Antibody-drug conjugates: recent advances in conjugation and linker chemistries

Protein and Cell

Volumn 9, Issue 1, 2018, Pages 33-46

  Tsuchikama, Kyoji ^a   An, Zhiqiang ^a  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

antibody drug conjugates; cancer; chemotherapy; conjugation; linker; site specific conjugation

Indexed keywords

ANTIBODY DRUG CONJUGATE; ANTIGEN; CATHEPSIN B; CYSTEINE; HYDRAZONE DERIVATIVE; MACROGOL; SORTASE; TUMOR ANTIGEN; VANDETANIB; AMINO ACID; ANTIBODY CONJUGATE; MONOCLONAL ANTIBODY;

AMINO ACID METABOLISM; BLOOD FLOW; CANCER CHEMOTHERAPY; CYTOTOXICITY; DRUG CONJUGATION; DRUG DELIVERY SYSTEM; ENDOCYTOSIS; ENZYME ACTIVITY; GENETIC ENGINEERING; HUMAN; IMMUNOGENICITY; MICROTUBULE; PRIORITY JOURNAL; REVIEW; ANIMAL; CHEMISTRY; METABOLISM;

AMINO ACIDS; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS; GENETIC ENGINEERING; HUMANS; IMMUNOCONJUGATES;

EID: 84991081605     PISSN: 1674800X     EISSN: 16748018     Source Type: Journal    
DOI: 10.1007/s13238-016-0323-0     Document Type: Review

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