Polarized granzyme release is required for antigen-driven transendothelial migration of human effector memory CD4 T cells

Journal of Immunology

Volumn 193, Issue 12, 2014, Pages 5809-5815

  Manes, Thomas D ^a   Pober, Jordan S ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DYNEIN ADENOSINE TRIPHOSPHATASE; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GRANZYME; GRANZYME B; JASPAMIDE; MYOSIN IIA; PERFORIN; STROMAL CELL DERIVED FACTOR 1; ANTIGEN; CHEMOKINE; LYMPHOCYTE ANTIGEN RECEPTOR;

ACTIN POLYMERIZATION; ARTICLE; CD4+ T LYMPHOCYTE; CELL NUCLEUS; CELL POLARITY; CHEMOTAXIS; CONTROLLED STUDY; DEPOLYMERIZATION; ENDOTHELIUM; ENZYME ACTIVITY; ENZYME RELEASE; EXOCYTOSIS; HUMAN; HUMAN CELL; LEUKOCYTE; MICROTUBULE ORGANIZING CENTER; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; SYNAPSE; TRANSENDOTHELIAL AND TRANSEPITHELIAL MIGRATION; CELL GRANULE; IMMUNOLOGY; METABOLISM; MICROTUBULE; PROTEIN TRANSPORT;

ANTIGENS; CD4-POSITIVE T-LYMPHOCYTES; CHEMOKINES; CYTOPLASMIC GRANULES; EXOCYTOSIS; GRANZYMES; HUMANS; MICROTUBULES; PROTEIN TRANSPORT; RECEPTORS, ANTIGEN, T-CELL; TRANSENDOTHELIAL AND TRANSEPITHELIAL MIGRATION;

EID: 84916919274     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1401665     Document Type: Article

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