Granzyme B induces endothelial cell apoptosis and contributes to the development of transplant vascular disease

American Journal of Transplantation

Volumn 5, Issue 3, 2005, Pages 494-499

  Choy, Jonathan C ^a   Cruz, Rani P ^a   Kerjner, Alexandra ^a   Geisbrecht, Jennette ^b   Sawchuk, Tracy ^c   Fraser, Stephanie A ^d   Hudig, Dorothy ^d   Bleackley, R Chris ^c   Jirik, Frank R ^b   McManus, Bruce M ^a   Granville, David J ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b UNIVERSITY OF CALGARY   (Canada)

^c UNIVERSITY OF ALBERTA   (Canada)

^d UNIVERSITY OF NEVADA SCHOOL OF MEDICINE   (United States)

Author keywords

Apoptosis; Endothelial cell; Granzyme B; T cell; Transplant coronary artery disease; Transplant vascular disease; Vasculopathy

Indexed keywords

GRANZYME B; PERFORIN;

ALLOGRAFT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTERY DIAMETER; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; ENDOTHELIUM CELL; HEART TRANSPLANTATION; IMMUNE RESPONSE; KNOCKOUT MOUSE; MALE; MOLECULAR MECHANICS; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; TRANSPLANT VASCULAR DISEASE; VASCULAR DISEASE; VASCULITIS;

ANIMALS; APOPTOSIS; ARTERIES; ENDOTHELIAL CELLS; GRAFT SURVIVAL; GRANZYMES; HUMANS; MEMBRANE GLYCOPROTEINS; MICE; PORE FORMING CYTOTOXIC PROTEINS; SERINE ENDOPEPTIDASES; TRANSPLANTATION, HOMOLOGOUS;

EID: 20044372704     PISSN: 16006135     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-6143.2004.00710.x     Document Type: Article

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