Antioxidants and phase 2 enzymes in macrophages: Regulation by Nrf2 signaling and protection against oxidative and electrophilic stress

Experimental Biology and Medicine

Volumn 233, Issue 4, 2008, Pages 463-474

  Zhu, Hong ^a   Jia, Zhenquan ^a   Zhang, Li ^b   Yamamoto, Masayuki ^c   Misra, Hara P ^a,d   Trush, Michael A ^e   Li, Yunbo ^a,d  

^a EDWARD VIA COLLEGE OF OSTEOPATHIC MEDICINE   (United States)

^b OHIO STATE UNIVERSITY   (United States)

^c UNIVERSITY OF TSUKUBA   (Japan)

^d VIRGINIA MARYLAND REGIONAL COLLEGE OF VETERINARY MEDICINE   (United States)

^e JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Cytotoxicity; Electrophiles; Macrophages; Nrf2; Oxidants; Phase 2 enzymes

Indexed keywords

1,2 DITHIOLE 3 THIONE DERIVATIVE; ACROLEIN; ANTIOXIDANT; CADMIUM; CATALASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; GLUTATHIONE TRANSFERASE; NITROGEN 13; OXIDOREDUCTASE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; TRANSCRIPTION FACTOR NRF2;

ANIMAL CELL; ARTICLE; CELL DAMAGE; CELL PROTECTION; ELECTROPHILIC STRESS; INCUBATION TIME; MACROPHAGE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; WILD TYPE;

ACROLEIN; ANIMALS; ANTIOXIDANTS; CADMIUM; CATALASE; CELLS, CULTURED; ENZYME INDUCTION; FEMALE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE TRANSFERASE; HYDROGEN PEROXIDE; MACROPHAGES; MICE; MICE, KNOCKOUT; NADPH DEHYDROGENASE; NF-E2-RELATED FACTOR 2; OXIDANTS; OXIDATIVE STRESS; PEROXYNITROUS ACID; SIGNAL TRANSDUCTION; SUPEROXIDE DISMUTASE; THIONES;

MUS;

EID: 41549129055     PISSN: 15353702     EISSN: 15353699     Source Type: Journal    
DOI: 10.3181/0711-RM-304     Document Type: Article

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