-
Lee TS, Chau LY. (2002) Heme oxygenase-1 mediates the anti-inflammatory effect of interleukin-10 in mice. Nat. Med. 8:240–6.
-
(2002)
Nat. Med
, vol.8
, pp. 240-246
-
-
Lee, T.S.1
Chau, L.Y.2
-
32
-
-
84887997385
-
KEAP1-NRF2 complex in ischemia- induced hepatocellular damage of mouse liver transplants
-
Ke B, et al. (2013) KEAP1-NRF2 complex in ischemia- induced hepatocellular damage of mouse liver transplants. J. Hepatol. 59:1200–7.
-
(2013)
J. Hepatol
, vol.59
, pp. 1200-1207
-
-
Ke, B.1
-
33
-
-
58149181985
-
Lipopolysaccharide-induced expression of NAD(P)H:Quinone oxidoreductase 1 and heme oxygenase-1 protects against excessive inflammatory responses in human monocytes
-
Rushworth SA, MacEwan DJ, O’Connell MA. (2008) Lipopolysaccharide-induced expression of NAD(P)H:quinone oxidoreductase 1 and heme oxygenase-1 protects against excessive inflammatory responses in human monocytes. J. Immunol. 181:6730–7.
-
(2008)
J. Immunol
, vol.181
, pp. 6730-6737
-
-
Rushworth, S.A.1
Macewan, D.J.2
O’Connell, M.A.3
-
34
-
-
0033617522
-
Notch signaling: Cell fate control and signal integration in development
-
Artavanis-Tsakonas S, Rand MD, Lake RJ. (1999) Notch signaling: cell fate control and signal integration in development. Science. 284:770–6.
-
(1999)
Science
, vol.284
, pp. 770-776
-
-
Artavanis-Tsakonas, S.1
Rand, M.D.2
Lake, R.J.3
-
35
-
-
1842480002
-
Expression of Notch-1 and its ligand Jagged-1 in rat liver during liver regeneration
-
Kohler C, et al. (2004) Expression of Notch-1 and its ligand Jagged-1 in rat liver during liver regeneration. Hepatology. 39:1056–65.
-
(2004)
Hepatology
, vol.39
, pp. 1056-1065
-
-
Kohler, C.1
-
36
-
-
80052026460
-
Canonical notch pathway protects hepatocytes from ischemia/reperfusion injury in mice by repressing reactive oxygen species production through JAK2/STAT3 signaling
-
Yu HC, et al. (2011) Canonical notch pathway protects hepatocytes from ischemia/reperfusion injury in mice by repressing reactive oxygen species production through JAK2/STAT3 signaling. Hepatology. 54:979–88.
-
(2011)
Hepatology
, vol.54
, pp. 979-988
-
-
Yu, H.C.1
-
37
-
-
69249156978
-
The notch target gene HES1 regulates cell cycle inhibitor expression in the developing pituitary
-
Monahan P, Rybak S, Raetzman LT. (2009) The notch target gene HES1 regulates cell cycle inhibitor expression in the developing pituitary. Endocrinology. 150:4386–94.
-
(2009)
Endocrinology
, vol.150
, pp. 4386-4394
-
-
Monahan, P.1
Rybak, S.2
Raetzman, L.T.3
-
38
-
-
33646411489
-
Notch signaling via Hes1 transcription factor maintains survival of melanoblasts and melanocyte stem cells
-
Moriyama M, et al. (2006) Notch signaling via Hes1 transcription factor maintains survival of melanoblasts and melanocyte stem cells. J. Cell Biol. 173:333–9.
-
(2006)
J. Cell Biol
, vol.173
, pp. 333-339
-
-
Moriyama, M.1
-
39
-
-
0033136717
-
Deficient T cell fate specification in mice with an induced inactivation of Notch1
-
Radtke F, et al. (1999) Deficient T cell fate specification in mice with an induced inactivation of Notch1. Immunity. 10:547–58.
-
(1999)
Immunity
, vol.10
, pp. 547-558
-
-
Radtke, F.1
-
40
-
-
0030708925
-
Mediation of NGF signaling by post-translational inhibition of HES-1, a basic helix-loop-helix repressor of neuronal differentiation
-
Strom A, Castella P, Rockwood J, Wagner J, Caudy M. (1997) Mediation of NGF signaling by post-translational inhibition of HES-1, a basic helix-loop-helix repressor of neuronal differentiation. Genes Dev. 11:3168–81.
-
(1997)
Genes Dev
, vol.11
, pp. 3168-3181
-
-
Strom, A.1
Castella, P.2
Rockwood, J.3
Wagner, J.4
Caudy, M.5
-
41
-
-
0037218811
-
Growth suppression of pre- T acute lymphoblastic leukemia cells by inhibition of notch signaling
-
Weng AP, et al. (2003) Growth suppression of pre- T acute lymphoblastic leukemia cells by inhibition of notch signaling. Mol. Cell. Biol. 23:655–64.
-
(2003)
Mol. Cell. Biol
, vol.23
, pp. 655-664
-
-
Weng, A.P.1
-
42
-
-
18144386919
-
Hes1 directly controls cell proliferation through the transcriptional repression of p27Kip1
-
Murata K, et al. (2005) Hes1 directly controls cell proliferation through the transcriptional repression of p27Kip1. Mol. Cell. Biol. 25:4262–71.
-
(2005)
Mol. Cell. Biol
, vol.25
, pp. 4262-4271
-
-
Murata, K.1
-
43
-
-
0030702123
-
Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery
-
Datta SR, et al. (1997) Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery. Cell. 91:231–41.
-
(1997)
Cell
, vol.91
, pp. 231-241
-
-
Datta, S.R.1
-
45
-
-
0036185848
-
The protein kinase B/Akt signalling pathway in human malignancy
-
Nicholson KM, Anderson NG. (2002) The protein kinase B/Akt signalling pathway in human malignancy. Cell Signal. 14:381–95.
-
(2002)
Cell Signal
, vol.14
, pp. 381-395
-
-
Nicholson, K.M.1
Erson, N.G.2
-
46
-
-
0035133227
-
Akt phosphorylates and negatively regulates apoptosis signal-regulating kinase 1
-
Kim AH, Khursigara G, Sun X, Franke TF, Chao MV. (2001) Akt phosphorylates and negatively regulates apoptosis signal-regulating kinase 1. Mol. Cell. Biol. 21:893–901.
-
(2001)
Mol. Cell. Biol
, vol.21
, pp. 893-901
-
-
Kim, A.H.1
Khursigara, G.2
Sun, X.3
Franke, T.F.4
Chao, M.V.5
-
47
-
-
34248172324
-
Altered macrophage differentiation and immune dysfunction in tumor development
-
Sica A, Bronte V. (2007) Altered macrophage differentiation and immune dysfunction in tumor development. J. Clin. Invest. 117:1155–66.
-
(2007)
J. Clin. Invest
, vol.117
, pp. 1155-1166
-
-
Sica, A.1
Bronte, V.2
-
48
-
-
2942709503
-
Hes binding to STAT3 mediates crosstalk between Notch and JAK-STAT signalling
-
Kamakura S, et al. (2004) Hes binding to STAT3 mediates crosstalk between Notch and JAK-STAT signalling. Nat. Cell Biol. 6:547–54.
-
(2004)
Nat. Cell Biol
, vol.6
, pp. 547-554
-
-
Kamakura, S.1
|