RNF4 interacts with both SUMO and nucleosomes to promote the DNA damage response

EMBO Reports

Volumn 15, Issue 5, 2014, Pages 601-608

  Groocock, Lynda M ^a   Nie, Minghua ^a   Prudden, John ^a   Moiani, Davide ^a   Wang, Tao ^b   Cheltsov, Anton ^c   Rambo, Robert P ^d   Arvai, Andrew S ^a   Hitomi, Chiharu ^a   Tainer, John A ^a,d   Luger, Karolin ^b   Perry, J Jefferson P ^a,e   Lazzerini Denchi, Eros ^a   Boddy, Michael N ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b Department of Environmental and Radiological Health Sciences   (United States)

^c Q MOL LLC   (United States)

^d LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^e AMRITA UNIVERSITY   (India)

Author keywords

RNF4; small ubiquitin like modifier; SUMO targeted E3 ubiquitin ligase (STUbL); telomere; ubiquitin

Indexed keywords

DOUBLE STRANDED DNA; RNF 4 PROTEIN; SUMO PROTEIN; TELOMERIC REPEAT BINDING FACTOR 2; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG; AFIMOXIFENE; DNA BINDING PROTEIN; NONHISTONE PROTEIN; NUCLEAR PROTEIN; NUCLEOSOME; RNF4 PROTEIN, MOUSE; TAMOXIFEN; TRANSCRIPTION FACTOR; TRF2 PROTEIN, MOUSE; TRP53BP1 PROTEIN, MOUSE; UBIQUITIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DNA BINDING MOTIF; DNA DAMAGE; DNA REPAIR; EMBRYO; GENE TARGETING; HISTONE UBIQUITINATION; HUMAN; MOUSE; NONHUMAN; NUCLEOSOME; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; RING FINGER MOTIF; SIGNAL TRANSDUCTION; TELOMERE; ANALOGS AND DERIVATIVES; ANIMAL; CELL LINE; DRUG EFFECTS; GENE INACTIVATION; GENETICS; METABOLISM; PROTEIN MOTIF; PROTEIN PROCESSING; PROTEIN TERTIARY STRUCTURE; UBIQUITINATION; ULTRASTRUCTURE; X RAY CRYSTALLOGRAPHY;

AMINO ACID MOTIFS; ANIMALS; CELL LINE; CHROMOSOMAL PROTEINS, NON-HISTONE; CRYSTALLOGRAPHY, X-RAY; DNA DAMAGE; DNA REPAIR; DNA-BINDING PROTEINS; GENE KNOCKOUT TECHNIQUES; MICE; NUCLEAR PROTEINS; NUCLEOSOMES; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STRUCTURE, TERTIARY; SMALL UBIQUITIN-RELATED MODIFIER PROTEINS; TAMOXIFEN; TELOMERE; TELOMERIC REPEAT BINDING PROTEIN 2; TRANSCRIPTION FACTORS; UBIQUITIN; UBIQUITINATION;

EID: 84899854860     PISSN: 1469221X     EISSN: 14693178     Source Type: Journal    
DOI: 10.1002/embr.201338369     Document Type: Article

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