Site-specific and stoichiometric modification of antibodies by bacterial transglutaminase

Angewandte Chemie - International Edition

Volumn 49, Issue 51, 2010, Pages 9995-9997

  Jeger, Simone ^a   Zimmermann, Kurt ^b   Blanc, Alain ^b   Grünberg, Jürgen ^b   Honer, Michael ^a   Hunziker, Peter ^a   Struthers, Harriet ^a   Schibli, Roger ^a  

^a ETH ZURICH   (Switzerland)

^b ETH Zurich   (Switzerland)

Author keywords

bacterial transglutaminase; enzymes; protein labeling; radioimmunoconjugates

Indexed keywords

CHEMICALLY MODIFIED; IN-VIVO; PHARMACOLOGICAL PROFILES; PROTEIN LABELING; RADIOIMMUNOCONJUGATES; SIDE CHAINS; SITE-SPECIFIC; SITE-SPECIFIC MODIFICATIONS; TRANSGLUTAMINASES;

AMINO ACIDS; ANTIBODIES; CATALYSTS; ENZYMES; STOICHIOMETRY;

BACTERIOLOGY;

ANTIBODY CONJUGATE; BACTERIAL PROTEIN; CANCER ANTIBODY; GLUTAMINE; LYSINE; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE;

ANIMAL; ARTICLE; METABOLISM; MOUSE; XENOGRAFT;

ANIMALS; ANTIBODIES, NEOPLASM; BACTERIAL PROTEINS; GLUTAMINE; IMMUNOCONJUGATES; LYSINE; MICE; TRANSGLUTAMINASES; TRANSPLANTATION, HETEROLOGOUS;

EID: 78650297318     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201004243     Document Type: Article

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