-
1
-
-
84867179824
-
The molecular basis of T cell acute lymphoblastic leukemia
-
Van Vlierberghe P, Ferrando A. The molecular basis of T cell acute lymphoblastic leukemia. J Clin Invest 2012; 122: 3398-3406.
-
(2012)
J Clin Invest
, vol.122
, pp. 3398-3406
-
-
Van Vlierberghe, P.1
Ferrando, A.2
-
2
-
-
30444437486
-
Treatment of acute lymphoblastic leukemia
-
Pui CH, Evans WE. Treatment of acute lymphoblastic leukemia. N Engl J Med 2006; 354: 166-178.
-
(2006)
N Engl J Med
, vol.354
, pp. 166-178
-
-
Pui, C.H.1
Evans, W.E.2
-
3
-
-
5044225888
-
Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia
-
Weng AP, Ferrando AA, Lee W, Morris JPT, Silverman LB, Sanchez-Irizarry C, et al. Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia. Science 2004; 306: 269-271.
-
(2004)
Science
, vol.306
, pp. 269-271
-
-
Weng, A.P.1
Ferrando, A.A.2
Lee, W.3
Morris, J.P.T.4
Silverman, L.B.5
Sanchez-Irizarry, C.6
-
4
-
-
34547780475
-
FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to gammasecretase inhibitors
-
O'Neil J, Grim J, Strack P, Rao S, Tibbitts D, Winter C, et al. FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to gammasecretase inhibitors. J Exp Med 2007; 204: 1813-1824.
-
(2007)
J Exp Med
, vol.204
, pp. 1813-1824
-
-
O'Neil, J.1
Grim, J.2
Strack, P.3
Rao, S.4
Tibbitts, D.5
Winter, C.6
-
5
-
-
34547820257
-
The SCFFBW7 ubiquitin ligase complex as a tumor suppressor in T cell leukemia
-
Thompson BJ, Buonamici S, Sulis ML, Palomero T, Vilimas T, Basso G, et al. The SCFFBW7 ubiquitin ligase complex as a tumor suppressor in T cell leukemia. J Exp Med 2007; 204: 1825-1835.
-
(2007)
J Exp Med
, vol.204
, pp. 1825-1835
-
-
Thompson, B.J.1
Buonamici, S.2
Sulis, M.L.3
Palomero, T.4
Vilimas, T.5
Basso, G.6
-
6
-
-
79951516547
-
Molecular pathogenesis and targeted therapies for NOTCH1-induced T-cell acute lymphoblastic leukemia
-
Paganin M, Ferrando A. Molecular pathogenesis and targeted therapies for NOTCH1-induced T-cell acute lymphoblastic leukemia. Blood Rev 2011; 25: 83-90.
-
(2011)
Blood Rev
, vol.25
, pp. 83-90
-
-
Paganin, M.1
Ferrando, A.2
-
7
-
-
64249172203
-
The canonical Notch signaling pathway: Unfolding the activation mechanism
-
Kopan R, Ilagan MX. The canonical Notch signaling pathway: unfolding the activation mechanism. Cell 2009; 137: 216-233.
-
(2009)
Cell
, vol.137
, pp. 216-233
-
-
Kopan, R.1
Ilagan, M.X.2
-
8
-
-
77953916528
-
HSP90 at the hub of protein homeostasis: Emerging mechanistic insights
-
Taipale M, Jarosz DF, Lindquist S. HSP90 at the hub of protein homeostasis: emerging mechanistic insights. Nat Rev Mol Cell Biol 2010; 11: 515-528.
-
(2010)
Nat Rev Mol Cell Biol
, vol.11
, pp. 515-528
-
-
Taipale, M.1
Jarosz, D.F.2
Lindquist, S.3
-
9
-
-
78049421614
-
Notch dimerization is required for leukemogenesis and T-cell development
-
Liu H, Chi AW, Arnett KL, Chiang MY, Xu L, Shestova O, et al. Notch dimerization is required for leukemogenesis and T-cell development. Genes Dev 2010; 24: 2395-2407.
-
(2010)
Genes Dev
, vol.24
, pp. 2395-2407
-
-
Liu, H.1
Chi, A.W.2
Arnett, K.L.3
Chiang, M.Y.4
Xu, L.5
Shestova, O.6
-
10
-
-
33746546368
-
C-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma
-
Weng AP, Millholland JM, Yashiro-Ohtani Y, Arcangeli ML, Lau A, Wai C, et al. c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma. Genes Dev 2006; 20: 2096-2109.
