RNF4-Dependent Oncogene Activation by Protein Stabilization

Cell Reports

Volumn 16, Issue 12, 2016, Pages 3388-3400

  Abed, Mona ^a,g   Heuberger, Julian ^c   Novak, Rostislav ^a,b   Zohar, Yaniv ^a,b   Beltran Lopez, Angela P ^d   Trausch Azar, Julie S ^e   Ilagan, Ma Xenia G ^e   Benhamou, David ^a   Dittmar, Gunnar ^c   Kopan, Raphael ^f   Birchmeier, Walter ^c   Schwartz, Alan L ^e   Orian, Amir ^a  

^a TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

^b RAMBAM MEDICAL CENTER   (Israel)

^c MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^d UNIVERSIDAD NACIONAL DE COLOMBIA   (Colombia)

^e WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^g GENENTECH INC   (United States)

Author keywords

gene regulation; oncogenes; STUbL; SUMO; ubiquitin

Indexed keywords

BETA CATENIN; MESSENGER RNA; MYC PROTEIN; NOTCH RECEPTOR; ONCOPROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; POLYUBIQUITIN; PROTEIN C JUN; RING FINGER PROTEIN; RING FINGER PROTEIN 4; SUMO PROTEIN; TRANSCRIPTION FACTOR; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG; WNT PROTEIN; NUCLEAR PROTEIN; RNF4 PROTEIN, HUMAN;

ARTICLE; BREAST CANCER; CANCER CELL; CANCER SURVIVAL; CELL SURVIVAL; CHROMATIN; COLON ADENOCARCINOMA; CONTROLLED STUDY; DISEASE ASSOCIATION; ENZYME PHOSPHORYLATION; ENZYME SUBSTRATE; ENZYME SUBSTRATE COMPLEX; EPITHELIUM TUMOR; GENE ACTIVATION; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; HUMAN TISSUE; MAJOR CLINICAL STUDY; MOLECULAR DOCKING; ONCOGENE; POSITIVE FEEDBACK; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN STABILITY; SUMOYLATION; TRANSCRIPTION REGULATION; TUMOR GROWTH; UBIQUITINATION; UPREGULATION; WNT SIGNALING PATHWAY; METABOLISM; PHYSIOLOGY;

HUMANS; NUCLEAR PROTEINS; ONCOGENES; PROTEIN STABILITY; TRANSCRIPTION FACTORS; UBIQUITINATION;

EID: 84991687529     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2016.08.024     Document Type: Article

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