Sortase-mediated modification of aDEC205 affords optimization of antigen presentation and immunization against a set of viral epitopes

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 4, 2013, Pages 1428-1433

  Swee, Lee Kim ^a   Guimaraes, Carla P ^a   Sehrawat, Sharvan ^a   Spooner, Eric ^a   Barrasa, M Inmaculada ^a   Ploegh, Hidde L ^a  

^a WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD40 ANTIGEN; EPITOPE; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY ALPHA DEC205; POLYINOSINIC POLYCYTIDYLIC ACID; PROTEASOME; SORTASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN PRESENTATION; ARTICLE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; CROSS PRESENTATION; DENDRITIC CELL; GAMMAHERPESVIRINAE; IMMUNE RESPONSE; IMMUNIZATION; IMMUNOLOGICAL TOLERANCE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ENGINEERING; VIRUS LOAD;

AMINO ACID SEQUENCE; AMINOACYLTRANSFERASES; ANIMALS; ANTIGEN PRESENTATION; ANTIGENS, CD; ANTIGENS, VIRAL; BACTERIAL PROTEINS; CD8-POSITIVE T-LYMPHOCYTES; CYSTEINE ENDOPEPTIDASES; EPITOPES, T-LYMPHOCYTE; HERPESVIRIDAE INFECTIONS; HISTOCOMPATIBILITY ANTIGENS CLASS I; IMMUNIZATION; IMMUNOCONJUGATES; LECTINS, C-TYPE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN ENGINEERING; RECEPTORS, CELL SURFACE; RHADINOVIRUS; TUMOR VIRUS INFECTIONS; VACCINES, SUBUNIT; VIRAL VACCINES;

ANIMALIA; HERPESVIRIDAE;

EID: 84872871265     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1214994110     Document Type: Article

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