-
(2006)
Genes Dev
, vol.20
, pp. 2096-2109
-
-
Weng, A.P.1
Millholland, J.M.2
Yashiro-Ohtani, Y.3
Arcangeli, M.L.4
Lau, A.5
Wai, C.6
-
11
-
-
0035146685
-
The co-chaperone CHIP regulates protein triage decisions mediated by heatshock proteins
-
Connell P, Ballinger CA, Jiang J, Wu Y, Thompson LJ, Hohfeld J, et al. The co-chaperone CHIP regulates protein triage decisions mediated by heatshock proteins. Nat Cell Biol 2001; 3: 93-96.
-
(2001)
Nat Cell Biol
, vol.3
, pp. 93-96
-
-
Connell, P.1
Ballinger, C.A.2
Jiang, J.3
Wu, Y.4
Thompson, L.J.5
Hohfeld, J.6
-
12
-
-
34547484864
-
Notch signaling induces SKP2 expression and promotes reduction of p27Kip1 in T-cell acute lymphoblastic leukemia cell lines
-
Dohda T, Maljukova A, Liu L, Heyman M, Grander D, Brodin D, et al. Notch signaling induces SKP2 expression and promotes reduction of p27Kip1 in T-cell acute lymphoblastic leukemia cell lines. Exp Cell Res 2007; 313: 3141-3152.
-
(2007)
Exp Cell Res
, vol.313
, pp. 3141-3152
-
-
Dohda, T.1
Maljukova, A.2
Liu, L.3
Heyman, M.4
Grander, D.5
Brodin, D.6
-
13
-
-
58549099738
-
ChIP-on-chip significance analysis reveals large-scale binding and regulation by human transcription factor oncogenes
-
Margolin AA, Palomero T, Sumazin P, Califano A, Ferrando AA, Stolovitzky G. ChIP-on-chip significance analysis reveals large-scale binding and regulation by human transcription factor oncogenes. Proc Natl Acad Sci USA 2009; 106: 244-249.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 244-249
-
-
Margolin, A.A.1
Palomero, T.2
Sumazin, P.3
Califano, A.4
Ferrando, A.A.5
Stolovitzky, G.6
-
14
-
-
80054834757
-
High-level IGF1R expression is required for leukemia-initiating cell activity in T-ALL and is supported by Notch signaling
-
Medyouf H, Gusscott S, Wang H, Tseng JC, Wai C, Nemirovsky O, et al. High-level IGF1R expression is required for leukemia-initiating cell activity in T-ALL and is supported by Notch signaling. J Exp Med 2011; 208: 1809-1822.
-
(2011)
J Exp Med
, vol.208
, pp. 1809-1822
-
-
Medyouf, H.1
Gusscott, S.2
Wang, H.3
Tseng, J.C.4
Wai, C.5
Nemirovsky, O.6
-
15
-
-
58149336788
-
Gamma-secretase inhibitors reverse glucocorticoid resistance in T cell acute lymphoblastic leukemia
-
Real PJ, Tosello V, Palomero T, Castillo M, Hernando E, de Stanchina E, et al. Gamma-secretase inhibitors reverse glucocorticoid resistance in T cell acute lymphoblastic leukemia. Nat Med 2009; 15: 50-58.
-
(2009)
Nat Med
, vol.15
, pp. 50-58
-
-
Real, P.J.1
Tosello, V.2
Palomero, T.3
Castillo, M.4
Hernando, E.5
De Stanchina, E.6
-
16
-
-
84876451754
-
Complementary genomic screens identify SERCA as a therapeutic target in NOTCH1 mutated cancer
-
Roti G, Carlton A, Ross KN, Markstein M, Pajcini K, Su AH, et al. Complementary genomic screens identify SERCA as a therapeutic target in NOTCH1 mutated cancer. Cancer Cell 2013; 23: 390-405.
-
(2013)
Cancer Cell
, vol.23
, pp. 390-405
-
-
Roti, G.1
Carlton, A.2
Ross, K.N.3
Markstein, M.4
Pajcini, K.5
Su, A.H.6
-
17
-
-
84964696506
-
Therapeutic targeting of HES1 transcriptional programs in T-ALL
-
Schnell SA, Ambesi-Impiombato A, Sanchez-Martin M, Belver L, Xu L, Qin Y, et al. Therapeutic targeting of HES1 transcriptional programs in T-ALL. Blood 2015; 125: 2806-2814.
