Shp2/MAPK signaling controls goblet/paneth cell fate decisions in the intestine

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 9, 2014, Pages 3472-3477

  Heuberger, Julian ^a   Kosel, Frauke ^a   Qi, Jingjing ^a   Grossmann, Katja S ^a,b   Rajewsky, Klaus ^a   Birchmeier, Walter ^a  

^a MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^b Deutsche Forschungsgemeinschaft   (Germany)

Author keywords

Crypt; Mek1DD; PTPN11; RTK; TCF7L2

Indexed keywords

BETA CATENIN; LEUCINE RICH REPEAT KINASE 2; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; PROTEIN TYROSINE PHOSPHATASE SHP 2; T CELL FACTOR PROTEIN; TRANSCRIPTION FACTOR TCF4; UNCLASSIFIED DRUG; WNT1 PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; CELL FATE; CELL MATURATION; CONTROLLED STUDY; CYTOPLASM; ENZYME ACTIVATION; GENE MUTATION; GOBLET CELL; INTESTINE CRYPT; INTESTINE EPITHELIUM; MOUSE; NONHUMAN; PANETH CELL; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SECRETORY CELL; SIGNAL TRANSDUCTION; STEM CELL; STEM CELL NICHE;

CRYPT; MEK1DD; PTPN11; RTK; TCF7L2;

ANIMALS; BETA CATENIN; BLOTTING, WESTERN; CELL DIFFERENTIATION; GOBLET CELLS; HT29 CELLS; HUMANS; IMMUNOPRECIPITATION; INTESTINAL MUCOSA; MICE; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; ORGAN CULTURE TECHNIQUES; PANETH CELLS; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 11; STEM CELLS; WNT SIGNALING PATHWAY;

EID: 84895803050     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1309342111     Document Type: Article

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