ANGPTL7 regulates the expansion and repopulation of human hematopoietic stem and progenitor cells

Haematologica

Volumn 100, Issue 5, 2015, Pages 585-594

  Xiao, Yiren ^a   Jiang, Zhiwu ^a   Li, Yin ^b   Ye, Wei ^a   Jia, Bei ^c   Zhang, Minjie ^d   Xu, Yan ^e,f   Wu, Donghai ^a   Lai, Liangxue ^a   Chen, Yaoyu ^g   Chang, Yingjun ^h   Huang, Xiaojun ^h   Liu, Hudan ⁱ   Qing, Guoliang ⁱ   Liu, Pentao ^j   Li, Yangqiu ^e,f   Xu, Bing ^b   Zhong, Mei ^c   Yao, Yao ^a   Pei, Duanqing ^a   Li, Peng ^a   more..

^a GUANGZHOU INSTITUTES OF BIOMEDICINE AND HEALTH   (China)

^b SOUTHERN MEDICAL UNIVERSITY   (China)

^c FIRST MILITARY MEDICAL UNIVERSITY   (China)

^d SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGY   (China)

^e MEDICAL COLLEGE OF JINAN UNIVERSITY   (China)

^f JINAN UNIVERSITY   (China)

^g NANJING MEDICAL UNIVERSITY   (China)

^h PEKING UNIVERSITY PEOPLE S HOSPITAL   (China)

ⁱ HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^j WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOPOIETIN; BETA CATENIN; CHEMOKINE RECEPTOR CXCR4; HOMEODOMAIN PROTEIN; POLYHISTIDINE TAG; WNT PROTEIN; ANGPTL7 PROTEIN, HUMAN; ANGPTL7 PROTEIN, MOUSE; HYBRID PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL HOMING; CONTROLLED STUDY; FETUS; FLOW CYTOMETRY; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PROTEIN PURIFICATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA SEQUENCE; STEM CELL EXPANSION; ANIMAL; CELL COMMUNICATION; CLUSTER ANALYSIS; COCULTURE; CYTOLOGY; DRUG EFFECTS; FETUS BLOOD; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENETICS; KNOCKOUT MOUSE; METABOLISM; STROMA CELL; WNT SIGNALING PATHWAY;

ANGIOPOIETINS; ANIMALS; CELL COMMUNICATION; CLUSTER ANALYSIS; COCULTURE TECHNIQUES; FETAL BLOOD; GENE EXPRESSION; GENE EXPRESSION PROFILING; HEMATOPOIETIC STEM CELLS; HUMANS; MICE; MICE, KNOCKOUT; RECOMBINANT FUSION PROTEINS; STROMAL CELLS; WNT SIGNALING PATHWAY;

EID: 84929165873     PISSN: 03906078     EISSN: 15928721     Source Type: Journal    
DOI: 10.3324/haematol.2014.118612     Document Type: Article

References (59)