-
(2015)
Blood
, vol.125
, pp. 2806-2814
-
-
Schnell, S.A.1
Ambesi-Impiombato, A.2
Sanchez-Martin, M.3
Belver, L.4
Xu, L.5
Qin, Y.6
-
18
-
-
84892622973
-
NOTCH1-RBPJ complexes drive target gene expression through dynamic interactions with superenhancers
-
Wang H, Zang C, Taing L, Arnett KL, Wong YJ, Pear WS, et al. NOTCH1-RBPJ complexes drive target gene expression through dynamic interactions with superenhancers. Proc Natl Acad Sci USA 2014; 111: 705-710.
-
(2014)
Proc Natl Acad Sci USA
, vol.111
, pp. 705-710
-
-
Wang, H.1
Zang, C.2
Taing, L.3
Arnett, K.L.4
Wong, Y.J.5
Pear, W.S.6
-
19
-
-
80052569569
-
Genome-wide analysis reveals conserved and divergent features of Notch1/RBPJ binding in human and murine T-lymphoblastic leukemia cells
-
Wang H, Zou J, Zhao B, Johannsen E, Ashworth T, Wong H, et al. Genome-wide analysis reveals conserved and divergent features of Notch1/RBPJ binding in human and murine T-lymphoblastic leukemia cells. Proc Natl Acad Sci USA 2011; 108: 14908-14913.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 14908-14913
-
-
Wang, H.1
Zou, J.2
Zhao, B.3
Johannsen, E.4
Ashworth, T.5
Wong, H.6
-
20
-
-
67349241955
-
DEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survival
-
Peterson TR, Laplante M, Thoreen CC, Sancak Y, Kang SA, Kuehl WM, et al. DEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survival. Cell 2009; 137: 873-886.
-
(2009)
Cell
, vol.137
, pp. 873-886
-
-
Peterson, T.R.1
Laplante, M.2
Thoreen, C.C.3
Sancak, Y.4
Kang, S.A.5
Kuehl, W.M.6
-
21
-
-
84886531697
-
DEPTOR regulates vascular endothelial cell activation and proinflammatory and angiogenic responses
-
Bruneau S, Nakayama H, Woda CB, Flynn EA, Briscoe DM. DEPTOR regulates vascular endothelial cell activation and proinflammatory and angiogenic responses. Blood 2013; 122: 1833-1842.
-
(2013)
Blood
, vol.122
, pp. 1833-1842
-
-
Bruneau, S.1
Nakayama, H.2
Woda, C.B.3
Flynn, E.A.4
Briscoe, D.M.5
-
22
-
-
84864692282
-
DEPTOR cell-Autonomously promotes adipogenesis, and its expression is associated with obesity
-
Laplante M, Horvat S, Festuccia WT, Birsoy K, Prevorsek Z, Efeyan A, et al. DEPTOR cell-Autonomously promotes adipogenesis, and its expression is associated with obesity. Cell Metab 2012; 16: 202-212.
-
(2012)
Cell Metab
, vol.16
, pp. 202-212
-
-
Laplante, M.1
Horvat, S.2
Festuccia, W.T.3
Birsoy, K.4
Prevorsek, Z.5
Efeyan, A.6
-
23
-
-
84877587720
-
Baf60c drives glycolytic metabolism in the muscle and improves systemic glucose homeostasis through Deptor-mediated Akt activation
-
Meng ZX, Li S, Wang L, Ko HJ, Lee Y, Jung DY, et al. Baf60c drives glycolytic metabolism in the muscle and improves systemic glucose homeostasis through Deptor-mediated Akt activation. Nat Med 2013; 19: 640-645.
-
(2013)
Nat Med
, vol.19
, pp. 640-645
-
-
Meng, Z.X.1
Li, S.2
Wang, L.3
Ko, H.J.4
Lee, Y.5
Jung, D.Y.6
-
24
-
-
84876111472
-
Knockdown of DEPTOR induces apoptosis, increases chemosensitivity to doxorubicin and suppresses autophagy in RPMI-8226 human multiple myeloma cells in vitro
-
Zhang H, Chen J, Zeng Z, Que W, Zhou L. Knockdown of DEPTOR induces apoptosis, increases chemosensitivity to doxorubicin and suppresses autophagy in RPMI-8226 human multiple myeloma cells in vitro. Int J Mol Med 2013; 31: 1127-1134.
