c-Myc is targeted to the proteasome for degradation in a SUMOylation-dependent manner, regulated by PIAS1, SENP7 and RNF4

Cell Cycle

Volumn 14, Issue 12, 2015, Pages 1859-1872

  González Prieto, Román ^a   Cuijpers, Sabine A G ^a   Kumar, Ramesh ^a   Hendriks, Ivo A ^a   Vertegaal, Alfred C O ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

C Myc; PIAS1; Proteasome; RNF4; SENP7; SUMO

Indexed keywords

LIGASE; MYC PROTEIN; PROTEASOME; PROTEIN INHIBITOR OF ACTIVATED STAT; PROTEIN INHIBITOR OF ACTIVATED STAT 1; RNF4 PROTEIN; SENP7 PROTEIN; SUMO 1 PROTEIN; SUMO 2 PROTEIN; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG; LYSINE; MYC PROTEIN, HUMAN; NUCLEAR PROTEIN; PIAS1 PROTEIN, HUMAN; PROTEINASE; RNF4 PROTEIN, HUMAN; SENP7 PROTEIN, HUMAN; SUMO PROTEIN; TRANSCRIPTION FACTOR;

ARTICLE; CONTROLLED STUDY; DEPOLYMERIZATION; GENE SILENCING; HUMAN; HUMAN CELL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; RING FINGER MOTIF; SUMOYLATION; TRANSLATION REGULATION; U2OS CELL LINE; CELL NUCLEUS; CHEMISTRY; CYTOPLASM; GENE EXPRESSION REGULATION; GENETICS; HELA CELL LINE; MASS SPECTROMETRY; METABOLISM; PHOSPHORYLATION; PROTEIN MOTIF; PROTEIN TRANSPORT; TUMOR CELL LINE; UBIQUITINATION;

AMINO ACID MOTIFS; CELL LINE, TUMOR; CELL NUCLEUS; CYTOPLASM; ENDOPEPTIDASES; GENE EXPRESSION REGULATION, NEOPLASTIC; HELA CELLS; HUMANS; LYSINE; MASS SPECTROMETRY; NUCLEAR PROTEINS; PHOSPHORYLATION; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN INHIBITORS OF ACTIVATED STAT; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN TRANSPORT; PROTEOLYSIS; PROTO-ONCOGENE PROTEINS C-MYC; SMALL UBIQUITIN-RELATED MODIFIER PROTEINS; SUMOYLATION; TRANSCRIPTION FACTORS; UBIQUITINATION;

EID: 84943811024     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.1080/15384101.2015.1040965     Document Type: Article

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