Cytotoxic and proinflammatory CD8+ T lymphocytes promote development of vulnerable atherosclerotic plaques in ApoE-deficient mice

Circulation

Volumn 127, Issue 9, 2013, Pages 1028-1039

  Kyaw, Tin ^a,b   Winship, Amy ^a   Tay, Christopher ^a,b   Kanellakis, Peter ^a   Hosseini, Hamid ^a,b   Cao, Anh ^b   Li, Priscilla ^a   Tipping, Peter ^b,c   Bobik, Alex ^a   Toh, Ban Hock ^b  

^a BAKER IDI HEART AND DIABETES INSTITUTE   (Australia)

^b MONASH UNIVERSITY   (Australia)

^c HUDSON INSTITUTE OF MEDICAL RESEARCH   (Australia)

Author keywords

CD8+ T cells; granzyme B; perforin; vulnerable atherosclerotic plaque

Indexed keywords

APOLIPOPROTEIN E; GRANZYME B; INTERLEUKIN 1BETA; PERFORIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; CD8+ T LYMPHOCYTE; CELL ISOLATION; CELL SELECTION; CELLULAR IMMUNITY; CONTROLLED STUDY; ENDOTHELIUM CELL; FEMALE; IMMUNE RESPONSE; IMMUNOCOMPETENT CELL; IMMUNOHISTOCHEMISTRY; LIPID DIET; MACROPHAGE; MOUSE; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; WILD TYPE;

ANIMALS; APOLIPOPROTEINS E; CD8-POSITIVE T-LYMPHOCYTES; DIET, HIGH-FAT; INFLAMMATION; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PLAQUE, ATHEROSCLEROTIC; T-LYMPHOCYTES, CYTOTOXIC;

EID: 84874650489     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.112.001347     Document Type: Article

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