-
(2013)
Int J Mol Med
, vol.31
, pp. 1127-1134
-
-
Zhang, H.1
Chen, J.2
Zeng, Z.3
Que, W.4
Zhou, L.5
-
25
-
-
84887380745
-
Knockdown of DEPTOR inhibits cell proliferation and increases chemosensitivity to melphalan in human multiple myeloma RPMI-8226 cells via inhibiting PI3K/AKT activity
-
Zhang HR, Chen JM, Zeng ZY, Que WZ. Knockdown of DEPTOR inhibits cell proliferation and increases chemosensitivity to melphalan in human multiple myeloma RPMI-8226 cells via inhibiting PI3K/AKT activity. J Int Med Res 2013; 41: 584-595.
-
(2013)
J Int Med Res
, vol.41
, pp. 584-595
-
-
Zhang, H.R.1
Chen, J.M.2
Zeng, Z.Y.3
Que, W.Z.4
-
26
-
-
77449090901
-
Dynamic balancing: DEPTOR tips the scales
-
Proud CG. Dynamic balancing: DEPTOR tips the scales. J Mol Cell Biol 2009; 1: 61-63.
-
(2009)
J Mol Cell Biol
, vol.1
, pp. 61-63
-
-
Proud, C.G.1
-
27
-
-
84861697039
-
An evolving role for DEPTOR in tumor development and progression
-
Wang Z, Zhong J, Inuzuka H, Gao D, Shaik S, Sarkar FH, et al. An evolving role for DEPTOR in tumor development and progression. Neoplasia 2012; 14: 368-375.
-
(2012)
Neoplasia
, vol.14
, pp. 368-375
-
-
Wang, Z.1
Zhong, J.2
Inuzuka, H.3
Gao, D.4
Shaik, S.5
Sarkar, F.H.6
-
28
-
-
43549123531
-
The role of the PTEN/AKT Pathway in NOTCH1-induced leukemia
-
Palomero T, Dominguez M, Ferrando AA. The role of the PTEN/AKT Pathway in NOTCH1-induced leukemia. Cell Cycle 2008; 7: 965-970.
-
(2008)
Cell Cycle
, vol.7
, pp. 965-970
-
-
Palomero, T.1
Dominguez, M.2
Ferrando, A.A.3
-
29
-
-
34948908663
-
Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia
-
Palomero T, Sulis ML, Cortina M, Real PJ, Barnes K, Ciofani M, et al. Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia. Nat Med 2007; 13: 1203-1210.
-
(2007)
Nat Med
, vol.13
, pp. 1203-1210
-
-
Palomero, T.1
Sulis, M.L.2
Cortina, M.3
Real, P.J.4
Barnes, K.5
Ciofani, M.6
-
30
-
-
53049085101
-
Oncogenic NOTCH1 control of MYC and PI3K: Challenges and opportunities for anti-NOTCH1 therapy in T-cell acute lymphoblastic leukemias and lymphomas
-
Palomero T, Ferrando A. Oncogenic NOTCH1 control of MYC and PI3K: challenges and opportunities for anti-NOTCH1 therapy in T-cell acute lymphoblastic leukemias and lymphomas. Clin Cancer Res 2008; 14: 5314-5317.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 5314-5317
-
-
Palomero, T.1
Ferrando, A.2
-
31
-
-
84891913160
-
Direct reversal of glucocorticoid resistance by AKT inhibition in acute lymphoblastic leukemia
-
Piovan E, Yu J, Tosello V, Herranz D, Ambesi-Impiombato A, Da Silva AC, et al. Direct reversal of glucocorticoid resistance by AKT inhibition in acute lymphoblastic leukemia. Cancer Cell 2013; 24: 766-776.
-
(2013)
Cancer Cell
, vol.24
, pp. 766-776
-
-
Piovan, E.1
Yu, J.2
Tosello, V.3
Herranz, D.4
Ambesi-Impiombato, A.5
Da Silva, A.C.6
-
32
-
-
0029942842
-
Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles
-
Pear WS, Aster JC, Scott ML, Hasserjian RP, Soffer B, Sklar J, et al. Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles. J Exp Med 1996; 183: 2283-2291.