1. Zon LI. Intrinsic and extrinsic control of haematopoietic stem-cell self-renewal. Nature. 2008;453(7193):306-313.
2. Kiel MJ, Morrison SJ. Uncertainty in the niches that maintain haematopoietic stem cells. Nat Rev Immunol. 2008;8(4):290-301.
3. Yilmaz OH, Valdez R, Theisen BK, et al. Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells. Nature. 2006;441(7092):475-482.
4. Antonchuk J, Sauvageau G, Humphries RK. HOXB4-induced expansion of adult hematopoietic stem cells ex vivo. Cell. 2002;109(1):39-45.
5. Will B, Vogler TO, Bartholdy B, et al. Satb1 regulates the self-renewal of hematopoietic stem cells by promoting quiescence and repressing differentiation commitment. Nat Immunol. 2013;14(5):437-445.
6. Kalaitzidis D, Sykes SM, Wang Z, et al. mTOR complex 1 plays critical roles in hematopoiesis and Pten-loss-evoked leukemogenesis. Cell Stem Cell. 2012;11(3):429-439.
7. Chute JP, Saini AA, Chute DJ, et al. Ex vivo culture with human brain endothelial cells increases the SCID-repopulating capacity of adult human bone marrow. Blood. 2002; 100(13):4433-4439.
8. Oostendorp RA, Harvey KN, Kusadasi N, et al. Stromal cell lines from mouse aortagonads-mesonephros subregions are potent supporters of hematopoietic stem cell activity. Blood. 2002;99(4):1183-1189.
9. Chou S, Lodish HF. Fetal liver hepatic progenitors are supportive stromal cells for hematopoietic stem cells. Proc Natl Acad Sci USA. 2010;107(17):7799-7804.
10. Chu SH, Heiser D, Li L, et al. FLT3-ITD knockin impairs hematopoietic stem cell quiescence/homeostasis, leading to myeloproliferative neoplasm. Cell Stem Cell. 2012;11(3) 346-358.
11. Yamazaki S, Ema H, Karlsson G, et al. Nonmyelinating Schwann cells maintain hematopoietic stem cell hibernation in the bone marrow niche. Cell. 2011; 147(5):1146-1158.
12. Greenbaum A, Hsu YM, Day RB, et al. CXCL12 in early mesenchymal progenitors is required for haematopoietic stem-cell maintenance. Nature. 2013;495(7440):227-230.
13. Himburg HA, Muramoto GG, Daher P, et al. Pleiotrophin regulates the expansion and regeneration of hematopoietic stem cells. Nat Med. 2010;16(4):475-482.
14. Zhang CC, Kaba M, Ge G, et al. Angiopoietin-like proteins stimulate ex vivo expansion of hematopoietic stem cells. Nat Med. 2006;12(2):240-245.
15. Zheng J, Umikawa M, Cui C, et al. Inhibitory receptors bind ANGPTLs and support blood stem cells and leukaemia development. Nature. 2012;485(7400):656-660.
16. Doan PL, Himburg HA, Helms K, et al. Epidermal growth factor regulates hematopoietic regeneration after radiation injury. Nat Med. 2013;19(3):295-304.
17. Reya T, Duncan AW, Ailles L, et al. A role for Wnt signalling in self-renewal of haematopoietic stem cells. Nature. 2003; 423(6938):409-414.
18. Baba Y, Yokota T, Spits H, Garrett KP, Hayashi S, Kincade PW. Constitutively active beta-catenin promotes expansion of multipotent hematopoietic progenitors in culture. J Immunol. 2006;177(4):2294-2303.
19. Huang J, Nguyen-McCarty M, Hexner EO, Danet-Desnoyers G, Klein PS. Maintenance of hematopoietic stem cells through regulation of Wnt and mTOR pathways. Nat Med. 2012;18(12):1778-1785.
20. Hato T, Tabata M, Oike Y. The role of angiopoietin-like proteins in angiogenesis and metabolism. Trends Cardiovasc Med. 2008;18(1):6-14.
21. Comes N, Buie LK, Borras T. Evidence for a role of angiopoietin-like 7 (ANGPTL7) in extracellular matrix formation of the human trabecular meshwork: implications for glaucoma. Genes Cells. 2011;16(2):243-259.
22. Oike Y, Tabata M. Angiopoietin-like proteins--potential therapeutic targets for metabolic syndrome and cardiovascular disease. Circ J. 2009;73(12):2192-2197.
23. Akhter S, Rahman MM, Lee HS, Kim HJ, Hong ST. Dynamic roles of angiopoietin-like proteins 1, 2, 3, 4, 6 and 7 in the survival and enhancement of ex vivo expansion of bonemarrow hematopoietic stem cells. Protein Cell. 2013;4(3):220-230.
24. Zhang CC, Kaba M, Iizuka S, Huynh H, Lodish HF. Angiopoietin-like 5 and IGFBP2 stimulate ex vivo expansion of human cord blood hematopoietic stem cells as assayed by NOD/SCID transplantation. Blood. 2008;111(7):3415-3423.
25. Wang T, Cui Y, Jin J, et al. Translating mRNAs strongly correlate to proteins in a multivariate manner and their translation ratios are phenotype specific. Nucleic Acids Res. 2013;41(9):4743-4754.
26. Zhong J, Cui Y, Guo J, et al. Resolving chromosome-centric human proteome with translating mRNA analysis: a strategic demonstration. J Proteome Res. 2014; 13(1):50-59.
27. Yuan Y, Yu B, Song S, et al. [Targeted exogenous EGFP gene editing in caprine fetus fibroblasts by zinc-finger nucleases]. Sheng Wu Gong Cheng Xue Bao. 2013; 29(11):1573-1580.
28. Rehn M, Olsson A, Reckzeh K, et al. Hypoxic induction of vascular endothelial growth factor regulates murine hematopoietic stem cell function in the low-oxygenic niche. Blood. 2011;118(6):1534-1543.
29. Huang S, Okamoto K, Yu C, Sinicrope FA. p62/sequestosome-1 up-regulation promotes ABT-263-induced caspase-8 aggregation/activation on the autophagosome. J Biol Chem. 2013;288(47):33654-333666.
