Ring Finger Protein 14 is a new regulator of TCF/β-catenin-mediated transcription and colon cancer cell survival

EMBO Reports

Volumn 14, Issue 4, 2013, Pages 347-355

  Wu, Beibei ^a   Piloto, Sarah ^b,c   Zeng, Weihua ^b   Hoverter, Nate P ^a   Schilling, Thomas F ^b   Waterman, Marian L ^a  

^a School of Medicine   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c BURNHAM INSTITUTE   (United States)

Author keywords

catenin; colon cancer; TCF transcription factors; Wnt

Indexed keywords

CYCLIN D1; GLUTATHIONE TRANSFERASE; RING FINGER PROTEIN; RING FINGER PROTEIN 14; T CELL FACTOR PROTEIN; UNCLASSIFIED DRUG; WNT PROTEIN;

ARTICLE; CELL SURVIVAL; COLON CANCER; CONTROLLED STUDY; GENE CONTROL; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IN VIVO STUDY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION; UPREGULATION;

ANIMALS; BETA CATENIN; CELL SURVIVAL; COLONIC NEOPLASMS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE KNOCKDOWN TECHNIQUES; HCT116 CELLS; HEK293 CELLS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; RNA, SMALL INTERFERING; TCF TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; UP-REGULATION; WNT SIGNALING PATHWAY; ZEBRAFISH;

DANIO RERIO;

EID: 84876491434     PISSN: 1469221X     EISSN: 14693178     Source Type: Journal    
DOI: 10.1038/embor.2013.19     Document Type: Article

References (22)

1. Bienz M, Clevers H (2000) Linking colorectal cancer to Wnt signaling. Cell 103: 311-320
2. Mosimann C, Hausmann G, Basler K (2009) b-catenin hits chromatin: regulation of Wnt target gene activation. Nat Rev Mol Cell Biol 10: 276-286
3. Cadigan KM, Waterman ML (2012) TCF/LEFs and Wnt signaling in the nucleus. Cold Spring Harb Perspect Biol 4: a007906
4. Love JJ, Li X, Case DA, Giese K, Grosschedl R, Wright PE (1995) Structural basis for DNA bending by the architectural transcription factor LEF-1. Nature 376: 791-795
5. Kang HY, Yeh S, Fujimoto N, Chang C (1999) Cloning and characterization of human prostate coactivator ARA54, a novel protein that associates with the androgen receptor. J Biol Chem 274: 8570-8576 (Pubitemid 29164648)
6. Ito K et al (2001) N-Terminally extended human ubiquitin-conjugating enzymes (E2s) mediate the ubiquitination of RING-finger proteins, ARA54 and RNF8. Eur J Biochem 268: 2725-2732 (Pubitemid 32853012)
7. Miyamoto H et al (2001) A dominant-negative mutant of androgen receptor coregulator ARA54 inhibits androgen receptor-mediated prostate cancer growth. J Biol Chem 277: 4609-4617
8. Dorsky RI, Sheldahl LC, Moon RT (2002) A transgenic Lef1/b-catenin- dependent reporter is expressed in spatially restricted domains throughout zebrafish development. Dev Biol 241: 229-237 (Pubitemid 34098688)
9. Takahashi M, Nakamura Y, Obama K, Furukawa Y (2005) Identification of SP5 as a downstream gene of the b-catenin/Tcf pathway and its enhanced expression in human colon cancer. Int J Oncol 27: 1483-1487
10. Hovanes K et al (2001) b-catenin-sensitive isoforms of lymphoid enhancer factor-1 are selectively expressed in colon cancer. Nat Genet 28: 53-57 (Pubitemid 32405817)
11. Kikuchi H et al (2007) ARA54 is involved in transcriptional regulation of the cyclin D1 gene in human cancer cells. Carcinogenesis 28: 1752-1758 (Pubitemid 47289038)
12. Sansom OJ et al (2005) Cyclin D1 is not an immediate target of b-catenin following Apc loss in the intestine. J Biol Chem 280: 28463-28467 (Pubitemid 41105745)
13. Spaulding C et al (2007) Notch1 coopts lymphoid enhancer factor 1 for survival of murine T-cell lymphomas. Blood 110: 2650-2658 (Pubitemid 47523189)
14. Sierra J, Yoshida T, Joazeiro CA, Jones KA (2006) The APC tumor suppressor counteracts b-catenin activation and H3K4 methylation at Wnt target genes. Genes Dev 20: 586-600 (Pubitemid 43345324)
15. Mohan M et al (2010) Linking H3K79 trimethylation to Wnt signaling through a novel Dot1-containing complex (DotCom). Genes Dev 24: 574-589
16. Arce L, Pate KT, Waterman ML (2009) Groucho binds two conserved regions of LEF-1for HDAC-dependent repression. BMC Cancer 9: 159
17. Tran H, Hamada F, Schwarz-Romond T, Bienz M (2008) Trabid, a new positive regulator of Wnt-induced transcription with preference for binding and cleaving K63-linked ubiquitin chains. Genes Dev 22: 528-542 (Pubitemid 351272759)
18. Li J, Wang C-Y (2008) TBL1-TBLR1 and b-catenin recruit each other to Wnt target-gene promoter for transcription activation and oncogenesis. Nat Cell Biol 10: 160-169 (Pubitemid 351194045)
19. Hanson AJ, Wallace HA, Freeman TJ, Beauchamp RD, Lee LA, Lee E (2012) XIAP monoubiquitylates Groucho/TLE to promote canonical Wnt signaling. Mol Cell 45: 619-628
20. Thisse C, Thisse B, Schilling TF, Postlethwait JH (1993) Structure of the zebrafish snail1 gene and its expression in wild-type, spadetail and no tail mutant embryos. Development 119: 1205-1215
21. Skehan P et al (1990) New colorimetric cytotoxicity assay for anticancer-drug screening. J Natl Cancer Inst 82: 1107-1112 (Pubitemid 20213250)
22. Zeng W et al (2009) Specific loss of histone H3 lysine 9 trimethylation and HP1g/cohesin binding at D4Z4 repeats is associated with facioscapulohumeral dystrophy (FSHD). PLoS Genet 5: e10000559