-
(1996)
J Exp Med
, vol.183
, pp. 2283-2291
-
-
Pear, W.S.1
Aster, J.C.2
Scott, M.L.3
Hasserjian, R.P.4
Soffer, B.5
Sklar, J.6
-
33
-
-
77955134007
-
Clinical utility of microarray-based gene expression profiling in the diagnosis and subclassification of leukemia: Report from the International Microarray Innovations in Leukemia Study Group
-
Haferlach T, Kohlmann A, Wieczorek L, Basso G, Kronnie GT, Bene MC, et al. Clinical utility of microarray-based gene expression profiling in the diagnosis and subclassification of leukemia: report from the International Microarray Innovations in Leukemia Study Group. J Clin Oncol 2010; 28: 2529-2537.
-
(2010)
J Clin Oncol
, vol.28
, pp. 2529-2537
-
-
Haferlach, T.1
Kohlmann, A.2
Wieczorek, L.3
Basso, G.4
Kronnie, G.T.5
Bene, M.C.6
-
34
-
-
77954989425
-
HIV-1 Rev-binding protein accelerates cellular uptake of iron to drive Notch-induced T cell leukemogenesis in mice
-
Khwaja SS, Liu H, Tong C, Jin F, Pear WS, van Deursen J, et al. HIV-1 Rev-binding protein accelerates cellular uptake of iron to drive Notch-induced T cell leukemogenesis in mice. J Clin Invest 2010; 120: 2537-2548.
-
(2010)
J Clin Invest
, vol.120
, pp. 2537-2548
-
-
Khwaja, S.S.1
Liu, H.2
Tong, C.3
Jin, F.4
Pear, W.S.5
Van Deursen, J.6
-
35
-
-
84921628643
-
A NOTCH1-driven MYC enhancer promotes T cell development, transformation and acute lymphoblastic leukemia
-
Herranz D, Ambesi-Impiombato A, Palomero T, Schnell SA, Belver L, Wendorff AA, et al. A NOTCH1-driven MYC enhancer promotes T cell development, transformation and acute lymphoblastic leukemia. Nat Med 2014; 20: 1130-1137.
-
(2014)
Nat Med
, vol.20
, pp. 1130-1137
-
-
Herranz, D.1
Ambesi-Impiombato, A.2
Palomero, T.3
Schnell, S.A.4
Belver, L.5
Wendorff, A.A.6
-
36
-
-
84927169830
-
Novel function of PITH domaincontaining 1 as an activator of internal ribosomal entry site to enhance RUNX1 expression and promote megakaryocyte differentiation
-
Lu B, Sun X, Chen Y, Jin Q, Liang Q, Liu S, et al. Novel function of PITH domaincontaining 1 as an activator of internal ribosomal entry site to enhance RUNX1 expression and promote megakaryocyte differentiation. Cell Mol Life Sci 2015; 72: 821-832.
-
(2015)
Cell Mol Life Sci
, vol.72
, pp. 821-832
-
-
Lu, B.1
Sun, X.2
Chen, Y.3
Jin, Q.4
Liang, Q.5
Liu, S.6
-
37
-
-
84929165873
-
ANGPTL7 regulates the expansion and repopulation of human hematopoietic stem and progenitor cells
-
Xiao Y, Jiang Z, Li Y, Ye W, Jia B, Zhang M, et al. ANGPTL7 regulates the expansion and repopulation of human hematopoietic stem and progenitor cells. Haematologica 2015; 100: 585-594.
-
(2015)
Haematologica
, vol.100
, pp. 585-594
-
-
Xiao, Y.1
Jiang, Z.2
Li, Y.3
Ye, W.4
Jia, B.5
Zhang, M.6
-
38
-
-
84934906688
-
Quantitative evaluation of the immunodeficiency of a mouse strain by tumor engraftments
-
Ye W, Jiang Z, Li GX, Xiao Y, Lin S, Lai Y, et al. Quantitative evaluation of the immunodeficiency of a mouse strain by tumor engraftments. J Hematol Oncol 2015; 8: 59.
-
(2015)
J Hematol Oncol
, vol.8
, pp. 59
-
-
Ye, W.1
Jiang, Z.2
Li, G.X.3
Xiao, Y.4
Lin, S.5
Lai, Y.6
-
39
-
-
81855228182
-
MTOR generates an auto-Amplification loop by triggering the betaTrCP-And CK1alphadependent degradation of DEPTOR
-
Duan S, Skaar JR, Kuchay S, Toschi A, Kanarek N, Ben-Neriah Y, et al. mTOR generates an auto-Amplification loop by triggering the betaTrCP-And CK1alphadependent degradation of DEPTOR. Mol Cell 2011; 44: 317-324.