30. Jia W, Gao XJ, Zhang ZD, Yang ZX, Zhang G. S100A4 silencing suppresses proliferation, angiogenesis and invasion of thyroid cancer cells through downregulation of MMP-9 and VEGF. Eur Rev Med Pharmacol Sci. 2013;17(11):1495-1508.
31. Zhu HL, Wei X, Qu SL, et al. Ischemic postconditioning protects cardiomyocytes against ischemia/reperfusion injury by inducing MIP2. Exp Mol Med. 2011; 43(8):437-445.
32. Kolar P, Gaber T, Perka C, Duda GN, Buttgereit F. Human early fracture hematoma is characterized by inflammation and hypoxia. Clin Orthop Relat Res. 2011;469(11):3118-3126.
33. Fleming HE, Janzen V, Lo Celso C, et al. Wnt signaling in the niche enforces hematopoietic stem cell quiescence and is necessary to preserve self-renewal in vivo. Cell Stem Cell. 2008;2(3):274-283.
34. Trowbridge JJ, Moon RT, Bhatia M. Hematopoietic stem cell biology: too much of a Wnt thing. Nat Immunol. 2006;7(10): 1021-1023.
35. Eaves CJ. Manipulating hematopoietic stem cell amplification with Wnt. Nat Immunol. 2003;4(6):511-512.
36. Li VS, Ng SS, Boersema PJ, et al. Wnt signaling through inhibition of beta-catenin degradation in an intact Axin1 complex. Cell. 2012;149(6):1245-1256.
37. Yu HM, Jerchow B, Sheu TJ, et al. The role of Axin2 in calvarial morphogenesis and craniosynostosis. Development. 2005; 132(8):1995-2005.
38. Merrill BJ, Pasolli HA, Polak L, et al. Tcf3: a transcriptional regulator of axis induction in the early embryo. Development. 2004; 131(2):263-274.
39. Galceran J, Farinas I, Depew MJ, Clevers H, Grosschedl R. Wnt3a-/--like phenotype and limb deficiency in Lef1(-/-)Tcf1(-/-) mice. Genes Dev. 1999;13(6):709-717.
40. Shtutman M, Zhurinsky J, Simcha I, et al. The cyclin D1 gene is a target of the betacatenin/LEF-1 pathway. Proc Natl Acad Sci USA. 1999;96(10):5522-5527.
41. Verbeek S, Izon D, Hofhuis F, et al. An HMG-box-containing T-cell factor required for thymocyte differentiation. Nature. 1995;374(6517):70-74.
42. He TC, Sparks AB, Rago C, et al. Identification of c-MYC as a target of the APC pathway. Science. 1998;281(5382): 1509-1512.
43. Smith-Berdan S, Nguyen A, Hassanein D, et al. Robo4 cooperates with CXCR4 to specify hematopoietic stem cell localization to bone marrow niches. Cell Stem Cell. 2011;8(1):72-83.
44. Jackson M, Axton RA, Taylor AH, et al. HOXB4 can enhance the differentiation of embryonic stem cells by modulating the hematopoietic niche. Stem Cells. 2012; 30(2):150-160.
45. Behrens J, Jerchow BA, Wurtele M, et al. Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta. Science. 1998;280(5363):596-599.
46. Blauwkamp TA, Nigam S, Ardehali R, Weissman IL, Nusse R. Endogenous Wnt signalling in human embryonic stem cells generates an equilibrium of distinct lineagespecified progenitors. Nat Commun. 2012; 3:1070.
47. Hawcroft G, D’Amico M, Albanese C, Markham AF, Pestell RG, Hull MA. Indomethacin induces differential expression of beta-catenin, gamma-catenin and Tcell factor target genes in human colorectal cancer cells. Carcinogenesis. 2002; 23(1):107-114.
48. Kapitanovic S, Cacev T, Antica M, et al. Effect of indomethacin on E-cadherin and beta-catenin expression in HT-29 colon cancer cells. Exp Mol Pathol. 2006;80(1): 91-96.
49. Mao B, Wu W, Davidson G, et al. Kremen proteins are Dickkopf receptors that regulate Wnt/beta-catenin signalling. Nature. 2002;417(6889):664-667.
50. Arai F, Hirao A, Ohmura M, et al. Tie2/angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche. Cell. 2004;118(2):149-161.
51. Zheng J, Umikawa M, Zhang S, et al. Ex vivo expanded hematopoietic stem cells overcome the MHC barrier in allogeneic transplantation. Cell Stem Cell. 2011; 9(2):119-130.
52. Mohle R, Bautz F, Rafii S, Moore MA, Brugger W, Kanz L. The chemokine receptor CXCR-4 is expressed on CD34+ hematopoietic progenitors and leukemic cells and mediates transendothelial migration induced by stromal cell-derived factor-1. Blood. 1998;91(12):4523-4530.
53. Gomei Y, Nakamura Y, Yoshihara H, et al. Functional differences between two Tie2 ligands, angiopoietin-1 and-2, in regulation of adult bone marrow hematopoietic stem cells. Exp Hematol. 2010;38(2):82-89.
54. Willert K, Brown JD, Danenberg E, et al. Wnt proteins are lipid-modified and can act as stem cell growth factors. Nature. 2003; 423(6938):448-452.
55. Tu X, Joeng KS, Nakayama KI, et al. Noncanonical Wnt signaling through G protein-linked PKCdelta activation promotes bone formation. Dev Cell. 2007; 12(1):113-127.
56. Sugimura R, He XC, Venkatraman A, et al. Noncanonical Wnt signaling maintains hematopoietic stem cells in the niche. Cell. 2012;150(2):351-365.
57. Huls G, van Es J, Clevers H, de Haan G, van Os R. Loss of Tcf7 diminishes hematopoietic stem/progenitor cell function. Leukemia. 2013;27(7):1613-1614.
58. Rossi L, Lin KK, Boles NC, et al. Less is more: unveiling the functional core of hematopoietic stem cells through knockout mice. Cell Stem Cell. 2012;11(3):302-317.
59. Staal FJ, van Dongen JJ, Langerak AW. Novel insights into the development of T-cell acute lymphoblastic leukemia. Curr Hematol Malig Rep. 2007;2(3):176-182.