B7-H1 shapes t-cell-mediated brain endothelial cell dysfunction and regional encephalitogenicity in spontaneous CNS autoimmunity

Proceedings of the National Academy of Sciences of the United States of America

Volumn 113, Issue 41, 2016, Pages E6182-E6191

  Klotz, Luisa ^a   Kuzmanov, Ivan ^a   Hucke, Stephanie ^a   Gross, Catharina C ^a   Posevitz, Vilmos ^a,e   Dreykluft, Angela ^b,f   Schulte Mecklenbeck, Andreas ^a   Janoschka, Claudia ^a   Lindner, Maren ^a   Herold, Martin ^a   Schwab, Nicholas ^a   Ludwig Portugall, Isis ^c   Kurts, Christian ^c   Meuth, Sven G ^a   Kuhlmann, Tanja ^d   Wiendl, Heinz ^a  

^a UNIVERSITY HOSPITAL MÜNSTER   (Germany)

^b UNIVERSITY HOSPITAL WÜRZBURG   (Germany)

^c UNIVERSITY OF BONN   (Germany)

^d UNIVERSITY OF MÜNSTER   (Germany)

^e Ganymed Pharmaceuticals AG   (Germany)

^f SOMNOmedics GmbH   (Germany)

Author keywords

Blood brain barrier; Cns lesion distribution; Multiple sclerosis; Neuroinflammation; Spontaneous eae

Indexed keywords

GAMMA INTERFERON; GRANZYME B; PROGRAMMED DEATH 1 LIGAND 1;

ANIMAL CELL; ANTIGEN PRESENTING CELL; ARTICLE; AUTOIMMUNITY; BLOOD BRAIN BARRIER; CAPILLARY ENDOTHELIAL CELL; CELL CONTACT; CONTROLLED STUDY; DISEASE COURSE; DISEASE SEVERITY; ENDOTHELIAL DYSFUNCTION; IMMUNOSURVEILLANCE; MORBIDITY; MOUSE; MULTIPLE SCLEROSIS; NONHUMAN; OLIGODENDROGLIA; PATHOGENESIS; PHENOTYPIC VARIATION; PRIORITY JOURNAL; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; ANIMAL; BRAIN; ENDOTHELIUM CELL; EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS; GENE KNOCKOUT; GENETIC PREDISPOSITION; GENETICS; IMMUNOLOGY; METABOLISM; MORTALITY; PATHOLOGY; PERMEABILITY; SEVERITY OF ILLNESS INDEX; T LYMPHOCYTE SUBPOPULATION; TRANSGENIC MOUSE;

ANIMALS; AUTOIMMUNITY; B7-H1 ANTIGEN; BLOOD-BRAIN BARRIER; BRAIN; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; ENDOTHELIAL CELLS; GENE KNOCKOUT TECHNIQUES; GENETIC PREDISPOSITION TO DISEASE; MICE; MICE, TRANSGENIC; MORTALITY; PERMEABILITY; SEVERITY OF ILLNESS INDEX; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES;

EID: 84991442387     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1601350113     Document Type: Article

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