-
(2011)
Mol Cell
, vol.44
, pp. 317-324
-
-
Duan, S.1
Skaar, J.R.2
Kuchay, S.3
Toschi, A.4
Kanarek, N.5
Ben-Neriah, Y.6
-
40
-
-
81855181738
-
MTOR drives its own activation via SCF(betaTrCP)-dependent degradation of the mTOR inhibitor DEPTOR
-
Gao D, Inuzuka H, Tan MK, Fukushima H, Locasale JW, Liu P, et al. mTOR drives its own activation via SCF(betaTrCP)-dependent degradation of the mTOR inhibitor DEPTOR. Mol Cell 2011; 44: 290-303.
-
(2011)
Mol Cell
, vol.44
, pp. 290-303
-
-
Gao, D.1
Inuzuka, H.2
Tan, M.K.3
Fukushima, H.4
Locasale, J.W.5
Liu, P.6
-
41
-
-
81855167585
-
DEPTOR, an mTOR inhibitor, is a physiological substrate of SCF(betaTrCP) E3 ubiquitin ligase and regulates survival and autophagy
-
Zhao Y, Xiong X, Sun Y. DEPTOR, an mTOR inhibitor, is a physiological substrate of SCF(betaTrCP) E3 ubiquitin ligase and regulates survival and autophagy. Mol Cell 2011; 44: 304-316.
-
(2011)
Mol Cell
, vol.44
, pp. 304-316
-
-
Zhao, Y.1
Xiong, X.2
Sun, Y.3
-
42
-
-
57549102468
-
Identification of primary MAFB target genes in multiple myeloma
-
van Stralen E, van de Wetering M, Agnelli L, Neri A, Clevers HC, Bast BJ. Identification of primary MAFB target genes in multiple myeloma. Exp Hematol 2009; 37: 78-86.
-
(2009)
Exp Hematol
, vol.37
, pp. 78-86
-
-
Van Stralen, E.1
Van De Wetering, M.2
Agnelli, L.3
Neri, A.4
Clevers, H.C.5
Bast, B.J.6
-
43
-
-
84904888382
-
PTEN microdeletions in T-cell acute lymphoblastic leukemia are caused by illegitimate RAG-mediated recombination events
-
Mendes RD, Sarmento LM, Cante-Barrett K, Zuurbier L, Buijs-Gladdines JG, Povoa V, et al. PTEN microdeletions in T-cell acute lymphoblastic leukemia are caused by illegitimate RAG-mediated recombination events. Blood 2014; 124: 567-578.
-
(2014)
Blood
, vol.124
, pp. 567-578
-
-
Mendes, R.D.1
Sarmento, L.M.2
Cante-Barrett, K.3
Zuurbier, L.4
Buijs-Gladdines, J.G.5
Povoa, V.6
-
44
-
-
84916638478
-
ATF4 and N-Myc coordinate glutamine metabolism in MYCN-Amplified neuroblastoma cells through ASCT2 activation
-
Ren P, Yue M, Xiao D, Xiu R, Gan L, Liu H, et al. ATF4 and N-Myc coordinate glutamine metabolism in MYCN-Amplified neuroblastoma cells through ASCT2 activation. J Pathol 2015; 235: 90-100.
-
(2015)
J Pathol
, vol.235
, pp. 90-100
-
-
Ren, P.1
Yue, M.2
Xiao, D.3
Xiu, R.4
Gan, L.5
Liu, H.6
-
45
-
-
33751111683
-
Hsp90 inhibition results in autophagy-mediated proteasome-independent degradation of IkappaB kinase (IKK)
-
Qing G, Yan P, Xiao G. Hsp90 inhibition results in autophagy-mediated proteasome-independent degradation of IkappaB kinase (IKK). Cell Res 2006; 16: 895-901.
-
(2006)
Cell Res
, vol.16
, pp. 895-901
-
-
Qing, G.1
Yan, P.2
Xiao, G.3
-
46
-
-
84921473903
-
The NOTCH ligand JAGGED2 promotes pancreatic cancer metastasis independent of NOTCH signaling activation
-
Hu Y, Su H, Li X, Guo G, Cheng L, Qin R, et al. The NOTCH ligand JAGGED2 promotes pancreatic cancer metastasis independent of NOTCH signaling activation. Mol Cancer Ther 2015; 14: 289-297.
-
(2015)
Mol Cancer Ther
, vol.14
, pp. 289-297
-
-
Hu, Y.1
Su, H.2
Li, X.3
Guo, G.4
Cheng, L.5
Qin, R.6
|